PubHawk
ESC Heart Fail September 2025 PMID 40968746

SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI.

Marco Metra, Daniela Tomasoni, Marianna Adamo, Offer Amir, Stefan D Anker, Antoni Bayes-Genis, Michael Boehm, Javed Butler, Ovidiu Chioncel, Gerasimos Filippatos, Finn Gustafsson, Ewa A Jankowska, Juan Carlos Kaski, Brenda Moura, Mark C Petrie

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Mentions

35
Peak: 31 in Oct 2025
across 2 sources since Sep 2025

Extended reach

55,245
potential audience

Total likes

113

Video views

302

Mentions per month

Sep 2025 – Oct 2025

Where it's discussed

  • X / Twitter33 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions around this publication reflect a positive outlook, with posters emphasizing the significance of the research, such as references to 'expanded indications' and 'beneficial' effects, which demonstrate recognition of the potential clinical impact. The tone suggests an optimistic but cautious interest, as users refer to the study's role in guiding treatment strategies and guidelines, without expressing strong controversy or skepticism.

AgreementModerate agreement

Most discussions recognize the publication as an important advancement in treatment guidelines, with terms like 'expanded' and 'significant' indicating broad support for the findings.

InterestHigh interest

Posts demonstrate high curiosity by highlighting the broadening of clinical indications and emphasizing the relevance of the research, using words like 'further expands' and 'beneficial'.

EngagementModerate engagement

While some posts briefly mention the research outcomes, they do not delve deeply into methodology or future implications, reflecting moderate engagement.

ImpactModerate impact

Participants perceive the publication as impactful, noting implications for clinical practice and guidelines, but this is expressed more as acknowledgment than with calls for immediate change.

Abstract in brief

  • SGLT2 inhibitors, initially recommended for preventing and treating heart failure in patients with type 2 diabetes, have shown benefits across a broader spectrum, including HF with preserved ejection fraction, leading to expanded guidelines.
  • Studies like SOLOIST-HF, EMPULSE, and EMPACT-MI demonstrate that starting SGLT2 inhibitors early during or after acute heart failure episodes can be beneficial, but stopping treatment may quickly reduce their positive effects.
  • While observational reports suggest potential benefits of SGLT2 inhibitors in conditions such as cardiac amyloidosis, congenital heart disease, and pediatric heart failure, these findings require confirmation through future prospective clinical trials.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Ahmed Bennis MD
@drbennisahmed · X

SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The reduction in HF events with SGLT2is in patients with CKD and T2DM further expanded their indication for the prevention of HF in these patients @JavedButler1 https://t.co/P2e3Qmxe1U

Oct 12, 2025 · 94 likes · 29 shares · 2,974 followers View post →
宇津 貴史 /Utsu, Takashi
@Office_j · X

https://t.co/V9foCwsmyx

Sep 21, 2025 · 2 likes · 4,918 followers View post →
SGLT_Users
@SGLT_users · X

@JACCJournals @ESCardio @MountSinaiNYC @DLBHATTMD @Hragy @SantosGallegoMD @DukeVascular SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI - Metra - ESC Heart Failure https://t.co/yLhFfoRbgV

Oct 12, 2025 · 1 like · 20 followers View post →
Khalid Minhas, MD FACC
@minhaskh · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 11,360 followers View post →
Shelley Zieroth
@ShelleyZieroth · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 10,007 followers View post →
Dr. Hugo Corrales - Endocrinología.
@hugoendocrino · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 6,472 followers View post →

All mentions

CommunityRSC
@CommunityRSC · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 14, 2025 · 29 shares · 52 followers View post →
Juan Pedro Romero
@JuanPedroRome20 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 14, 2025 · 29 shares · 204 followers View post →
Philipp Lopatka
@LopatkaPhilipp · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 14, 2025 · 29 shares · 197 followers View post →
Dr. Álvaro Herrera E
@heralv1985 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 1,098 followers View post →
Nikhil Narang, MD
@Nikhil15 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 3,056 followers View post →
Daniel Velarde
@dvelarde85 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 613 followers View post →
Dr. Hugo Corrales - Endocrinología.
@hugoendocrino · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 6,472 followers View post →
myla capellan
@mdmyla · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 67 followers View post →
Blessing Muponda
@BMuponda · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 104 followers View post →
Elena Chover
@elechover · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 3,278 followers View post →
Natsir Ramadhan
@natsiradhan · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 562 followers View post →
Ivonne Torres-Atencio
@negrita73bn · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 2,377 followers View post →
Daniel Pita, MD
@danpita · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 13, 2025 · 29 shares · 1,312 followers View post →
Dr Drug Ph.D
@Dj70504283 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 113 followers View post →
Roberto Gutiérrez
@DrRobertoGuti · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 783 followers View post →
sheldon tobe
@sheldon_tobe · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 72 followers View post →
lal0155
@lal0155 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 13 followers View post →
Osama Louis
@OsamaLouis5 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 86 followers View post →
Gabriel Paredes, MD, FACC, FSSC
@gnparedes · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 362 followers View post →
Dr.AMiT JAiSWAL
@aadvikmedics · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 58 followers View post →
Sherif
@Sherifdotcom · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 133 followers View post →
Michele Emdin
@MicheleEmdin · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 1,013 followers View post →
Elham Elmehdawi
@Elham1549664 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 41 followers View post →
Umut Kocabaş
@UmutKocabasMD · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 1,474 followers View post →
Victor Hernández
@VicHdez27 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 144 followers View post →
Shelley Zieroth
@ShelleyZieroth · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 10,007 followers View post →
Sam
@spanday31 · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 285 followers View post →
SGLT_Users
@SGLT_users · X

@JACCJournals @ESCardio @MountSinaiNYC @DLBHATTMD @Hragy @SantosGallegoMD @DukeVascular SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI - Metra - ESC Heart Failure https://t.co/yLhFfoRbgV

Oct 12, 2025 · 1 like · 20 followers View post →
Khalid Minhas, MD FACC
@minhaskh · X

RT @drbennisahmed: SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The…

Oct 12, 2025 · 29 shares · 11,360 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI The reduction in HF events with SGLT2is in patients with CKD and T2DM further expanded their indication for the prevention of HF in these patients @JavedButler1 https://t.co/P2e3Qmxe1U

Oct 12, 2025 · 94 likes · 29 shares · 2,974 followers View post →
Kazuhiro Yokobatake
@k_yokoba · X

SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI - Metra - ESC Heart Failure - Wiley Online Library https://t.co/2bf4phvBuo

Sep 27, 2025 · 12 followers View post →
May wathan aung
@WathanA98824 · X

SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI - Metra - ESC Heart Failure - Wiley Online Library https://t.co/kpFpkgyvjr

Sep 27, 2025 · 2 followers View post →
宇津 貴史 /Utsu, Takashi
@Office_j · X

https://t.co/V9foCwsmyx

Sep 21, 2025 · 2 likes · 4,918 followers View post →