Nat Metab September 2025 PMID 40954286

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis.

Sunhee Jung, Hosung Bae, Won-Suk Song, Yujin Chun, Johnny Le, Yasmine Alam, Amandine Verlande, Sung Kook Chun, Joohwan Kim, Miranda E Kelly, Miranda L Lopez, Sang Hee Park, Daniel Onofre, Jongwon Baek, Ki-Hong Jang

Mentions

89
Peak: 62 in Sep 2025
across 7 sources since Sep 2025

Extended reach

342,775
potential audience

Total likes

7,326

Video views

140,501

Mentions per month

Sep 2025 – Nov 2025

Where it's discussed

  • X / Twitter55 posts
  • Facebook17 posts
  • News7 articles
  • Instagram4 posts
  • Bluesky3 posts
  • YouTube2 videos
  • Blogs1 articles

AI synopsis

What people are saying

Overall, the discussions demonstrate positive acknowledgment of the study's importance, with posts emphasizing the potential use of inulin to prevent fatty liver, like Nick Norwitz’s lateral thinking, and calling for exploration in humans. The tone is optimistic and focused on application, with words like 'promising,' 'exploring,' and 'potential' indicating both support and anticipation for future impact.

AgreementStrong agreement

Most discussions express strong support or enthusiasm for the findings, emphasizing the potential for dietary fibers like inulin to treat liver conditions.

InterestModerate interest

While some discussions show moderate interest by highlighting mechanisms and potential applications, others are more general, indicating curiosity rather than deep engagement.

EngagementModerate engagement

Several posts reference specific aspects of the research, such as gut microbiome changes and implications for human treatment, suggesting a moderate level of thoughtful participation.

ImpactModerate impact

Many users highlight the significance of the research, pointing to potential shifts in understanding or treatment of liver disease, indicating perceived high impact.

Abstract in brief

  • The study shows that when the gut microbiome adapts to dietary fiber inulin, it can break down fructose more effectively, reducing liver fat buildup and reversing conditions like insulin resistance and liver damage in male mice.
  • Inulin supplementation helps the small intestine process fructose before it reaches the liver, decreasing harmful fat production and preventing fructose from spilling over to the colon.
  • The beneficial effects are linked to changes in the gut microbiome, especially involving Bacteroides acidifaciens, which enhances the host’s ability to detoxify and protect the liver from fructose-induced damage.]

Top posts

Most liked on X and Bluesky
Nature Metabolism
@NatMetabolism · X

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 115 likes · 39 shares · 80,835 followers View post →
Walter Suárez Carmona
@a_fisiolog57853 · X

INULINA PARA EL TRATAMIENTO DE LA ESTEATOSIS HEPÁTICA: UNA VÍA A EXPLORAR EN HUMANOS ¡¡¡A leer, zagales!!! https://t.co/0tq3eksfn6 https://t.co/oQs1dcc9oX

Sep 26, 2025 · 29 likes · 4 shares · 4,198 followers View post →
Bruno Ramos-Molina, PhD
@Brunorm84 · X

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis #MASLD @NatMetabolism https://t.co/4OH16AJcIq

Sep 16, 2025 · 15 likes · 5 shares · 6,503 followers View post →
Agingdoc
@agingdoc1 · X

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis

Oct 15, 2025 · 8 likes · 3 shares · 43,178 followers View post →
Rene Sugar
@renesugar · X

@saffronandsky Small but mighty: inulin promotes small intestinal bacterial fructose feeding https://t.co/wpGt6Dlpjt Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/3bW06bu2Vy https://t.co/Xrtrzh5tPC

Sep 18, 2025 · 3 likes · 3,987 followers View post →
Christian Frezza
@frezzalab.bsky.social · Bluesky

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis www.nature.com/articles/s42...

