Capgras syndrome: a novel probe for understanding the neural representation of the identity and familiarity of persons.

Abstract in brief

• Capgras syndrome involves patients believing that familiar people, like family members, are imposters, and this case study explores a patient with unique features such as modality-specific delusions and abnormal responses to familiar faces.
• The patient's inability to distinguish from familiar and unfamiliar faces based on skin conductance responses and difficulty judging gaze direction suggests damage in the neural connections between face-processing areas and the limbic system, which impacts recognition and emotional response.
• These findings imply that Capgras syndrome can provide insights into how the brain forms and links memories of individuals, highlighting the neural mechanisms behind identity, familiarity, and memory formation.]