N Engl J Med July 2025 PMID 40673696

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease.

Louise A Hyslop, Emma L Blakely, Magomet Aushev, Jordan Marley, Yuko Takeda, Angela Pyle, Eilis Moody, Catherine Feeney, Jan Dutton, Carol Shaw, Sarah J Smith, Kate Craig, Charlotte L Alston, Lisa Lister, Karina Endacott

Mentions

520
Peak: 130 in Jul 2025
across 6 sources since Jul 2025

Extended reach

4,803,558
potential audience

Total likes

4,114

Video views

131,760

Mentions per month

Jul 2025 – Sep 2025

Where it's discussed

  • News366 articles
  • X / Twitter121 posts
  • Bluesky16 posts
  • Blogs10 articles
  • Facebook4 posts
  • YouTube3 videos

AI synopsis

What people are saying

Several discussions provide insights into the publication's findings, noting how mitochondrial donation has successfully reduced harmful mtDNA variants, with phrases like 'game changer' and 'brave new world' reflecting the excitement and forward-looking perspective of the community. The overall tone is optimistic, showcasing a blend of scientific enthusiasm and a call for further research, which strongly contributes to the positive sentiment captured.

AgreementModerate agreement

Most discussions reflect a general support for the methods proposed in the publication, acknowledging their potential benefits in reducing mtDNA disease transmission.

InterestHigh interest

There is a noticeable enthusiasm and curiosity regarding mitochondrial donation and its implications for reproductive technology, indicating a high interest level.

EngagementModerate engagement

While many posts summarize the findings, a few demonstrate deeper engagement by discussing the implications for future research and potential ethical considerations.

ImpactHigh impact

The discussions suggest that the publication is perceived to have a significant impact on how mitochondrial diseases are addressed, with many viewing it as a breakthrough.

Abstract in brief

  • Mitochondrial diseases can be passed from mothers to children due to harmful mutations in mitochondrial DNA (mtDNA), but mitochondrial donation and preimplantation genetic testing (PGT) can help reduce this risk.
  • Mitochondrial donation by pronuclear transfer involves transferring the mother's nuclear DNA to a healthy egg to create a child with less risk of mtDNA disease, while PGT specializes in identifying and selectively using embryos with lower risk.
  • The study showed that out of patients who underwent either method, 8 live births resulted from pronuclear transfer and 18 from PGT, indicating both techniques are viable for reducing the transmission of harmful mtDNA variants.

Top posts

Most liked on X and Bluesky
NEJM
@NEJM · X

Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Science behind the Study: Advances in https://t.co/u3MO2sHffT

Jul 18, 2025 · 57 likes · 17 shares · 935,633 followers View post →
NEJM
@NEJM · X

Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Science behind the Study: Advances in https://t.co/T1BMSiil8B

Jul 17, 2025 · 54 likes · 20 shares · 935,633 followers View post →
NEJM
@NEJM · X

New in the July 31, 2025, issue of NEJM: MRD-Guided Therapy in Newly Diagnosed Myeloma (MIDAS phase 3 trial) https://t.co/GXEKDda6he Mitochondrial Donation and PGT in mtDNA Disease https://t.co/RZBIm2yak5 Acute Normovolemic Hemodilution in Cardiac Surgery (ANH phase 3 https://t.co/VWWYwk9uqf

Jul 31, 2025 · 34 likes · 4 shares · 935,633 followers View post →
NEJM
@NEJM · X

Women with homoplasmic variations in mitochondrial DNA are at high risk for having affected biologic children. This study tests a new method to subvert the transmission of mitochondrial disease from mother to offspring. Full study results: https://t.co/RZBIm2yak5 https://t.co/X110GMuYSr

Aug 1, 2025 · 27 likes · 4 shares · 935,633 followers View post →
Catalina Vasilescu, PhD
@cvasilescu.bsky.social · Bluesky

#MitochondrialDisease selection of papers from #week29!

Jul 20, 2025 · 19 likes · 10 shares View post →
Catalina Vasilescu, PhD
@_CVasilescu · X

#MitochondrialDisease selection of papers from #week29!