Sep 16, 2025 · 2 likes · 2 shares View post →

All mentions

DeScAI agent
@longevity_agent · X

RT @agingdoc1: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis

Oct 16, 2025 · 3 shares · 757 followers View post →
NAD+
@madnadfit · X

RT @agingdoc1: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis

Oct 15, 2025 · 3 shares · 98 followers View post →
Mike
@Mike__4242 · X

RT @agingdoc1: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis

Oct 15, 2025 · 3 shares · 372 followers View post →
Agingdoc
@agingdoc1 · X

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis

Oct 15, 2025 · 8 likes · 3 shares · 43,178 followers View post →
Rachel
@Rachel_ERFF · X

@DoctorTro So what made me think laterally was our good friend and colleague Nick Norwitz. He was suggesting if you add inulin whilst eating fructose it prevents fatty liver. https://t.co/vKdYlmP6jZ. Have a read

Oct 11, 2025 · 104 followers View post →
bioenergeticbot
@bioenergeticbot · X

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/3JxgkuuEC5 Literature Review || DavidPS

Oct 10, 2025 · 1 like · 343 followers View post →
.c.a.r.l.o.s
@galantee28 · X

RT @a_fisiolog57853: INULINA PARA EL TRATAMIENTO DE LA ESTEATOSIS HEPÁTICA: UNA VÍA A EXPLORAR EN HUMANOS ¡¡¡A leer, zagales!!! https://t…

Sep 27, 2025 · 4 shares · 34 followers View post →
Koushik
@koushikphysio · X

RT @a_fisiolog57853: INULINA PARA EL TRATAMIENTO DE LA ESTEATOSIS HEPÁTICA: UNA VÍA A EXPLORAR EN HUMANOS ¡¡¡A leer, zagales!!! https://t…

Sep 27, 2025 · 4 shares · 519 followers View post →
Dr. Manuel Mendez
@manumenfer · X

RT @a_fisiolog57853: INULINA PARA EL TRATAMIENTO DE LA ESTEATOSIS HEPÁTICA: UNA VÍA A EXPLORAR EN HUMANOS ¡¡¡A leer, zagales!!! https://t…

Sep 26, 2025 · 4 shares · 213 followers View post →
Catalina Pogany
@pogany54 · X

RT @a_fisiolog57853: INULINA PARA EL TRATAMIENTO DE LA ESTEATOSIS HEPÁTICA: UNA VÍA A EXPLORAR EN HUMANOS ¡¡¡A leer, zagales!!! https://t…

Sep 26, 2025 · 4 shares · 684 followers View post →
Walter Suárez Carmona
@a_fisiolog57853 · X

INULINA PARA EL TRATAMIENTO DE LA ESTEATOSIS HEPÁTICA: UNA VÍA A EXPLORAR EN HUMANOS ¡¡¡A leer, zagales!!! https://t.co/0tq3eksfn6 https://t.co/oQs1dcc9oX

Sep 26, 2025 · 29 likes · 4 shares · 4,198 followers View post →
Ubong Ekperikpe, Ph.D.
@ubong_ekperikpe · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 19, 2025 · 39 shares · 362 followers View post →
HaylaKSluss
@HaylaSluss · X

RT @Brunorm84: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis #MASLD @NatMetabolism https://t.…

Sep 19, 2025 · 5 shares · 19 followers View post →
Nature Reviews Gastroenterology & Hepatology
@natrevgastrohep.nature.com · Bluesky

#GastroEdPick Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis @natmetabolism.nature.com www.nature.com/articles/s42...

Sep 19, 2025 View post →
Rene Sugar
@renesugar · X

@saffronandsky Small but mighty: inulin promotes small intestinal bacterial fructose feeding https://t.co/wpGt6Dlpjt Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/3bW06bu2Vy https://t.co/Xrtrzh5tPC

Sep 18, 2025 · 3 likes · 3,987 followers View post →
Carmen De Miguel, PhD, MS, FAHA
@Carmendemigue12 · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 18, 2025 · 39 shares · 3,375 followers View post →
Natalie Porat-Shliom
@PoratShliomLab · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 17, 2025 · 39 shares · 965 followers View post →
María Á. Núñez-Sánchez
@MANunezSanchez · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 17, 2025 · 39 shares · 192 followers View post →
Lum Lab
@lum_lab · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 17, 2025 · 39 shares · 1,201 followers View post →
Climate, Ecology, War & More- Dr Glen Barry, BigEarthData.ai
@bigearthdata.bsky.social · Bluesky

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis ->Nature | More info from BigEarthData.ai

Sep 17, 2025 View post →
Marcus Böhme
@BoehmeMarcus · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 17, 2025 · 39 shares · 4,314 followers View post →
Prof Sam El-Osta
@SamElOsta1 · X

RT @Brunorm84: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis #MASLD @NatMetabolism https://t.…

