PubHawk
Int J Dermatol June 1995 PMID 7657446

Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris.

A R Shalita, J G Smith, L C Parish, M S Sofman, D K Chalker

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Mentions

21
Peak: 3 in Nov 2020
across 5 sources since Nov 2020

Extended reach

191,906
potential audience

Total likes

3,996

Video views

118,220

Mentions per month

Nov 2020 – Apr 2024

Where it's discussed

  • Facebook6 posts
  • X / Twitter5 posts
  • News5 articles
  • YouTube3 videos
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reflect balanced views, with posts like 'nicotinamide offers a promising nonantimicrobial alternative' highlighting interest in new treatments, while mentions of its comparable efficacy demonstrate engagement and recognition of its potential impact on acne management practices.

AgreementModerate agreement

Most discussions recognize the comparable efficacy of nicotinamide and clindamycin, reflecting general agreement with the findings.

InterestModerate interest

Posts show moderate interest, with some expressing curiosity about alternatives to antibiotics for acne treatment.

EngagementModerate engagement

Participants reference the article's results and mechanisms, showing a reasonable level of engagement.

ImpactModerate impact

Discussions emphasize the potential shift towards non-antimicrobial options, suggesting some awareness of clinical significance.

Abstract in brief

  • The study compares the safety and effectiveness of 4% nicotinamide gel to 1% clindamycin gel in treating moderate inflammatory acne vulgaris over 8 weeks, finding that both treatments show similar improvements.
  • Both treatments significantly reduced acne lesions and severity, with 82% of patients using nicotinamide and 68% using clindamycin showing improvement, indicating comparable efficacy.
  • Since clindamycin, being an antimicrobial, can lead to resistant bacteria, nicotinamide gel offers a promising nonantimicrobial alternative for managing acne without the risk of microbial resistance.
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Top posts

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ぽん
@yasu0804 · X

肌のシワ、色素沈着、黄色味を減少（美白）させ、弾力を向上させるナイアシンアミド。 実はニキビにも効く。ニキビ治療薬の抗生物質と同程度の効果ありとの報告。 中等症のニキビに対して、ニコチンアミドはクリンダマイシンと同等の有効性であった。76名のRCT https://t.co/ZhrYNG5UEH

Dec 14, 2020 · 16 likes · 2 shares · 4,608 followers View post →
เมียหมอขอรีวิว
@thedocterswife · X

Shalita, Alan R., et al. "Topical nicotinamide compared with clindamycin gel in the treatment of inelammatory acne vulgaris." International journal of dermatology 34.6 (1995) Skin Pharmacol Physiol 2014, Niacinamide - Mechanisms of Action and Its Topical Use in Dermatology

Nov 28, 2020 · 4 likes · 2 shares · 57,022 followers View post →
แม่ซอลมาแล้ว แตกแตน non - stop
@Sone_titaree · X

RT @thedocterswife: Shalita, Alan R., et al. "Topical nicotinamide compared with clindamycin gel in the treatment of inelammatory acne vulg…

Nov 28, 2020 · 2 shares · 8,892 followers View post →
fufu |
@rundinganfoe · X

Sumber: https://t.co/bbsyBCAGVq https://t.co/bgwmKqAeD6 https://t.co/COF2wGc23j https://t.co/adgJCPrSTl https://t.co/wAAhn59zBf https://t.co/zl45vhzR2G https://t.co/zN0wlzZSFE https://t.co/Qlv719sUBk

Oct 25, 2021 · 2,903 followers View post →

All mentions

fufu |
@rundinganfoe · X

Sumber: https://t.co/bbsyBCAGVq https://t.co/bgwmKqAeD6 https://t.co/COF2wGc23j https://t.co/adgJCPrSTl https://t.co/wAAhn59zBf https://t.co/zl45vhzR2G https://t.co/zN0wlzZSFE https://t.co/Qlv719sUBk

Oct 25, 2021 · 2,903 followers View post →
ぽん
@yasu0804 · X

肌のシワ、色素沈着、黄色味を減少（美白）させ、弾力を向上させるナイアシンアミド。 実はニキビにも効く。ニキビ治療薬の抗生物質と同程度の効果ありとの報告。 中等症のニキビに対して、ニコチンアミドはクリンダマイシンと同等の有効性であった。76名のRCT https://t.co/ZhrYNG5UEH

Dec 14, 2020 · 16 likes · 2 shares · 4,608 followers View post →
แม่ซอลมาแล้ว แตกแตน non - stop
@Sone_titaree · X

RT @thedocterswife: Shalita, Alan R., et al. "Topical nicotinamide compared with clindamycin gel in the treatment of inelammatory acne vulg…

Nov 28, 2020 · 2 shares · 8,892 followers View post →
...
@todayitistoday · X

RT @thedocterswife: Shalita, Alan R., et al. "Topical nicotinamide compared with clindamycin gel in the treatment of inelammatory acne vulg…

Nov 28, 2020 · 2 shares · 246 followers View post →
เมียหมอขอรีวิว
@thedocterswife · X

Shalita, Alan R., et al. "Topical nicotinamide compared with clindamycin gel in the treatment of inelammatory acne vulgaris." International journal of dermatology 34.6 (1995) Skin Pharmacol Physiol 2014, Niacinamide - Mechanisms of Action and Its Topical Use in Dermatology

Nov 28, 2020 · 4 likes · 2 shares · 57,022 followers View post →