The overall sentiment underscores the importance of the 1993 article in the history of molecular biology, with phrases like 'started a revolution' and references to CRISPR, showing respect and recognition for the research's foundational role. The tone and wording emphasize both the scientific achievement and its transformative impact, which drives the moderate to high scores on interest and agreement.
AgreementModerate agreement
Most discussions acknowledge the importance of the 1993 study, especially its role in the development of CRISPR technology, reflecting general agreement with its scientific significance.
InterestHigh interest
Posts show high interest due to references to revolutionary impacts in genetic research and mentions of foundational research articles from 1993, highlighting curiosity about the scientific process.
EngagementModerate engagement
Several comments delve into the implications of the research, including mentions of molecular mechanisms and historical context, indicating moderate levels of critical engagement.
ImpactModerate impact
Discussions suggest that the study marked a significant step towards groundbreaking tools like CRISPR, indicating a recognition of its field-wide influence.
Abstract in brief
The study investigated genomic sequences of *Haloferax mediterranei* near PstI restriction sites that showed modifications depending on the salt concentration in the growth medium.
Two open reading frames (genes) were identified that are differentially expressed based on salinity, with PstI sites located in noncoding regions containing repetitive motifs and Z-DNA-like structures.
The findings suggest that changes in local DNA structure, possibly influenced by salt levels, could play a role in osmoregulation for this halophilic archaeon.]
@turco_otomano Empieza por conocer el stack tecnológico actual básico. El que hay hoy:
https://t.co/iZNhlG6kW9
Dec 13, 2021 · 3 likes · 1 share · 5,105 followersView post →
RC
Rafael Camarillo
@RafaCamarilloIQ · X
Con este artículo de Mojica en 1993 empezó una de las grandes revoluciones de la ciencia del siglo XXI #Ahombrosdegigantes #CRISPR
Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially modified PstI sites https://t.co/kszuB0K89p
Oct 7, 2020 · 2 likes · 3 shares · 2,020 followersView post →
SB
Stuart Buck
@stuartbuck1 · X
@Dominic2306 @Ben_Reinhardt Doesn't seem to work well for truly basic research. This 1993 article eventually led to CRISPR, but no one in 1993 would have been able to answer the Heilmeier questions: https://t.co/684UkuBW7N
Oct 26, 2021 · 1 like · 6,912 followersView post →
MM
Medicina Hongos Comestibles. Medicinal Mushrooms.
@flodalila01 · X
@Biotechfelipe @JohnGalt_is_www Luego en 1993 Mojica y otros publicaron el siguiente articulo que en base a Ishino se identifica los rearreglos CRISPR en arqueas- DOI: 10.1111/j.1365-2958.1993.tb01721.x
CRISPR-Cas systems are powerful tools for precise genome editing, utilizing RNA guides to direct Cas9 to specific DNA sequences in human and mouse cells. Recent advances allow for single-strand cuts and the simultaneous…
Discover the revolutionary power of CRISPR-Cas9 gene editing technology, which is transforming science and medicine by enabling disease resistance, bacterial plastic digestion, and potential cures for genetic disorders.
RT @TheDevilOps: @turco_otomano Empieza por conocer el stack tecnológico actual básico. El que hay hoy:
https://t.co/iZNhlG6kW9
Dec 14, 2021 · 1 share · 1,581 followersView post →
AS
Abel Losada Esperante #IWantToBelieve #SkynetCult
@TheDevilOps · X
@turco_otomano Empieza por conocer el stack tecnológico actual básico. El que hay hoy:
https://t.co/iZNhlG6kW9
Dec 13, 2021 · 3 likes · 1 share · 5,105 followersView post →
SB
Stuart Buck
@stuartbuck1 · X
@Dominic2306 @Ben_Reinhardt Doesn't seem to work well for truly basic research. This 1993 article eventually led to CRISPR, but no one in 1993 would have been able to answer the Heilmeier questions: https://t.co/684UkuBW7N
Oct 26, 2021 · 1 like · 6,912 followersView post →
AN
Ammu Neuroscience
@ammuneuroscien2 · X
Mojica, F.J.; Juez, G.; Rodríguez-Valera, F. (1993). «Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially modified PstI sites». Molecular Microbiology (en inglés) 9 (3): 613—-621.
Lander, Eric S. (2016). «The Heroes of CRISPR». Cell
@Biotechfelipe @JohnGalt_is_www Luego en 1993 Mojica y otros publicaron el siguiente articulo que en base a Ishino se identifica los rearreglos CRISPR en arqueas- DOI: 10.1111/j.1365-2958.1993.tb01721.x
@DiazCTatiana @LluisMontoliu @astro_duque I ja havia publicat a 1993 un article sobre aquestes seqüències genòmiques en l'arquea halòfila 'Haloferax mediterranei'.
https://t.co/6D0l4LrSBQ
Con este artículo de Mojica en 1993 empezó una de las grandes revoluciones de la ciencia del siglo XXI #Ahombrosdegigantes #CRISPR
Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially modified PstI sites https://t.co/kszuB0K89p
Oct 7, 2020 · 2 likes · 3 shares · 2,020 followersView post →
B
Bioaprender
@Bioaprender · X
Mojica FJ, Juez G, Rodriguez-Valera F. (1993). Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially modified PstI sites. Mol Microbiol 9:613–21.
The Plant Genome - 2025 - Namata - Genome Editing in Maize and ...
News
https://doi.org/10.1111/j.1365-2958.1993.tb01721.x nucleases. Nature Biotechnology, 23(8), 967–973. https://doi.org/10. Mushtaq, M., Bhat, J. A., Mir, Z. A. ...