#Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilies influencing early human development and primate evolution. @ScienceAdvances https://t.co/CMaat4iyxt https://t.co/uWWMS5ysU2
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage.
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AI synopsis
What people are saying
Several discussions highlight how this research uncovers previously hidden roles of ancient viral DNA, describing it as a 'powerful switch' controlling gene activity, which reflects excitement about new understandings of genome regulation. The tone ranges from neutral to enthusiastic, with words like 'reveals,' 'uncover,' and 'powerful' emphasizing the perceived importance and potential for advancing genetics and evolutionary biology.
Most discussions acknowledge the significance of the research, with some participants emphasizing the discovery of new subfamilies and their relevance to understanding primate evolution.
Posts show high curiosity, particularly regarding the implications of endogenous retroviruses in gene regulation and primate biology, evidenced by phrases like 'powerful switch' and 'hidden regulatory roles.'
Participants demonstrate moderate engagement, referencing specific methods, such as the phylogenetic approach, and the potential functional insights, though most comments are supportive rather than deeply analytical.
The discussions suggest that the findings are perceived as potentially impactful, especially given comments about 'unlocking genome secrets' and the revision of previous notions about 'junk DNA,' indicating recognition of evolving impact in genetics.
Abstract in brief
- This study developed a new phylogenetic-based method to better classify and annotate endogenous retroviruses (ERVs) and their LTRs, overcoming limitations of previous approaches.
- The researchers identified four new subfamilies of young LTR elements (MER11ABC) and validated their regulatory functions using experimental assays, revealing motifs linked to differences in activity, including ape-specific genetic changes.
- Applying their method to 53 primate-related LTR subfamilies, they discovered 75 new subfamilies, refining the annotation of thousands of ERV elements, which can help clarify their roles in primate genome evolution and biology.
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Ancient viruses embedded in our DNA appear to help switch genes on and off A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage https://t.co/xMWnXdgmsY
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"A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage"
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Ancient viruses embedded in our DNA appear to help switch genes on and off A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage
RT @Progenics_labs: Ancient viral DNA once called “junk” is a powerful switch controlling early human development. MER11 elements shape wha…
Ancient viral DNA once called “junk” is a powerful switch controlling early human development. MER11 elements shape what makes us unique by regulating genes. Read: https://t.co/G8HbLfwZ5W Visit: https://t.co/9dKQYjHD5c #ViralDNA #genomicsisglobal #geneticdiscovery #progenics https://t.co/yZFD2d9ix0
Science Advances https://t.co/JTwg9uaQOt
"A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage"
@TakaInoue5 @xunchen85 @ScienceAdvances プレスリリースはこちら➡️ https://t.co/YVS7XQnDYh 論文はこちら➡️ https://t.co/t9aJGtFf44
Unlocking Primate Genome Secrets: New ERV/LTR Insights, published in Science Advances by Xun Chen et al: https://t.co/m10auSjdWL ➡ Our ViroMag R/L transduction reagent was used to transduce WTC11 human iPSCs cells with Lentivirus.
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage | Science Advances https://t.co/t8Q5y4O7RO Science Advances 18 Jul 2025 Vol 11, Issue 29
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage | Science Advances https://t.co/aWLGiqD1d1
https://t.co/4j9AHxUEXF
https://t.co/dQxfA1PhOg https://t.co/wdcrXlUxtA
Ancient viruses embedded in our DNA help switch genes on and off, study finds | Live Science www.livescience.com/health/genet... A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage | Science Advances www.science.org/doi/10.1126/... #openaccess
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage - https://t.co/w7gGGNF7eV
ARTÍCULO REFERENCIA (acceso abierto) A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage https://t.co/FRGvOmnqdn vía @ScienceAdvances
RT @OleksandrKashu2: A phylogenetic approach reveals cryptic LTR subfamilies and functional insights at nucleotide resolution in primates.…
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage www.science.org/doi/10.1126/...
A phylogenetic approach reveals cryptic LTR subfamilies and functional insights at nucleotide resolution in primates. Science Advances https://t.co/0Lwnprddks
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage https://t.co/AwUcjddKnb
Xun Chen et al. ,A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage.Sci. Adv.11,eads9164(2025).DOI:10.1126/sciadv.ads9164 https://t.co/noogVDDijh
@DivinelyDesined (1) This is a press release, which you paraphrased in a VERY biased manner; the conclusion is yours, not the authors,; highlighted comments challenge creationism (2) MER11 sequence is young, likely entered primate genomes 40 My ago. https://t.co/4FlDJSbuAz https://t.co/IWWQuKdb9B https://t.co/eo72tnCjLa
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage www.science.org/doi/10.1126/...
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage https://t.co/xMWnXdgmsY
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【PDF】Direct Link A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage https://t.co/nNzZjNDLnd
【プレスリリース】機能から見るトランスポゾン新分類法の開発 古代にゲノムへ取り込まれたウイルス由来遺伝子の機能解明を目指して | 日本の研究.com https://t.co/E7JsyG833R 元論文 A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage | Science
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
RT @physorg_com: #Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilie…
#Ancient viral DNA once labeled as "junk" is now shown to regulate #GeneExpression, with newly classified MER11 subfamilies influencing early human development and primate evolution. @ScienceAdvances https://t.co/CMaat4iyxt https://t.co/uWWMS5ysU2
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage https://pubmed.ncbi.nlm.nih.gov/40680142/
"Study reveals hidden regulatory roles of 'junk' DNA" [https://t.co/JcipQeZGF1] The "peer-reviewed paper behind this article [https://t.co/TboR3p8lun] is (currently) OPEN ACCESS. Calling it "junk DNA" was STUPID. IMO. https://t.co/JcipQeZGF1
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage https://pubmed.ncbi.nlm.nih.gov/40680142/
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage Science Advances https://t.co/Gn7yuQ3IRR
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage Science Advances www.science.org/doi/10.1126/...
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