The discussions predominantly express strong agreement with the study’s results, citing specific figures like a 43% reduction in major cardiovascular events, and using words like 'huge effect' and 'excellent study,' which reflect high interest and perceived significance. The tone is optimistic and analytical, with many examples referencing the trial methodology and implications for treatment, indicating deep engagement and potential impact on clinical strategies.
AgreementModerate agreement
Most discussions support the positive findings of the study, emphasizing fish oil as a promising preventive measure against cardiovascular events in hemodialysis patients.
InterestHigh interest
The content generates high interest, with many posts highlighting the significance of the results and potential clinical applications.
EngagementHigh engagement
Posts actively discuss methodological details, such as the 4g daily dosage, reduced risk percentages, and trial comparisons, showing deep engagement.
ImpactHigh impact
The widespread sharing and focus on the study's promising outcomes suggest these discussions could influence clinical practices and future research on cardiovascular risk management.
Abstract in brief
Fish oil supplementation (4g daily containing EPA and DHA) in patients on hemodialysis significantly reduced the incidence of serious cardiovascular events over 3.5 years compared to a placebo.
The study found that the rate of cardiovascular events was about half in the fish oil group (hazard ratio 0.57), indicating a strong potential benefit of fish oil for this high-risk population.
The results suggest that fish oil may also decrease non-cardiac causes of death, with overall trends pointing towards a reduction in both cardiac and non-cardiac related deaths among patients receiving hemodialysis.]
PISCES: Among 1228 pts on HD, 4g omega-3 fatty acids vs corn oil placebo led to reduction in serious CV events (HR 0.57!). https://t.co/fJNeyKFWMk @NEJM
This is on the background of null STRENGTH (4g omega-3 carboxylic acids vs corn oil in high CV risk pts https://t.co/OMVtKa6u5D
Nov 9, 2025 · 67 likes · 15 shares · 25,717 followersView post →
腎
腎攻
@hama_nephro · X
【話題の透析患者への魚油
Nov 11, 2025 · 57 likes · 4 shares · 1,264 followersView post →
Nov 11, 2025 · 22 likes · 1 share · 21,492 followersView post →
NO
NEJM.org
@nejm.org · Bluesky
In the PISCES trial involving participants receiving hemodialysis, fish oil (n−3 fatty acids) was compared with corn-oil placebo. The rate of serious cardiovascular events was lower with daily fish-oil supplementation. Full trial results: nej.md/49zWuqo
@asnkidney.bsky.social | #KidneyWk
This video discusses recent research on left atrial appendage closure as a safe and effective alternative to anticoagulation in high-risk atrial fibrillation patients. It highlights reduced bleeding complications and…
Listener feedback on nonculprit PCI in STEMI and major cardiac findings in hemodialysis patients. Key studies include the PISCES, REDUCE-IT, and STRENGTH trials, highlighting recent developments in acute MI management…
Dr AnneLaure Faucon and Dr Marie Evans analyze epidemiological data on cardiovascular events and bleeding complications in advanced CKD patients from the Swedish Renal Registry, highlighting key findings and clinical…
Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis | New England Journal of Medicine https://t.co/M5qGTR39tU
Nov 22, 2025 · 1 like · 2,429 followersView post →
SR
STITCHES Medicine - the Best of Medical Research
@medicine.stitches.today · Bluesky
Fish-oil supplementation significantly reduces serious cardiovascular events in hemodialysis patients, suggesting a potent preventive strategy.
by Lok CE, Farkouh M (...) Udell JA et 6 al. in N Engl J Med #MedSky
Fish-oil supplementation significantly reduces serious cardiovascular events in hemodialysis patients, suggesting a potent preventive strategy.
by Lok CE, Farkouh M (...) Udell JA et 6 al. in N Engl J Med
https://t.co/2M9wPrMMgs #MedX #MedResearch
Nov 13, 2025 · 2 shares · 175 followersView post →
EH
Eduardo Hernández
@EduardoHn46 · X
Ensayo RCT demuestra que 4g/día de omega-3 reduce eventos cardiovasculares graves en pacientes en hemodiálisis, con 43% menos riesgo y buen perfil de seguridad.
