ACS Nano August 2025 PMID 40788688

Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at the Subfemtomolar Level.

Yeji Choi, Seyedsina Mirjalili, Md Ashif Ikbal, Sean McClure, Maziyar Kalateh Mohammadi, Scott Clemens, Jose Solano, John Heggland, Tingting Zhang, Jiawei Zuo, Chao Wang

Mentions

35
Peak: 4 in Sep 2024
across 5 sources since Sep 2024

Extended reach

64,188
potential audience

Total likes

15

Video views

48

Mentions per month

Sep 2024 – Aug 2025

Where it's discussed

  • News23 articles
  • X / Twitter4 posts
  • Blogs4 articles
  • Bluesky2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions emphasize the significance of the new detection system, mentioning its rapid results, portability, and cost-effectiveness, with words like 'breakthrough' and 'transform' indicating enthusiasm. While many focus on the technological improvements, others highlight its potential to revolutionize disease diagnostics, showing both high interest and perceived impact with moderate levels of detailed engagement.

AgreementModerate agreement

Most discussions express strong support or enthusiasm for the research's potential, highlighting its advancements over existing methods.

InterestHigh interest

Posts demonstrate high interest, focusing on the technology's rapidity, sensitivity, and practical applications, often using phrases like 'breakthrough' and 'transformative'.

EngagementModerate engagement

Participants show moderate engagement by referencing specific technical details and implications for diagnostics, but some simply share links or brief comments.

ImpactHigh impact

The overarching tone suggests the publication could significantly influence rapid diagnostics, with phrases like 'game-changer' and emphasizing real-world applicability.

Abstract in brief

  • The study introduces a gold nanoparticle-supported electronic detection system called NasRED, which can rapidly identify SARS-CoV-2 antibodies and antigens with extremely high sensitivity at the subfemtomolar level.
  • Using engineered gold nanoparticles that bind specifically to the target proteins, NasRED produces easily observable color changes and can deliver results in just 15 minutes, outperforming traditional methods like ELISA in sensitivity.
  • The platform is simple, cost-effective, and suitable for point-of-care testing, as it doesn't require complex lab equipment or trained personnel, making it ideal for rapid diagnosis and screening in diverse biofluids.

Top posts

Most liked on X and Bluesky
ACS Nano
@acsnano · X

From a drop of sample to diagnosis within minutes, NasRED detects analytes at sub-femtomolar levels: a portable, low-cost breakthrough poised to transform infectious and chronic disease diagnostics. Read it here

Aug 14, 2025 · 13 likes · 6 shares · 42,315 followers View post →
bioRxiv Microbiology
@biorxiv_micrbio · X

Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at Attomolar Level https://t.co/P31fdBnIBS #biorxiv_micrbio

Sep 7, 2024 · 1 like · 2 shares · 20,831 followers View post →
Dr Anthony Martin
@AMAinsight · X

Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at the Subfemtomolar Level | ACS Nano https://t.co/NdFnKM5bvj

Aug 13, 2025 · 914 followers View post →
Jennifer Aniston
@Jenniferani0001 · X

RT @biorxiv_micrbio: Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at Attomolar Level http…

Sep 14, 2024 · 2 shares · 61 followers View post →
bioRxiv Microbiology
@biorxiv-microbiol.bsky.social · Bluesky

Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at Attomolar Level https://www.biorxiv.org/content/10.1101/2024.09.04.611305v1

Sep 7, 2024 View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at Attomolar Level https://www.biorxiv.org/content/10.1101/2024.09.04.611305v1

Sep 7, 2024 View post →

All mentions

ACS Nano
@acsnano · X

From a drop of sample to diagnosis within minutes, NasRED detects analytes at sub-femtomolar levels: a portable, low-cost breakthrough poised to transform infectious and chronic disease diagnostics. Read it here

Aug 14, 2025 · 13 likes · 6 shares · 42,315 followers View post →
Dr Anthony Martin
@AMAinsight · X

Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at the Subfemtomolar Level | ACS Nano https://t.co/NdFnKM5bvj

Aug 13, 2025 · 914 followers View post →
Jennifer Aniston
@Jenniferani0001 · X

RT @biorxiv_micrbio: Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at Attomolar Level http…

Sep 14, 2024 · 2 shares · 61 followers View post →
bioRxiv Microbiology
@biorxiv-microbiol.bsky.social · Bluesky

Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at Attomolar Level https://www.biorxiv.org/content/10.1101/2024.09.04.611305v1

Sep 7, 2024 View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at Attomolar Level https://www.biorxiv.org/content/10.1101/2024.09.04.611305v1

Sep 7, 2024 View post →
bioRxiv Microbiology
@biorxiv_micrbio · X

Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at Attomolar Level https://t.co/P31fdBnIBS #biorxiv_micrbio

Sep 7, 2024 · 1 like · 2 shares · 20,831 followers View post →