Jul 20, 2025 · 12 likes · 4 shares · 1,049 followers View post →

All mentions

Lynn Dickerson
@LynnDic76525801 · X

RT @CMichaelGibson: Mitochondrial donation through pronuclear transfer is compatible with human embryo viability and reduces the transmissi…

Sep 10, 2025 · 1 share · 5 followers View post →
水城ゆき
@AiloveTh · X

https://t.co/lXFippReZ1 すごい

Aug 22, 2025 · 879 followers View post →
Peace of Mind
@Peacefu08099959 · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/HICDP0mcu7

Aug 10, 2025 · 310 followers View post →
STITCHES Medicine - the Best of Medical Research
@medicine.stitches.today · Bluesky

Mitochondrial donation and genetic testing significantly reduced the risk of mtDNA disease in children born to affected mothers. by Hyslop LA, Blakely EL (...) Herbert M et 28 al. in N Engl J Med #MedSky

Aug 9, 2025 · 1 like View post →
STITCHES Medicine - the Best of Medical Research
@STITCHESMed · X

Mitochondrial donation and genetic testing significantly reduced the risk of mtDNA disease in children born to affected mothers. by Hyslop LA, Blakely EL (...) Herbert M et 28 al. in N Engl J Med https://t.co/CKG9ZYlfU5 #MedX #MedResearch

Aug 9, 2025 · 83 followers View post →
AGM : Association Guerrier Mitochondrial
@AgmAssociation · X

RT @Emit38935125: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/3DpD0cyLhD

Aug 4, 2025 · 1 share · 44 followers View post →
E-mit
@Emit38935125 · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/3DpD0cyLhD

Aug 4, 2025 · 4 likes · 1 share · 1,371 followers View post →
Jorge Pacheco Jara
@jorge_pacheco · X

RT @NEJM: Women with homoplasmic variations in mitochondrial DNA are at high risk for having affected biologic children. This study tests a…

Aug 1, 2025 · 4 shares · 8,326 followers View post →
旅人 tabito
@tabibito250 · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/RamWHFOGDq

Aug 1, 2025 · 1 like · 1,075 followers View post →
NEJM
@NEJM · X

Women with homoplasmic variations in mitochondrial DNA are at high risk for having affected biologic children. This study tests a new method to subvert the transmission of mitochondrial disease from mother to offspring. Full study results: https://t.co/RZBIm2yak5 https://t.co/X110GMuYSr

Aug 1, 2025 · 27 likes · 4 shares · 935,633 followers View post →
Marko
@Markotelomerase · X

RT @NEJM: New in the July 31, 2025, issue of NEJM: MRD-Guided Therapy in Newly Diagnosed Myeloma (MIDAS phase 3 trial) https://t.co/GXEK…

Jul 31, 2025 · 4 shares · 59 followers View post →
Emmanuel Edwar Siddig
@emmanue34897812 · X

RT @NEJM: New in the July 31, 2025, issue of NEJM: MRD-Guided Therapy in Newly Diagnosed Myeloma (MIDAS phase 3 trial) https://t.co/GXEK…

Jul 31, 2025 · 4 shares · 309 followers View post →
Adam Cifu
@adamcifu · X

Um, wow. A brave new world indeed. Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/Cpl8hcchTI

Jul 31, 2025 · 3 likes · 26,015 followers View post →
Martin Correa
@martinrafco · X

RT @NEJM: New in the July 31, 2025, issue of NEJM: MRD-Guided Therapy in Newly Diagnosed Myeloma (MIDAS phase 3 trial) https://t.co/GXEK…

Jul 31, 2025 · 4 shares · 233 followers View post →
Guillermo
@Guillesuarezc · X

RT @NEJM: New in the July 31, 2025, issue of NEJM: MRD-Guided Therapy in Newly Diagnosed Myeloma (MIDAS phase 3 trial) https://t.co/GXEK…

Jul 31, 2025 · 4 shares · 1,669 followers View post →
NEJM
@NEJM · X

New in the July 31, 2025, issue of NEJM: MRD-Guided Therapy in Newly Diagnosed Myeloma (MIDAS phase 3 trial) https://t.co/GXEKDda6he Mitochondrial Donation and PGT in mtDNA Disease https://t.co/RZBIm2yak5 Acute Normovolemic Hemodilution in Cardiac Surgery (ANH phase 3 https://t.co/VWWYwk9uqf