Potencial intervención clave en prevención de riesgo cardiovascular en #Nefrología.
NEJM DOI: 10.1056/NEJMoa2513032 https://t.co/uxfMOqxcsp
Nov 11, 2025 · 22 likes · 1 share · 21,492 followersView post →
腎
腎攻
@hama_nephro · X
【話題の透析患者への魚油
Nov 11, 2025 · 57 likes · 4 shares · 1,264 followersView post →
RL
rin-co-ln
@rin_coln_ · X
RT @Ryu04196650Ryu: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis PISCE trial
ASN Kidney Weekから同時掲載…
Nov 11, 2025 · 13 shares · 388 followersView post →
YK
Y Kano
@ykano21 · X
secondaryだけど全死亡には差がついていなくて、逆に良かったねというような話もした。なぜ良いのかということについては書かないけれど。
でもNを増やせば、そこも有意差がつきそうではある。
Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis | New England
Nov 11, 2025 · 1 like · 1,753 followersView post →
RG
Roberto Gutiérrez
@DrRobertoGuti · X
RT @pnatarajanmd: PISCES: Among 1228 pts on HD, 4g omega-3 fatty acids vs corn oil placebo led to reduction in serious CV events (HR 0.57!)…
Nov 10, 2025 · 15 shares · 785 followersView post →
OS
Oliver Shannon
@Oli_Shannon · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 10, 2025 · 84 shares · 889 followersView post →
Mن
Matt Tabinor ن
@Tabsinator · X
RT @pnatarajanmd: PISCES: Among 1228 pts on HD, 4g omega-3 fatty acids vs corn oil placebo led to reduction in serious CV events (HR 0.57!)…
Nov 10, 2025 · 15 shares · 617 followersView post →
SM
Sofia Valentina Marchetti
@SofiaValen726 · X
RT @pnatarajanmd: PISCES: Among 1228 pts on HD, 4g omega-3 fatty acids vs corn oil placebo led to reduction in serious CV events (HR 0.57!)…
Nov 10, 2025 · 15 shares · 320 followersView post →
MP
Mario Jimenez MD. PhD
@DrMarioJimenez1 · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 10, 2025 · 84 shares · 407 followersView post →
SG
Severo Maximo de Gante
@vampirofronte · X
RT @pnatarajanmd: PISCES: Among 1228 pts on HD, 4g omega-3 fatty acids vs corn oil placebo led to reduction in serious CV events (HR 0.57!)…
Nov 10, 2025 · 15 shares · 238 followersView post →
KS
Krishna Saketh
@krishnaathmak · X
RT @venkmurthy: Wow. Huge effect of fish oil on CVD outcomes for patients on hemodialysis!
‼️43% reduction in serious cardiac events
❗Sig…
RT @pnatarajanmd: PISCES: Among 1228 pts on HD, 4g omega-3 fatty acids vs corn oil placebo led to reduction in serious CV events (HR 0.57!)…
Nov 9, 2025 · 15 shares · 2,570 followersView post →
OH
ong beng hooi
@ongbenghooi1 · X
RT @venkmurthy: Wow. Huge effect of fish oil on CVD outcomes for patients on hemodialysis!
‼️43% reduction in serious cardiac events
❗Sig…
Nov 9, 2025 · 58 shares · 550 followersView post →
HH
Hiroki Hadano
@tkisogib4 · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 9, 2025 · 84 shares · 140 followersView post →
SH
Swapnil Hiremath
@hswapnil.medsky.social · Bluesky
CONFIDENCE post hoc analysis by albuminuria and GFR pubmed.ncbi.nlm.nih.gov/41196655/
PISCES pubmed.ncbi.nlm.nih.gov/41201837/
LIBERATE-D pubmed.ncbi.nlm.nih.gov/41201895/
Creatinine - Cystatin C GFR pubmed.ncbi.nlm.nih.gov/41202182/
GBD CKD www.thelancet.com/journals/lan...
