Am J Physiol May 1994 PMID 8203511

Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis.

P L Greenhaff, K Bodin, K Soderlund, E Hultman

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What people are saying

Discussion discussions reveal a generally positive view on creatine's role in muscle recovery, highlighted by comments about its potential benefits and variability in effects. The tone varies from casual remarks like 'Hot tea or coffee is fine' to more specific observations about individual responses, reflecting both curiosity and skepticism about the results' broad applicability.

AgreementModerate agreement

Most discussions recognize the value of creatine supplementation, with some showing strong support, though not all fully agree on its universal benefits.

InterestHigh interest

Posts display high interest in understanding supplement effects and practical implications, especially referencing individual variability in responses.

EngagementModerate engagement

Several posts delve into personal experiences or broader implications, indicating moderate thoughtful engagement beyond surface-level reactions.

ImpactNeutral impact

While some consider the study’s implications potentially influential for dietary and athletic practices, the overall perceived impact remains moderate.

Abstract in brief

The study investigated how oral creatine supplements affect the recovery of phosphocreatine (PCr) in skeletal muscle after intense contraction, showing that in most subjects, creatine intake increased muscle total creatine levels and improved PCr resynthesis during recovery.
Ten days after an initial test, the procedure was repeated with the other leg, where subjects had ingested 20 grams of creatine per day for 5 days, revealing variability in response: some showed significant increases in muscle creatine and PCr resynthesis, while others showed minimal change.
The findings suggest that increasing muscle total creatine through diet can enhance the muscle's ability to resynthesize PCr during the early phase (second minute) of recovery after intense exercise, but individual responses vary.]

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