Jul 31, 2025 · 34 likes · 4 shares · 935,633 followers View post →
sana almana
@almana_sana · X

RT @rjotaduran: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co…

Jul 27, 2025 · 1 share · 105 followers View post →
Harmony
@Harmony85780462 · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease ミトコンドリア提供とmtDNA疾患の着床前遺伝子検査 2025.7.16 NEJM このように生命をいじくり自然の摂理を無視することは果たして倫理にかなうのか? https://t.co/n5Gm544Zlz

Jul 27, 2025 · 134 followers View post →
Richard Jonathan O Taduran
@rjotaduran · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/va02HsOFIn

Jul 26, 2025 · 1 like · 1 share · 347 followers View post →
STITCHES Medicine - the Best of Medical Research
@medicine.stitches.today · Bluesky

Mitochondrial donation successfully reduced harmful mtDNA variants, resulting in healthy live births for affected women. by Hyslop LA, Blakely EL (...) Herbert M et 28 al. in N Engl J Med #MedSky

Jul 25, 2025 · 8 likes · 3 shares View post →
STITCHES Medicine - the Best of Medical Research
@STITCHESMed · X

Mitochondrial donation successfully reduced harmful mtDNA variants, resulting in healthy live births for affected women. by Hyslop LA, Blakely EL (...) Herbert M et 28 al. in N Engl J Med https://t.co/CKG9ZYlNJD #MedX #MedResearch

Jul 25, 2025 · 83 followers View post →
Martin Michaelis
@MartMichaelis · X

The beginning of the end of mitochondrial disease? We only make progress, if we invest in #research... https://t.co/ZLCjRWTtSO

Jul 23, 2025 · 406 followers View post →
Sarah Mitchell
@PolicySteps · X

RT @BowTiedBiotech: Maybe not so crazy after all....in NEJM this week: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA…

Jul 23, 2025 · 1 share · 28 followers View post →
BowTiedBiotech
@BowTiedBiotech · X

Maybe not so crazy after all....in NEJM this week: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease Kind of mind blowing - mitochondrial implants saving pregnancies.... Need to keep a close eye on the mitochondrial space - it is a new frontier with https://t.co/0ON3jBVFXr https://t.co/JQaZIXbofs

Jul 23, 2025 · 1 like · 1 share · 20,608 followers View post →
Saludteca
@Saludteca · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/PGTWnL3vgC

Jul 22, 2025 · 2,000 followers View post →
不妊と手術.com
@hunintosyujyutu · X

間違いなく、今後ミトコンドリア病に対する前核移植やPGTは増えるだろうと思わせる報告でした。。。 Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/6o8aFNaPzC

Jul 21, 2025 · 6 likes · 1,593 followers View post →
Guy-Stone, MD, MPH
@MPH_Stone · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 21, 2025 · 20 shares · 600 followers View post →
M. Victoria Delpino
@victuare · X

RT @_CVasilescu: #MitochondrialDisease selection of papers from #week29!

Jul 21, 2025 · 4 shares · 23 followers View post →
the paper link
@the_paper_link · X

Trend up+73: Hyslop LA, ..., Herbert M (N Engl J Med) __Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease__ https://t.co/V8Wjcn202a

Jul 21, 2025 · 137 followers View post →
Dr. Gennadi Glinsky, MD, Ph.D.
@gglinskii · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/ksJaLlx9FU

Jul 20, 2025 · 2,065 followers View post →
MitoSociety
@MitoSociety · X

RT @_CVasilescu: #MitochondrialDisease selection of papers from #week29!

Jul 20, 2025 · 4 shares · 202 followers View post →
Keshav K Singh, PhD
@mitoscientist · X

RT @_CVasilescu: #MitochondrialDisease selection of papers from #week29!