Sep 16, 2025 · 5 shares · 803 followers View post →
Hem Chandra Jha
@HemChan44904616 · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 16, 2025 · 39 shares · 278 followers View post →
iArmandoVBaneado
@iArmandoVBanned · X

RT @Brunorm84: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis #MASLD @NatMetabolism https://t.…

Sep 16, 2025 · 5 shares · 67 followers View post →
⚫️ลัคกี้⚡️
@sr_wiz · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 16, 2025 · 39 shares · 1,576 followers View post →
Carmen De Miguel, PhD, MS, FAHA
@Carmendemigue12 · X

RT @Brunorm84: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis #MASLD @NatMetabolism https://t.…

Sep 16, 2025 · 5 shares · 3,375 followers View post →
fabiohhto
@0xfabiosje · X

RT @Brunorm84: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis #MASLD @NatMetabolism https://t.…

Sep 16, 2025 · 5 shares · 1,308 followers View post →
Bruno Ramos-Molina, PhD
@Brunorm84 · X

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis #MASLD @NatMetabolism https://t.co/4OH16AJcIq

Sep 16, 2025 · 15 likes · 5 shares · 6,503 followers View post →
María R. Aburto
@isen_gard · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 16, 2025 · 39 shares · 1,825 followers View post →
Robertinho
@7Robertinho · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 16, 2025 · 39 shares · 304 followers View post →
Christian Frezza
@frezzalab.bsky.social · Bluesky

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis www.nature.com/articles/s42...

Sep 16, 2025 · 2 likes · 2 shares View post →
Amaya Lopez-Pascual
@amayalpzp · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 16, 2025 · 39 shares · 281 followers View post →
Tanusree Das
@TDbiochem · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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Herbs and Havoc
@HerbsAndHavoc · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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Rene Sugar
@renesugar · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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Katie Guzzetta
@ktguzz · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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Yunkyeong Lee
@yunkyeong_lee · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 114 followers View post →
Peter Dousma
@PHD2468 · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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Érique Castro
@eriquecaastro · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 323 followers View post →
Mingqi Han
@MingqiHan · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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SandyInhaca
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RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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@MaxCayllahua · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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TAATJENE Food Industries
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RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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@ABrayanCampos · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 1,627 followers View post →
Alessandro Carrer
@acarrer · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 917 followers View post →
Kate M.
@KateM000000 · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 160 followers View post →
Cholsoon Jang
@cholsoon_jang · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 1,049 followers View post →
Bowen Wang
@NU_JEANSS · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 274 followers View post →
Dr. Joshuan J. Barboza
@joshuanbarbozam · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 10,207 followers View post →
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@bibourokuabc · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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@PharmphoodTM · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 555 followers View post →
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@roeskandari · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 233 followers View post →
Marcus Goncalves
@MarcusDGon · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 2,663 followers View post →
Lyssiotis Lab
@LyssiotisLab · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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@MeghanConn01 · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 73 followers View post →
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@Tao_Zuo_ · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 39 shares · 498 followers View post →
Enjoy your life but Stay Alert!
@AlesandroSherry · X

RT @NatMetabolism: Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

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Nature Metabolism
@NatMetabolism · X

Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis https://t.co/dWPWcBzbVC

Sep 15, 2025 · 115 likes · 39 shares · 80,835 followers View post →
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... and reverses hepatic steatosis. Nat Metab (2025). https://doi.org/10.1038/s42255-025-01356-0 · Cindy Chen and 2 others ·

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... 10.1038/s41568-025-00807-w 3. 各公司官網&公開資料. Instagram. Log in ... org/10.1038/s42255-025-01356-0. more. 7 days ago · drugnews.com.tw's ...

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... 促進 #健康管理 · #健康生活型態 資料來源:https://doi.org/10.1038/s42255-025-01356-0. more. 2 days ago · gph.tsai's profile picture. gph.tsai. •.

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... microbiome clears dietary fructose and reverses hepatic steatosis. Nat Metab (2025). https://doi.org/10.1038/s42255-025-01356-0 ·

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全球公衛健康飲食生活型態|蔡秉兼公共衛生師added a new... - 全球 ...
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... 促進 #健康管理 #健康生活型態 資料來源:https://doi. org/10.1038/s42255-025-01356-0 · No photo description available. 陳貴玲 ·

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