Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https://t.co/NC0ESS19iy #CCR25 | @CritCareReviews https://t.co/S11ksT9YEm
Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation.
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Apr 2023 – Sep 2025Where it's discussed
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X / Twitter53 posts
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News9 articles
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Blogs3 articles
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Bluesky2 posts
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YouTube2 videos
AI synopsis
What people are saying
The discussions contain various reflections on the PROMIZING trial, where users highlight outcomes like 'no significant difference in the duration of mechanical ventilation' between PAV+ and PSV. Phrases such as 'silly study' indicate skepticism, while others express appreciation for the rigorous design of the trial by mentioning the variety of clinical settings involved. This mix of humor, skepticism, and detailed breakdown of results showcases the participants' varying levels of engagement with the study.
The discussions reflect a mix of opinions, with some expressing skepticism towards the study's significance while others support its findings.
There is moderate interest as many users share details from the study and its implications for clinical practice.
Participants engage with the content by referencing methods and discussing their experiences, although few show deep personal reflections.
Impact perception is low as the consensus suggests that the study did not demonstrate clear advantages for one method over the other.
Abstract in brief
- In critically ill patients, a study compared two ventilation methods: proportional-assist ventilation with load-adjustable gain factors (PAV+) and pressure-support ventilation (PSV) to see which one leads to a quicker recovery from mechanical ventilation.
- The trial involved 573 patients across 23 centers in seven countries, finding a median liberation time of 7.3 days for PAV+ compared to 6.8 days for PSV, indicating no significant difference.
- Both groups showed similar rates of ventilator-free days, reintubation, and death by day 90, suggesting that neither method offered a clear advantage in long-term outcomes.
Top posts
Most liked on X and BlueskyOriginal Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https://t.co/NC0ESS19iy #Pulmonology #CriticalCare https://t.co/gzBMDMjcok
PAV+がPSVと比較して呼吸器離脱期間を短縮できるかという多施設RCT。Primary Outcomeは7日以上再挿管なし。結果有意差はなし。90日死亡率/再挿管/気切の割合も同様。鎮静薬使用量や呼吸筋活動指標ではPAV+群が優勢かも。PAV+使い慣れる必要があるしやりたいかと言われると... https://t.co/YqItxEwbDH
The sixth trial result for #CCR25 in Titanic Belfast in June is PROMIZING Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation Register at criticalcarereviews.com/meetings/ccr25
まさかのPROMIZING studyはNEJMからのpublish PAV+ vs PSVの23施設, n=733 RCT 今後はpost hoc analysisで様々な生理学的評価が明らかになることでしょう https://t.co/wNjYHORCwu
②PROMIZING trial|NEJM 人工呼吸からの離脱段階で、PAV+ vs PSV(n=573) 離脱までの時間に差なし(7.3日 vs 6.8日)
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Key Studies in Pulmonary and Critical Care Medicine
In this week's episode, we break down five pivotal studies every pulmonologist, intensivist, and respiratory therapist should know. From ventilator liberation strategies to practical procedural tips, we cover the latest…