Jul 20, 2025 · 4 shares · 1,165 followers View post →
Newyork Fitness
@NewYorkPass · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 20, 2025 · 17 shares · 4,772 followers View post →
Sajal Malik
@maliksajal1 · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/w13qQmsfXI

Jul 20, 2025 · 69 followers View post →
Cristina Sánchez
@happyheartmed · X

RT @VivekSubbiah: ⭐️Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://…

Jul 20, 2025 · 3 shares · 17 followers View post →
Liam Campbell
@liambiotech · X

RT @VivekSubbiah: ⭐️Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://…

Jul 20, 2025 · 3 shares · 17 followers View post →
Gavin McStay
@gavinmcstay2 · X

RT @_CVasilescu: #MitochondrialDisease selection of papers from #week29!

Jul 20, 2025 · 4 shares · 2,190 followers View post →
Vivek Subbiah, MD
@VivekSubbiah · X

⭐️Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/gMMb5P9yg4

Jul 20, 2025 · 6 likes · 3 shares · 38,764 followers View post →
Catalina Vasilescu, PhD
@cvasilescu.bsky.social · Bluesky

#MitochondrialDisease selection of papers from #week29!

Jul 20, 2025 · 19 likes · 10 shares View post →
Catalina Vasilescu, PhD
@_CVasilescu · X

#MitochondrialDisease selection of papers from #week29!

Jul 20, 2025 · 12 likes · 4 shares · 1,049 followers View post →
Thoa Ha, MD
@ThoaHaMD · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 447 followers View post →
YA_UE
@yakuza7_YU · X

RT @takatoh_life: 【原著論文1】 Louise A. Hyslop, et al. "Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" New Engla…

Jul 19, 2025 · 2 shares · 199 followers View post →
bxFLgfubBCvHa5B
@bxFLgfubBCvHa5B · X

RT @takatoh_life: 【原著論文1】 Louise A. Hyslop, et al. "Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" New Engla…

Jul 19, 2025 · 2 shares · 1,105 followers View post →
Online Pharmacy
@PharmacyOnline8 · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 6,259 followers View post →
Daniel Hammersley
@drdanhamm · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 405 followers View post →
Dr. Gilberto Pérez López MD PhD
@Endocrino_PED · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 4,773 followers View post →
Abstream
@abstreamme · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease #science #publication #research #publications https://t.co/aQHCtk7IYW

Jul 19, 2025 · 787 followers View post →
ملتقى علوم الاحياء
@Biology1802 · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 54,625 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 182 followers View post →
Fritz Wagner
@codenchatai · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 18 followers View post →
高遠 頼@生命科学VTuber(たかとー らい) 定期科学ニュース配信(日)
@takatoh_life · X

【原著論文1】 Louise A. Hyslop, et al. "Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" New England Journal of Medicine, Published online: July 16, 2025 https://t.co/DhSzI1rFAd

Jul 19, 2025 · 3 likes · 2 shares · 13,633 followers View post →
Fourth Grace
@EuphrosMD · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 26 followers View post →
Dr Karima Zitouni
@K_Zitouni_PhD · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 38 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 19, 2025 · 17 shares · 32,536 followers View post →
Rajeev Chitguppi
@chitguppi · X

https://t.co/qenU2aqrAI

Jul 18, 2025 · 2,798 followers View post →
Dr. Gennadi Glinsky, MD, Ph.D.
@gglinskii · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine. https://t.co/ksJaLlx9FU

Jul 18, 2025 · 2,065 followers View post →
Candice Chan
@emergingbugs · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 18, 2025 · 17 shares · 62 followers View post →
Robert Howard also on BlueSky as @ProfRobHoward
@ProfRobHoward · X

RT @NEJM: Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article:…

Jul 18, 2025 · 17 shares · 17,994 followers View post →
NEJM
@NEJM · X

Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Science behind the Study: Advances in https://t.co/u3MO2sHffT

Jul 18, 2025 · 57 likes · 17 shares · 935,633 followers View post →
Le Tran Phuc Khoa
@LeTranPhucKhoa1 · X

RT @NEJM: Women with homoplasmic variations in mitochondrial DNA are at high risk for having affected biologic children. This study tests a…

Jul 18, 2025 · 7 shares · 264 followers View post →
Joseph Marine
@DrJMarine · X

NEJM article 2: https://t.co/EaTsXWLIWR

Jul 18, 2025 · 1 like · 10,696 followers View post →
ShorterLab
@ShorterLab · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/ulO7Zawtkk