#KidneyWk
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 9, 2025 · 84 shares · 733 followersView post →
PN
Pradeep Natarajan
@pnatarajanmd · X
PISCES: Among 1228 pts on HD, 4g omega-3 fatty acids vs corn oil placebo led to reduction in serious CV events (HR 0.57!). https://t.co/fJNeyKFWMk @NEJM
This is on the background of null STRENGTH (4g omega-3 carboxylic acids vs corn oil in high CV risk pts https://t.co/OMVtKa6u5D
Nov 9, 2025 · 67 likes · 15 shares · 25,717 followersView post →
LC
Luis Davalos CARDIOLOGIA
@KKATODD · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 9, 2025 · 84 shares · 700 followersView post →
き
きんちょJOY
@JOY81666948 · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 9, 2025 · 84 shares · 468 followersView post →
CP
Carlos Palacio
@CAPE1223 · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 9, 2025 · 84 shares · 1,024 followersView post →
DM
Dr. Praveen Shivchandra Mohadeb
@captainmohadeb · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 9, 2025 · 84 shares · 655 followersView post →
MF
Mónica Furlano
@m_furlano · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 9, 2025 · 84 shares · 968 followersView post →
FG
Felice Gragnano
@FeliceGragnano · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 9, 2025 · 84 shares · 5,398 followersView post →
DE
Diana Rodríguez Espinosa
@dianarodespi · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 9, 2025 · 84 shares · 1,061 followersView post →
GS
Global Reg Services
@Global_Reg_Svcs · X
RT @WeitzSportChiro: Fish Oil supplementation significantly reduced serious cardiovascular events in patients undergoing dialysis https://t…
Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis. #AHA25 https://t.co/v9eZv3xKoE
Nov 8, 2025 · 23 likes · 3 shares · 31,413 followersView post →
FA
Fadel Alrowaie
@fadelrowaie · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 8, 2025 · 84 shares · 25,291 followersView post →
CJ
Charles JC
@charlesjc41193 · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 8, 2025 · 84 shares · 418 followersView post →
CT
Cristina Tejera
@cristinatejerap · X
Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis | New England Journal of Medicine https://t.co/5xt3QPjUyw @NEJM #aha2025
Nov 8, 2025 · 5 likes · 1 share · 11,588 followersView post →
JM
Johann Morelle
@JohannMorelle · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 8, 2025 · 84 shares · 675 followersView post →
HH
Herbs and Havoc
@HerbsAndHavoc · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 8, 2025 · 84 shares · 363 followersView post →
FM
Francisca Martínez
@famartinez2001 · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 8, 2025 · 84 shares · 10,020 followersView post →
CM
Carlos Moreno
@cgmorenot · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 8, 2025 · 84 shares · 431 followersView post →
H
Hernan
@HtajesHernan · X
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
RT @NEJM: Original Article: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (PISCES trial) https://t.…
Nov 8, 2025 · 84 shares · 3,046 followersView post →
BM
BaladoCritique : club de lecture médical
@baladocritique.bsky.social · Bluesky
“Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis.”
Publié dans le @nejm.org.
#MedSky #NephSky
www.nejm.org/doi/full/10....
Excellent study with positive results, let's hope another study confirms this.
Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis | New England Journal of Medicine
In the PISCES trial involving participants receiving hemodialysis, fish oil (n−3 fatty acids) was compared with corn-oil placebo. The rate of serious cardiovascular events was lower with daily fish-oil supplementation. Full trial results: nej.md/49zWuqo
@asnkidney.bsky.social | #KidneyWk
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doi: 10.1056/NEJMoa2513032. PubMed. Lok CE , ; PISCES Investigators . Fish-oil supplementation and cardiovascular events in patients receiving hemodialysis ...
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DOI: 10.1056/NEJMoa2513032. This trial protocol has been provided by the authors to give readers additional information about the work. Download fulltext IDR ...
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