Comparison of PAV+ and PSV in Mechanical Ventilation Recovery
In critically ill patients, this study compared proportional-assist ventilation (PAV+) and pressure-support ventilation (PSV) to determine which method leads to quicker mechanical ventilation recovery. Findings revealed…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
In the PROMIZING trial, proportional-assist ventilation with load-adjustable gain factors did not differ significantly from pressure-support ventilation with respect to the time to liberation from mechanical ventilation. Full trial results and Research Summary: nej.md/4kC2a67 #MedSky #PulmSky
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https://t.co/NC0ESS19iy #Pulmonology #CriticalCare https://t.co/gzBMDMjcok
https://t.co/EYmi8lsnMg 重症患者においてPAV+がPSVに比べて人工呼吸離脱までの時間を短縮するかを調べたRCT 結果は離脱までの時間は両群間で差はなかった(7.3vs6.8d)、また人工呼吸フリー日数、再挿管、気管切開率、90日死亡率、重篤な合併症も差がなかった #当麻_呼吸
https://t.co/ofBGv34MFx Silly study, we already have SIMV - the ULTIMATE in vent weaning
Episode 69! We talk about the articles from the #CCR25 conference with RESCUE-3 published in @ATSBlueEditor by Dres et al and PROMIZING by Bosma et al in @NEJM RESCUE-3: https://t.co/Xfldl0gEuz PROMIZING: https://t.co/4Tw8tEMdVx Listen: https://t.co/qPyhTM3p2C
PAV+はPSVと比較し人工呼吸器離脱までの期間を短縮せず。 PSVの離脱プロトコルと比較したところで、やってることは本質的に同じである気もするが...。この辺も個別化が必要なのかなと。 https://t.co/kLWp33SKbD
② PROMIZING trial|NEJM PAV+ vs PSV during weaning from mechanical ventilation (n=573) No difference in time to liberation (7.3 vs 6.8 days)
②PROMIZING trial|NEJM 人工呼吸からの離脱段階で、PAV+ vs PSV(n=573) 離脱までの時間に差なし(7.3日 vs 6.8日)
Congratulations to all NYG team members who participated in the PROMIZING international trial that was recently published in the @NEJM. Your commitment underscores NYG’s dedication to impactful, high-quality clinical research on a global scale! https://t.co/82nERvaKt7 #NYGProud https://t.co/kxB3VWlnVt
【PROMIZING試験(NEJM, 2025)】 人工呼吸器からの早期離脱にPAV+とPSVのどちらが有用か? →primary outcome(離脱までの期間)に有意差なし。死亡率や再挿管率も同等。 https://t.co/8pnKCatW6X
Proportional-assist ventilation did not significantly shorten mechanical ventilation duration compared to pressure-support ventilation in critically ill patients. by Bosma KJ, Burns KEA (...) Brochard L et 44 al. in N Engl J Med https://t.co/raazRNFMbO #MedX #MedResearch
New episode of “This Week in Pulmonary and Critical Care” ✅ Switching from Controlled to Assisted Ventilation ✅ PROMIZING: PAV+ vs. PSV ✅ High-Flow O2 for Bronch in COPD ✅ Biopsy of lung Nodules: Inside-Out vs. Outside-In ✅ Pleural Fluid Analysis https://t.co/oqbLQfzDPM
Sticking w/ pressure support. No benefit of PAV+ for duration of mech vent. While, Vent-free days, reintubation, & tracheostomy less w/ PSV (p<0.20, but>0.05) Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation | NEJM https://t.co/Lj1eOK1SgM
PAV+は人工呼吸器離脱(抜管)を早めるか? @NEJM PAV+群 vs PSV群 →7.3日 (95% CI, 6.2-9.7) vs 6.8日 (95% CI, 5.4-8.8) 副次的評価項目も有意差なし https://t.co/EcXjTYwujP
RT @tipssovetorax: De 20 millones de personas en el mundo con ventilación mecánica invasiva VMI al año, 35 % tendrá retiro gradual del resp…
RT @tipssovetorax: De 20 millones de personas en el mundo con ventilación mecánica invasiva VMI al año, 35 % tendrá retiro gradual del resp…
De 20 millones de personas en el mundo con ventilación mecánica invasiva VMI al año, 35 % tendrá retiro gradual del respirador difícil o largo, o fallecerá. VMI prolongada se asocia a mas riesgo de complicacion, muerte y secuelas a largo plazo y mayor costo 10.1056/NEJMoa2505708