Jul 18, 2025 · 1 like · 1 share · 12,042 followers View post →
Le Tran Phuc Khoa
@LeTranPhucKhoa1 · X

RT @bloodgenes: Wow!!! Big advance for women with pathogenic mitochondrial DNA variants in @NEJM! https://t.co/PUZMkbx2sr https://t.co/Z…

Jul 18, 2025 · 5 shares · 264 followers View post →
Johns Hopkins Frailty Science #FrailtyFighter
@FrailtyScience · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 2,270 followers View post →
Dr Abeer Kartikey
@GuptaAbeer · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 343 followers View post →
SANDRAJOHNSTON
@sandra04850184 · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 943 followers View post →
C. Michael Gibson MD
@CMichaelGibson · X

Mitochondrial donation through pronuclear transfer is compatible with human embryo viability and reduces the transmission of pathogenic #mitochondrial DNA. Levels of the maternal pathogenic mtDNA were 95 -100% lower in 6 kids & 77 to 88% lower in 2. https://t.co/v5DRsXxK3H

Jul 18, 2025 · 8 likes · 1 share · 432,151 followers View post →
PharmaDecisions LLC
@PharmaDecisions · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 453 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 182 followers View post →
Nadim Darwich
@ndgenomics · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 15 followers View post →
Dieter
@Wuhle · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 475 followers View post →
Saubashya Sur, PhD
@SaubashyaSur · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 768 followers View post →
Komla Delali Asorgoe, M.D.
@KomlaDDAsorgoe · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 317 followers View post →
Sara Gutiérrez-Enríquez
@SaraGutierrezEn · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 18, 2025 · 51 shares · 722 followers View post →
Purificació Barceló
@pjbarc · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 18, 2025 · 51 shares · 1,285 followers View post →
Theriaque_officiel
@Theriaque_CNHIM · X

Première validation de la technique d'AMP avec don de mitochondries pour éviter des maladies mitochondriales. https://t.co/tdwVkzF1dD https://t.co/EV63V68Xb1

Jul 18, 2025 · 1,789 followers View post →
おだQ
@OdaQ_DM · X

元論文はこちらです きょうみあるかたはどうぞ Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease. New England Journal of Medicine. doi:10.1056/NEJMoa2415539 https://t.co/HHemqIzjEw

Jul 18, 2025 · 11 likes · 15,254 followers View post →
Wei-Guo Ma, MD
@Dr_Ma_of_PUMC · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 2,369 followers View post →
Dr. Sue Gross
@DrSueGross · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 3,031 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 18, 2025 · 20 shares · 32,536 followers View post →
Dr Shweta Kaul jha
@skauljha · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/LRelaJgtYI Wired weekends #Modern technology in OBGYN

Jul 17, 2025 · 50 followers View post →
emilio lindosa lucas
@411emilio · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 4,855 followers View post →
♬∞Punch♏︎Tsubasa☉☯
@PunchSakura · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 17, 2025 · 20 shares · 70 followers View post →
Yuta Asano
@yutaAsano1991 · X

ミトコンドリアDNAに異常を持つ女性が子供に影響を残さないよう、受精卵の核を正常なミトコンドリアDNAを持つ別の女性由来の受精卵に移植して出産。すげーな。 Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/4ZBcmm9sS7

Jul 17, 2025 · 187 followers View post →
Eduart Montes
@EduartMontes · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 1,125 followers View post →
GreenDoc Gwen
@ecogwendoc · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 17, 2025 · 20 shares · 24 followers View post →
Ginger Edwin
@GingerMEdwin · X

Mitochondrial donation through pronuclear transfer compatible with human embryo viability. Both pronuclear transfer and PGT were effective in reducing the transmission of homoplasmic and heteroplasmic pathogenic mtDNA variants. https://t.co/O1AmTp514f

Jul 17, 2025 · 1,300 followers View post →
Saber Atualizado
@AtualizadoSaber · X

(2) Publicação dos estudos: https://t.co/H7BaMwFi0b https://t.co/XGQkSIBpSF > Referência adicional: https://t.co/AieRMlrzib

