Impact of embryo transfer strategies on children health outcomes: a retrospective national cohort study in Taiwan.

Abstract in brief

• The study examined how different assisted reproductive technology (ART) embryo transfer methods—specifically fresh versus frozen and cleavage versus blastocyst stages—affect the health of children in their early years, using data from Taiwan's national database.
• Results showed that children conceived through ART had higher rates of health issues such as ADHD, developmental delays, and preterm birth compared to naturally conceived children, but there were no significant differences based on the specific embryo transfer techniques used.
• The findings suggest that the increased health risks might be more related to parental infertility factors rather than the ART procedures themselves, highlighting the importance of improving ART protocols and perinatal care to better support these children's health.]