@ISICEM Critical Care Input Proportional-Assist Ventilation for Minimizing the Duration of #MechanicalVentilation #ISICEMelearning #MedED @NEJM
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation #science #publication #research #publications https://t.co/fJbQrOHzsC
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation | New England Journal of Medicine Neutral study
RT @NEJM: Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https:/…
Original Article: Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING trial) https://t.co/NC0ESS19iy #CCR25 | @CritCareReviews https://t.co/S11ksT9YEm
RT @Cafe_Dogtor: PAV+がPSVと比較して呼吸器離脱期間を短縮できるかという多施設RCT。Primary Outcomeは7日以上再挿管なし。結果有意差はなし。90日死亡率/再挿管/気切の割合も同様。鎮静薬使用量や呼吸筋活動指標ではPAV+群が優勢かも。PAV…
RT @Cafe_Dogtor: PAV+がPSVと比較して呼吸器離脱期間を短縮できるかという多施設RCT。Primary Outcomeは7日以上再挿管なし。結果有意差はなし。90日死亡率/再挿管/気切の割合も同様。鎮静薬使用量や呼吸筋活動指標ではPAV+群が優勢かも。PAV…
RT @Cafe_Dogtor: PAV+がPSVと比較して呼吸器離脱期間を短縮できるかという多施設RCT。Primary Outcomeは7日以上再挿管なし。結果有意差はなし。90日死亡率/再挿管/気切の割合も同様。鎮静薬使用量や呼吸筋活動指標ではPAV+群が優勢かも。PAV…
RT @Cafe_Dogtor: PAV+がPSVと比較して呼吸器離脱期間を短縮できるかという多施設RCT。Primary Outcomeは7日以上再挿管なし。結果有意差はなし。90日死亡率/再挿管/気切の割合も同様。鎮静薬使用量や呼吸筋活動指標ではPAV+群が優勢かも。PAV…
RT @Cafe_Dogtor: PAV+がPSVと比較して呼吸器離脱期間を短縮できるかという多施設RCT。Primary Outcomeは7日以上再挿管なし。結果有意差はなし。90日死亡率/再挿管/気切の割合も同様。鎮静薬使用量や呼吸筋活動指標ではPAV+群が優勢かも。PAV…
PAV+がPSVと比較して呼吸器離脱期間を短縮できるかという多施設RCT。Primary Outcomeは7日以上再挿管なし。結果有意差はなし。90日死亡率/再挿管/気切の割合も同様。鎮静薬使用量や呼吸筋活動指標ではPAV+群が優勢かも。PAV+使い慣れる必要があるしやりたいかと言われると... https://t.co/YqItxEwbDH
RT @moto_moto_moto: まさかのPROMIZING studyはNEJMからのpublish PAV+ vs PSVの23施設, n=733 RCT 今後はpost hoc analysisで様々な生理学的評価が明らかになることでしょう https://t.…
RT @moto_moto_moto: まさかのPROMIZING studyはNEJMからのpublish PAV+ vs PSVの23施設, n=733 RCT 今後はpost hoc analysisで様々な生理学的評価が明らかになることでしょう https://t.…
RT @moto_moto_moto: まさかのPROMIZING studyはNEJMからのpublish PAV+ vs PSVの23施設, n=733 RCT 今後はpost hoc analysisで様々な生理学的評価が明らかになることでしょう https://t.…
Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation | New England Journal of Medicine https://t.co/TcyuCiYxxf
まさかのPROMIZING studyはNEJMからのpublish PAV+ vs PSVの23施設, n=733 RCT 今後はpost hoc analysisで様々な生理学的評価が明らかになることでしょう https://t.co/wNjYHORCwu
RT @CritCareReviews: The sixth trial result for #CCR25 in @TitanicBelfast in June is PROMIZING from @CCCTG_ Proportional Assist Ventilati…
RT @CritCareReviews: The sixth trial result for #CCR25 in @TitanicBelfast in June is PROMIZING from @CCCTG_ Proportional Assist Ventilati…
RT @CritCareReviews: The sixth trial result for #CCR25 in @TitanicBelfast in June is PROMIZING from @CCCTG_ Proportional Assist Ventilati…
RT @CritCareReviews: The sixth trial result for #CCR25 in @TitanicBelfast in June is PROMIZING from @CCCTG_ Proportional Assist Ventilati…
The sixth trial result for #CCR25 in Titanic Belfast in June is PROMIZING Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation Register at criticalcarereviews.com/meetings/ccr25
The sixth trial result for #CCR25 in @TitanicBelfast in June is PROMIZING from @CCCTG_ Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation #CCR25 - The Best Critical Care Trials in the World Register via the QR code or on the CCR website https://t.co/fgiTrQNFhA
#Study #protocol for a #randomized #controlled #trial of Proportional Assist #Ventilation for Minimizing the Duration of #Mechanical Ventilation: the PROMIZING study https://t.co/ekBeF2URiW https://t.co/Ewf6ICQ9pE