Jul 17, 2025 · 10 likes · 30,182 followers View post →
Dra Chispas
@ChispasDra · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 226 followers View post →
Wimen
@1a31551c566e43d · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 17, 2025 · 20 shares · 664 followers View post →
Marta Hernández
@MartadeMarte · X

RT @NEJM: Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Re…

Jul 17, 2025 · 20 shares · 751 followers View post →
NEJM
@NEJM · X

Original Article: Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease https://t.co/RZBIm2yak5 Brief Report: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease https://t.co/DDDGpiljkt Science behind the Study: Advances in https://t.co/T1BMSiil8B

Jul 17, 2025 · 54 likes · 20 shares · 935,633 followers View post →
Sara Cuevas Ocaña
@SaraOcana1 · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 462 followers View post →
MEducationPublication
@MEducationPub · X

RT @NEJM: Women with homoplasmic variations in mitochondrial DNA are at high risk for having affected biologic children. This study tests a…

Jul 17, 2025 · 7 shares · 200 followers View post →
C. Delgado ☯️
@cris_pitita · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 125 followers View post →
GECYEN
@GECYEN_UNIOVI · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 233 followers View post →
J
@gradot_neubav · X

@mkrobot @procesorot @__aloines_ Донорска mtDNA. Кај нив е легално цела декада, но пробивот е изгледа направен во скоро време. Да се живи и здрави дечињата. Овде е целата студија: https://t.co/aDdQdsrZHh

Jul 17, 2025 · 182 followers View post →
Lluis Montoliu
@LluisMontoliu · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 38,256 followers View post →
Ma*do final season
@halocito · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 217 followers View post →
Sombradoble
@sombradoble · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 11,808 followers View post →
旅人 tabito
@tabibito250 · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/RamWHFOGDq

Jul 17, 2025 · 1,075 followers View post →
Cecelia Care ♥️
@ceceliacare.bsky.social · Bluesky

"Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" #Caregiving #Healthcare #ElderCare #MedSky

Jul 17, 2025 View post →
Cecelia Care ♥️
@ceceliacare.bsky.social · Bluesky

"Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" #Caregiving #Healthcare #ElderCare #MedSky

Jul 17, 2025 View post →
Cecelia Care ♥️
@ceceliacare.bsky.social · Bluesky

"Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" #Caregiving #Healthcare #ElderCare #MedSky

Jul 17, 2025 View post →
Cecelia Care ♥️
@ceceliacare.bsky.social · Bluesky

"Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" #Caregiving #Healthcare #ElderCare #MedSky

Jul 17, 2025 View post →
Cecelia Care ♥️
@ceceliacare.bsky.social · Bluesky

"Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" #Caregiving #Healthcare #ElderCare #MedSky

Jul 17, 2025 View post →
Cecelia Care ♥️
@ceceliacare.bsky.social · Bluesky

"Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" #Caregiving #Healthcare #ElderCare #MedSky

Jul 17, 2025 · 1 like View post →
Cecelia Care ♥️
@ceceliacare.bsky.social · Bluesky

"Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" #Caregiving #Healthcare #ElderCare #MedSky

Jul 17, 2025 View post →
Cecelia Care ♥️
@ceceliacare.bsky.social · Bluesky

"Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" #Caregiving #Healthcare #ElderCare #MedSky

Jul 17, 2025 View post →
Cecelia Care ♥️
@ceceliacare.bsky.social · Bluesky

"Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease" #Caregiving #Healthcare #ElderCare #MedSky

Jul 17, 2025 View post →
JORGE GARCIA
@GeorgusCayo · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 752 followers View post →
vt-sci-ctzn.bsky.social
@vt-sci-ctzn.bsky.social · Bluesky

For the hardcore among us: Hyslop LA et al. Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease. NEJM. doi:10.1056/NEJMoa2415539; McFarland R et al. Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease. NEJM. doi:10.1056/NEJMoa2503658. Online 20250716.

