PubHawk
Science December 1974 PMID 4432067

Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism.

J Imperato-McGinley, L Guerrero, T Gautier, R E Peterson

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Mentions

43
Peak: 2 in Dec 2023
across 5 sources since Jun 2020

Extended reach

519,301
potential audience

Total likes

9,451

Video views

482,057

Mentions per month

Jun 2020 – Nov 2025

Where it's discussed

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AI synopsis

What people are saying

Overall, discussions reflect curiosity about the biological aspects of the condition and its social implications, with examples like mentions of gender identity and external genitalia, indicating that the publication sparks conversations about both science and societal norms. The tone ranges from serious scientific acknowledgment to peripheral social commentary, influencing its perceived moderate impact and engagement levels.

AgreementNeither agree nor disagree

The discussions show mixed reactions; some acknowledge the scientific findings, while others question or dismiss aspects of the articles or related social issues.

InterestModerate interest

Based on the variety of comments, there is a modest interest, especially from users referencing the study and its implications, but some comments diverge into unrelated topics.

EngagementModerate engagement

Many users reference the publication directly, discussing its findings and related gender identity topics, indicating a moderate level of engagement.

ImpactModerate impact

The comments touch on social implications and biological understanding, suggesting the publication has some influence on conversations about gender and medical genetics.

Abstract in brief

  • Steroid 5-alpha-reductase deficiency is a genetic disorder that causes male pseudohermaphroditism, leading to ambiguous external genitalia at birth.
  • During puberty, affected individuals show increased virilization, but biochemical tests reveal very low levels of dihydrotestosterone due to reduced enzyme activity.
  • The condition is inherited in an autosomal recessive pattern and affects fetal development by impairing the masculinization of external genitalia.]
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Top posts

Most liked on X and Bluesky
Ivette
@cattivasdq · X

@teamogatitoque Años estudiando fenómenos atípicos en pequeñas comunidades: https://t.co/MSutGbgd33

Feb 4, 2025 · 5 likes · 142 followers View post →
Alessandra Asteriti
@AlessandraAster · X

@Zoe_Brain @GehegeDrei They were male children with this condition https://t.co/4xc6P03xP3

Dec 5, 2023 · 18,045 followers View post →
GeniusDXck
@XisDifferent · X

Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism https://t.co/r9jpNWyi8B

Jul 24, 2023 · 13,394 followers View post →
Julia
@giufuliafa · X

@shawntheverbose @chinwagger102 @Prof_Wombat @summerbrennan This was the main study that also discussed gender identity https://t.co/OoCNqKPdzR

Jun 7, 2020 · 2,972 followers View post →
James V. Kohl
@microRNApro · X

https://t.co/q5oqnwdLne “...boxers who were born as woman [sic]...raised as woman, who have passports as a woman... This is legally the definition of a woman.” See for comparison: https://t.co/yeoWeMYeTM (1974) "penis at 12" (external genitalia with marked virilization at

Aug 3, 2024 · 2,569 followers View post →
El Drakan
@eldrakan · X

@DigDoug5 @itsletlearn @englishlearntip Julianne Imperato-McGinley, Luis Guerrero, Teofilo Gautier et Ralph Edward Peterson, « Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism », Science, vol. 186, no 4170, décembre 1974, p. 1213–1215

Feb 17, 2025 · 125 followers View post →

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Steroid 5-alpha-reductase deficiency is a genetic disorder causing male pseudohermaphroditism, leading to ambiguous genitalia at birth. During puberty, virilization occurs but with low dihydrotestosterone levels…

Haircafe · Jun 19, 2023 23,901 views
El Drakan
@eldrakan · X

@DigDoug5 @itsletlearn @englishlearntip Julianne Imperato-McGinley, Luis Guerrero, Teofilo Gautier et Ralph Edward Peterson, « Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism », Science, vol. 186, no 4170, décembre 1974, p. 1213–1215

Feb 17, 2025 · 125 followers View post →
Ivette
@cattivasdq · X

@teamogatitoque Años estudiando fenómenos atípicos en pequeñas comunidades: https://t.co/MSutGbgd33

Feb 4, 2025 · 5 likes · 142 followers View post →
James V. Kohl
@microRNApro · X

https://t.co/q5oqnwdLne “...boxers who were born as woman [sic]...raised as woman, who have passports as a woman... This is legally the definition of a woman.” See for comparison: https://t.co/yeoWeMYeTM (1974) "penis at 12" (external genitalia with marked virilization at

Aug 3, 2024 · 2,569 followers View post →
Alessandra Asteriti
@AlessandraAster · X

@Zoe_Brain @GehegeDrei They were male children with this condition https://t.co/4xc6P03xP3

Dec 5, 2023 · 18,045 followers View post →
GeniusDXck
@XisDifferent · X

Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism https://t.co/r9jpNWyi8B

Jul 24, 2023 · 13,394 followers View post →
Julia
@giufuliafa · X

@shawntheverbose @chinwagger102 @Prof_Wombat @summerbrennan This was the main study that also discussed gender identity https://t.co/OoCNqKPdzR

Jun 7, 2020 · 2,972 followers View post →