Front Immunol June 2025 PMID 40529366

Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review.

Xianghui Zhao, Peiying Lv, Zixing Cai, Jun Dong, Wenxiang Chen, Liang Sun, Ruiyue Yang

Mentions

6
Peak: 4 in Jun 2025
across 2 sources since Jun 2025

Extended reach

239,757
potential audience

Total likes

8,715

Video views

191,849

Mentions per month

Jun 2025 – Sep 2025

Where it's discussed

  • X / Twitter4 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall tone reflects a strong interest in the potential of CD38 research, with posts emphasizing its role in aging and therapies, exemplified by phrases like 'potential key for therapies' and 'more studies needed,' indicating optimism about future developments and a recognition of the article’s significance in advancing aging research.

AgreementModerate agreement

Most discussions recognize the importance of CD38 in aging and disease, aligning with the article's implications that understanding this enzyme could lead to significant medical advances.

InterestHigh interest

The posts consistently show high curiosity about the research, highlighting keywords like 'crucial role,' 'therapies,' and 'new insights,' indicating strong engagement with the topic.

EngagementModerate engagement

Several posts reference specific aspects such as the bibliometric analysis and the focus on different countries, showing a desire to discuss detailed findings rather than superficial mentions.

ImpactModerate impact

The discussions suggest a belief that further research on CD38 could greatly influence therapeutic strategies and understanding of aging, suggesting perceived and potential high impact.

Abstract in brief

  • The article explains that CD38 is a glycoprotein involved in metabolizing NAD, a crucial coenzyme for energy production, cell death, and DNA repair, and its role is particularly important in aging and related diseases.
  • It reports findings from a bibliometric analysis showing a significant increase in research on CD38, mostly led by the US and China, with key focus areas including blood disorders, NAD metabolism, and potential therapeutic uses of targeting CD38.
  • The study emphasizes that understanding CD38's functions and mechanisms could help develop new strategies for diagnosing and treating age-related diseases, making CD38 a promising focus for future medical research.

Top posts

Most liked on X and Bluesky
Frontiers - Immunology
@FrontImmunol · X

New Research: Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review https://t.co/aD4VQ9V3aB #FrontiersIn #Immunology

Jun 11, 2025 · 2 likes · 33,825 followers View post →
Thrivous
@thrivous · X

CD38 may play a crucial role in aging and diseases. Research is booming, especially in the US and China. Scientists see CD38 as a potential key for therapies. More studies are needed for deeper insights. https://t.co/DALfGNFvKv

Jun 18, 2025 · 1 like · 11,794 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review https://t.co/lN6hkAvgH6

Jun 18, 2025 · 1 like · 2,239 followers View post →
inmunoes
@inmunoes · X

Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review https://t.co/YPrAHoVbel #FrontImmunol

Jun 2, 2025 · 51 followers View post →

All mentions

Thrivous
@thrivous · X

CD38 may play a crucial role in aging and diseases. Research is booming, especially in the US and China. Scientists see CD38 as a potential key for therapies. More studies are needed for deeper insights. https://t.co/DALfGNFvKv

Jun 18, 2025 · 1 like · 11,794 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review https://t.co/lN6hkAvgH6

Jun 18, 2025 · 1 like · 2,239 followers View post →
Frontiers - Immunology
@FrontImmunol · X

New Research: Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review https://t.co/aD4VQ9V3aB #FrontiersIn #Immunology

Jun 11, 2025 · 2 likes · 33,825 followers View post →
inmunoes
@inmunoes · X

Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review https://t.co/YPrAHoVbel #FrontImmunol

Jun 2, 2025 · 51 followers View post →