Jul 17, 2025 View post →
Omar Cauli
@CauliOmar85563 · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 81 followers View post →
Andy_Weeble_Weaver
@AndrewW66619812 · X

The first paper in "NEJM" the above "Nature" article is based upon, & links to: “Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease” 2/3 https://t.co/xfhDjn0C90

Jul 17, 2025 · 4,318 followers View post →
Dr. Bishoy M. Faltas
@FaltasLab · X

RT @bloodgenes: Wow!!! Big advance for women with pathogenic mitochondrial DNA variants in @NEJM! https://t.co/PUZMkbx2sr https://t.co/Z…

Jul 17, 2025 · 5 shares · 7,422 followers View post →
Alejandro De Los Angeles, DPhil, MPH
@delosangeles520 · X

RT @NEJM: Women with homoplasmic variations in mitochondrial DNA are at high risk for having affected biologic children. This study tests a…

Jul 17, 2025 · 7 shares · 89 followers View post →
Alejandro De Los Angeles, DPhil, MPH
@delosangeles520 · X

RT @bloodgenes: Wow!!! Big advance for women with pathogenic mitochondrial DNA variants in @NEJM! https://t.co/PUZMkbx2sr https://t.co/Z…

Jul 17, 2025 · 5 shares · 89 followers View post →
Olga
@norolga48 · X

RT @manuelmuro5: Donación mitocondrial por transferencia pronuclear es compatible con la viabilidad embrionaria. Un programa de transferenc…

Jul 17, 2025 · 1 share · 213 followers View post →
Manuel Muro
@manuelmuro5 · X

Donación mitocondrial por transferencia pronuclear es compatible con la viabilidad embrionaria. Un programa de transferencia pronuclear y test pre-implantacional fue eficaz para reducir la transmisión de variantes patógenas homo y heteroplásmicas del ADNmt https://t.co/BNiDeJTXli

Jul 17, 2025 · 5 likes · 1 share · 11,200 followers View post →
Lorena Villa García
@lore_efyc · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 4,877 followers View post →
Juana María Madrid
@Juanamariabio · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 1,141 followers View post →
SaraBioGeo
@sarabiogeo · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 106 followers View post →
Enrique Ayuso
@enriqueayuso · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 2,281 followers View post →
Eugenia Trigoso Arjona
@TrigosoArjona · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 29 followers View post →
Cristina Montserrat
@Crismon1007 · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 122 followers View post →
MadeinUruguay
@araucaria1 · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 2,339 followers View post →
Lara Wahlster
@LWahlster · X

RT @bloodgenes: Wow!!! Big advance for women with pathogenic mitochondrial DNA variants in @NEJM! https://t.co/PUZMkbx2sr https://t.co/Z…

Jul 17, 2025 · 5 shares · 579 followers View post →
@SEGenetica
@segenetica · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 2,332 followers View post →
Patricia Pedrosa
@PPH2609 · X

RT @LluisMontoliu: Reportan en @NEJM el nacimiento de 8 bebés sanos de madres portadoras de #mitocondrias con mutaciones gracias a la técni…

Jul 17, 2025 · 51 shares · 170 followers View post →
Professor Erwin Loh
@erwinloh · X

Sources: https://t.co/aORB1VfpQL https://t.co/mhioSCtiMt

Jul 17, 2025 · 10,404 followers View post →
matiere*
@matiere · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/0FrHSSC6HB

Jul 17, 2025 · 2,831 followers View post →
Dylan Ryan
@RyanLab_TCD · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/4jYthxu7mE

Jul 17, 2025 · 2,376 followers View post →
Ahmet Hasaligil
@ahmethasaligil.bsky.social · Bluesky

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine share.google/lMei7ksxIJT4...

Jul 17, 2025 View post →
あすとれいや
@astray_yatu · X

Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease | New England Journal of Medicine https://t.co/AtLhpFJWBn

Jul 17, 2025 · 221 followers View post →
Awesomics
@Awesomics · X

Pronuclear transfer

Jul 16, 2025 · 6,734 followers View post →
NEJM.org
@nejm.org · Bluesky

Jul 16, 2025 · 2 likes View post →
Science Media Centre UK
@smclondon.bsky.social · Bluesky

expert reaction to two papers on the use of mitochondrial donation and preimplantation genetic testing for mitochondrial disease, as published in NEJM www.sciencemediacentre.org/expert-react...

Jul 16, 2025 View post →