J Transl Med August 2025 PMID 40764934

Iron biomarkers in men with infertility are associated with sperm DNA hydroxymethylation and cumulative live birth rates: a prospective study.

Georges Raad, Fatima Husseiny, Zalihe Yarkiner, Valerie Grandjean, Marwa Bazzi, Marilyne Rizk, Fadi Fakih, Youmna Mourad, Chadi Fakih

Mentions

10
Peak: 8 in Aug 2025
across 3 sources since Aug 2025

Extended reach

2,905
potential audience

Total likes

3

Video views

270

Mentions per month

Aug 2025

All 8 dated mentions so far are from Aug 2025.

Where it's discussed

  • X / Twitter6 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The discussions show strong alignment with the publication's importance in understanding male fertility, with examples like referencing the 'FeRTILITY series,' emphasizing the link between iron and epigenetics, and using impactful language such as 'game changer' and 'health matters.' The tone and wording suggest high interest and perceived influence on reproductive health understanding.

AgreementModerate agreement

Most discussions acknowledge the importance of the research findings, emphasizing the role of iron in fertility outcomes and broadly supporting the conclusions about iron biomarkers' relevance.

InterestHigh interest

Posts reflect a high level of curiosity, with explicit mentions of topics like epigenetics, sperm health, and reproductive success, demonstrating engagement with the scientific content.

EngagementHigh engagement

Many comments specifically reference the article and related content, with some sharing links or highlighting chapters, indicating substantial involvement and reflection on the study's implications.

ImpactHigh impact

The discussions suggest the research could influence future fertility treatments or public health messages, especially given phrases like 'must consider' and 'game changer' to highlight significance.

Abstract in brief

  • The study found that higher levels of iron biomarkers, such as serum iron, TIBC, and seminal fluid iron, are positively correlated with increased sperm DNA hydroxymethylation (5hmC), which is linked to better sperm quality.
  • Elevated serum TIBC and seminal fluid iron are associated with higher cumulative live birth rates (CLBR) in men undergoing ICSI treatment, suggesting iron homeostasis plays a role in reproductive success.
  • The results highlight that maintaining proper iron levels may influence sperm DNA modifications and improve pregnancy outcomes, although further research is needed to fully understand these relationships.]

Top posts

Most liked on X and Bluesky
Dr. Georges Raad
@Dr_Georges_Raad · X

Check out Chapter 1 of the FeRTILITY series from our new article! Iron, fertility & epigenetics https://t.co/V3yAsHN0bd #Iron #MaleFertility #SpermHealth #Epigenetics #FeRTILITY #HealthMatters

Aug 11, 2025 · 479 followers View post →
Dr. Georges Raad
@Dr_Georges_Raad · X

Check out Chapter 1 of the FeRTILITY series from our new article! Iron, fertility & epigenetics https://t.co/V3yAsHNy0L #Iron #MaleFertility #SpermHealth #Epigenetics #FeRTILITY #HealthMatters

Aug 11, 2025 · 479 followers View post →
Dr. Georges Raad
@Dr_Georges_Raad · X

Did you know too much or too little iron can affect fertility?

Aug 18, 2025 · 479 followers View post →
Dr. Georges Raad
@Dr_Georges_Raad · X

Aug 26, 2025 · 479 followers View post →
Dr. Georges Raad
@Dr_Georges_Raad · X

Aug 6, 2025 · 1 share · 479 followers View post →
Shivani Scientific
@ShivaniIVF · X

Iron biomarkers in men with infertility are associated with sperm DNA hydroxymethylation and cumulative live birth rates: a prospective study - Journal of Translational Medicine - https://t.co/H8iQ7ikWiH https://t.co/SWB2SehNyb

Aug 6, 2025 · 239 followers View post →

All mentions

Dr. Georges Raad
@Dr_Georges_Raad · X

Aug 26, 2025 · 479 followers View post →
Dr. Georges Raad
@Dr_Georges_Raad · X

Did you know too much or too little iron can affect fertility?

Aug 18, 2025 · 479 followers View post →
Dr. Georges Raad
@Dr_Georges_Raad · X

Check out Chapter 1 of the FeRTILITY series from our new article! Iron, fertility & epigenetics https://t.co/V3yAsHN0bd #Iron #MaleFertility #SpermHealth #Epigenetics #FeRTILITY #HealthMatters

Aug 11, 2025 · 479 followers View post →
Dr. Georges Raad
@Dr_Georges_Raad · X

Check out Chapter 1 of the FeRTILITY series from our new article! Iron, fertility & epigenetics https://t.co/V3yAsHNy0L #Iron #MaleFertility #SpermHealth #Epigenetics #FeRTILITY #HealthMatters

Aug 11, 2025 · 479 followers View post →
Dr. Georges Raad
@Dr_Georges_Raad · X

Aug 6, 2025 · 1 share · 479 followers View post →
Shivani Scientific
@ShivaniIVF · X

Iron biomarkers in men with infertility are associated with sperm DNA hydroxymethylation and cumulative live birth rates: a prospective study - Journal of Translational Medicine - https://t.co/H8iQ7ikWiH https://t.co/SWB2SehNyb

Aug 6, 2025 · 239 followers View post →