N Engl J Med November 1997 PMID 9366579

A case-control study of HIV seroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group.

D M Cardo, D H Culver, C A Ciesielski, P U Srivastava, R Marcus, D Abiteboul, J Heptonstall, G Ippolito, F Lot, P S McKibben, D M Bell

Mentions

20
Peak: 3 in Aug 2020
across 4 sources since Dec 2017

Extended reach

208,017
potential audience

Total likes

369

Video views

87,462

Mentions per month

Dec 2017 – Nov 2025

Where it's discussed

  • X / Twitter10 posts
  • News5 articles
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The overall sentiment reflects curiosity and recognition of the importance of post-exposure prophylaxis, with some discussions promoting educational resources like animated videos and contact numbers, while others include promotional tones. The tone and varied content suggest a balanced interest in HIV prevention, with some posts emphasizing the practical impact of the study's findings on healthcare safety protocols.

AgreementNeither agree nor disagree

The discussions show mixed reactions; some posts support the importance of prophylaxis like PEP, but others are more casual or promotional, indicating no strong consensus.

InterestModerate interest

There is a moderate level of interest, with many posts asking questions about PEP or sharing related information, but some seem to focus on advertisements rather than scientific details.

EngagementModerate engagement

Several discussions reference educational content, such as animated videos and contact info, suggesting a fair level of engagement; however, some posts are short or promotional, indicating shallow involvement.

ImpactModerate impact

The posts highlight the relevance of HIV prevention measures and PEP, implying they recognize the significance of the study’s implications for healthcare practices, but not all posts directly address the core findings.

Abstract in brief

  • This study examined the factors influencing the risk of HIV transmission to healthcare workers after needlestick injuries, finding that deeper injuries, visibly contaminated devices, procedures involving arteries or veins, and exposure to patients who recently died of AIDS significantly increased the risk of seroconversion.
  • The research also revealed that healthcare workers who took zidovudine after exposure were much less likely to become HIV positive, suggesting that postexposure prophylaxis is effective in reducing infection risk.
  • Overall, the risk of HIV infection is higher with larger blood volumes and possibly higher HIV concentrations in the source patient’s blood, emphasizing the importance of safety measures and timely prophylactic treatment.

Top posts

Most liked on X and Bluesky
Harry Poppers™️
@harrypoppersph · X

want to know about PEP? https://t.co/LDdoHB9Yq3 https://t.co/3FrgkxHvO8

Aug 20, 2020 · 5 likes · 2 shares · 45,359 followers View post →
IntegralAnswers
@IntegralAnswers · X

@thereal_truther A case-control study of HIV seroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group https://t.co/4L7NDBDj3y

Feb 6, 2024 · 3 likes · 8,591 followers View post →
Harry Poppers™️
@harrypoppersph · X

lets PEP talk. get this for 10% off. want to know more about PEP? click is the key https://t.co/LDdoHASn1t https://t.co/rxcNMnhwyY

Oct 4, 2020 · 2 likes · 45,359 followers View post →
Dr. Michael DACM
@internetuserf12 · X

@jeanerus HIV(needlestick): https://t.co/fz93jgsp9A HIV(perinatal): https://t.co/3eKJdT7jmc HepC(transfusion): https://t.co/lol9UQ2RRM Ebola(sexual): https://t.co/6e0HZgLZZC Norovirus(vomitus): https://t.co/4QVSpgf0Xg

Nov 12, 2025 · 7,662 followers View post →
Jeric Perez
@jericperez_ph · X

RT @harrypoppers18: want to know about PEP? https://t.co/LDdoHB9Yq3 https://t.co/3FrgkxHvO8

Aug 20, 2020 · 2 shares · 6,421 followers View post →
IDEA AMELIORATOR;INNOVATOR; #InPlainSight INVENTOR
@Amethyst7purple · X

#Kenyans #Ukimwi https://t.co/4LPjfDBM1j

Sep 17, 2019 · 3,211 followers View post →

All mentions

Dr. Michael DACM
@internetuserf12 · X

@jeanerus HIV(needlestick): https://t.co/fz93jgsp9A HIV(perinatal): https://t.co/3eKJdT7jmc HepC(transfusion): https://t.co/lol9UQ2RRM Ebola(sexual): https://t.co/6e0HZgLZZC Norovirus(vomitus): https://t.co/4QVSpgf0Xg

Nov 12, 2025 · 7,662 followers View post →
IntegralAnswers
@IntegralAnswers · X

@thereal_truther A case-control study of HIV seroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group https://t.co/4L7NDBDj3y

Feb 6, 2024 · 3 likes · 8,591 followers View post →
Proactive Community Services
@LetsBeProactive · X

Let's Give a PEP Talk! An Antiretroviral Therapy for HIV Prevention https://t.co/Yj7M5Qnhk5

Oct 8, 2020 · 32 followers View post →
Harry Poppers™️
@harrypoppersph · X

lets PEP talk. get this for 10% off. want to know more about PEP? click is the key https://t.co/LDdoHASn1t https://t.co/rxcNMnhwyY

Oct 4, 2020 · 2 likes · 45,359 followers View post →
top trans
@Reddeer026 · X

RT @harrypoppers18: want to know about PEP? https://t.co/LDdoHB9Yq3 https://t.co/3FrgkxHvO8

Aug 20, 2020 · 2 shares · 108 followers View post →
Jeric Perez
@jericperez_ph · X

RT @harrypoppers18: want to know about PEP? https://t.co/LDdoHB9Yq3 https://t.co/3FrgkxHvO8

Aug 20, 2020 · 2 shares · 6,421 followers View post →
Harry Poppers™️
@harrypoppersph · X

want to know about PEP? https://t.co/LDdoHB9Yq3 https://t.co/3FrgkxHvO8

Aug 20, 2020 · 5 likes · 2 shares · 45,359 followers View post →
AIDS Free Pittsburgh
@AIDSfreePgh · X

Want to learn more about #PEP for #HIV #prevention after a potential exposure? Check out this short, animated YouTube video! https://t.co/xVNinORcfk FMI about accessing PEP in #Pittsburgh, call/text 412-773-1120 or visit https://t.co/M1Aq0QS1hl https://t.co/DP3jEPpyqp

Nov 27, 2019 · 589 followers View post →
IDEA AMELIORATOR;INNOVATOR; #InPlainSight INVENTOR
@Amethyst7purple · X

#Kenyans #Ukimwi https://t.co/4LPjfDBM1j

Sep 17, 2019 · 3,211 followers View post →
IDEA AMELIORATOR;INNOVATOR; #InPlainSight INVENTOR
@Amethyst7purple · X

#Kenya #Kenyans #AntiretroviralTherapy #PEP HIV/AIDS https://t.co/4LPjfDBM1j

May 29, 2019 · 3,211 followers View post →