49,940 results match your criteria: "Immune Checkpoint Proteins"

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T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint proteins.
Stephanie Schlichtner, Inna M Yasinska, Gurprit S Lall, Steffen M Berger, Sabrina Ruggiero

J Immunother Cancer· January 2023

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Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions.
Marius Schwabenland, Henrike Salié, Jovan Tanevski, Saskia Killmer, Marilyn Salvat Lago

Immunity· July 2021

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Clinical and molecular characterization of in colorectal cancer, CALGB (Alliance)/SWOG 80405 and real-world data.
Karam Ashouri, Joshua Millstein, Yan Yang, Joanne Xiu, Shivani Soni

J Immunother Cancer· December 2025

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A phase 1b/2 study of first-line anti-PD-L1/ TGF-βRII fusion protein SHR-1701 combined with nab-paclitaxel and gemcitabine for advanced pancreatic ductal adenocarcinoma.
Ran Xue, Miaoyan Wei, Jiajia Yuan, Zhihua Li, Yuhong Zhou

Signal Transduct Target Ther· December 2025

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Interferon therapy-induced reduction in PD-1 + CD8 + and CD160 + CD8 + T cells is associated with functional cure in hepatitis B.
Daqiong Zhou, Jiangyu Liu, Jianru Jia, Hong Li, Ling Qin

BMC Infect Dis· December 2025

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Intraperitoneal immune microenvironment and efficacy of intraperitoneal chemotherapy in patients with gastric cancer and peritoneal metastasis.
Tomoya Nakanishi, Motohiro Imano, Masashi Kohda, Hiroaki Kato, Naoko Kounami

Sci Rep· December 2025

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VNUT-mediated ATP release suppresses T helper 1 (T1) cell differentiation via the P2X7R-JNK-FOXO3a-Eomes signaling cascade.
Bolong Wu, Linlin Sheng, Ziyi Feng, Xiaohu Wang, Ligong Chen

Sci Adv· December 2025

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Radiation therapy causes a STING and MyD88-independent upregulation of CD80 and CD86 in macrophages and monocytes that limits tumor control.
Aanchal Preet Kaur, Jason R Baird, Alejandro F Alice, Gwen Kramer, David Friedman

Cancer Immunol Immunother· December 2025

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The ATR inhibitor tuvusertib (M1774) sensitizes prostate carcinoma to natural killer cell-mediated cytotoxicity, which is further augmented by the IL-15 receptor superagonist N-803.
Cailyn A Lee, Jeffrey Schlom, James W Hodge, Kellsye P Fabian

Cancer Immunol Immunother· December 2025

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Efficacy and safety of hepatic arterial infusion chemotherapy plus lenvatinib and PD-1/PD-L1 inhibitors versus systemic chemotherapy plus lenvatinib and PD-1/PD-L1 inhibitors in advanced unresectable cholangiocarcinoma: a retrospective cohort study.
Zhenzhen Zhang, Meixia Wang, Guobin Chen, Yanfang Wu, Xiaochun Chen

Cancer Immunol Immunother· December 2025

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A selective IDO1 inhibitor, KHK2455, improves efficacy of PD-L1 blockade by modulating both innate and adaptive immunity in a mouse melanoma model.
Masato Saito, Kana Kunieda, Toshihiko Ishii, Shoko Koshiba, Rui Ohashi

Cancer Immunol Immunother· December 2025

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Exploration of the benefits and resistance mechanisms of immunotherapy based on PD-L1 expression, circulating tumor DNA and T-cell receptor profiles in advanced gastric cancer.
Miaomiao Gou, Niansong Qian, Yong Zhang, Bingfa Yan, Zhikuan Wang

Cancer Immunol Immunother· December 2025

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Beyond FoxP3-Identification of a Chicken Regulatory T Cell Signature.
Isabell Naumann, Edward S Ricemeyer, Daniel Elleder, Jiri Plachy, Dominik von La Roche

Eur J Immunol· December 2025

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Advancements of investigational agents for renal cell carcinoma: what clinical progress have we seen in the last 5 years?
Linda Danielli, Matteo Rosellini, Elisa Tassinari, Andrea Marchetti, Veronica Mollica

Expert Opin Investig Drugs· December 2025

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Hypoxia induced VEGF secretion promotes resistance to bispecific T-cell engagers.
Mengyao Xu, Syem K Barakzai, Raj Kumar, Irva Veillard, Eugene Kim

Signal Transduct Target Ther· December 2025

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Inhibition of STING-mediated antiviral innate immunity activation by CD97 via modulation of ER-phagy.
Huasong Chang, Rukun Yang, Wenjing Qi, Peili Hou, Aibiao Xiang

Commun Biol· December 2025

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Gatekeepers of immunity: mechanisms and regulation of immune checkpoints and their role in immune-privileged sites.
Reza Nejad Shahrokh Abadi, Zahra Shahrokh Nejad Abadi, Sara Hooshmand

Mol Biol Rep· December 2025

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Combined CD25-targeted near infrared photoimmunotherapy (NIR-PIT) and intratumor IL-15 enhance the effectiveness of anti-PD-1 immunotherapy.
Makoto Kano, Aki Furusawa, Hiroshi Fukushima, Seiichiro Takao, Shuhei Okuyama

Cancer Immunol Immunother· December 2025

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Case Report: Pseudoprogression of pancreatic acinar cell carcinoma after PD-1 blockade integrated treatment.
Xinyuan Bai, Di Yang, Jingjing Chen, Yaru Liu, Haochen Tang

Front Immunol· December 2025

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Gemcitabine-cisplatin chemotherapy plus anti-PD-L1 therapy reinvigorates antitumor immune response by reprogramming the intrahepatic cholangiocarcinoma microenvironment.
Yang Song, Shao-Wei Huang, Bo Shu, Ying-Xia Zhou, Wei-Dong Dai

Front Immunol· December 2025

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Epigenetic activation of CD274/PD-L1 by the MSL complex expands its role beyond dosage compensation.
Aiping Wen, Xuanfei Feng, Yingying Li, Xueli Cui, Qixian Zou

Front Immunol· December 2025

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The Second Mitochondria-Derived Activator of Caspases Mimetic BI 891065 in Patients With Advanced Solid Tumors: Results From Two Phase I Studies.
Manish R Patel, Erika P Hamilton, Ben George, Gunther Kretschmar, Akiko Harada

Cancer Med· December 2025

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Toll like receptor agonist effects on human CD8+ T cell activation and expression of T cell checkpoint receptors.
Donghwan Jeon, Jena E Moseman, Ethan Hill, Douglas G McNeel

Hum Vaccin Immunother· December 2025

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Dual checkpoint inhibitor therapy versus dual targeted therapy of untreated metastatic BRAF-mutant melanoma: a systematic review of randomised controlled trials.
Frank Peinemann, Sarah Baradaran, Kevin Bernhard Arnolds, Marc Hoemberg

BMJ Open· December 2025

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Final results of ANICCA-Class II, a single arm, open-label phase II trial assessing nivolumab in tissue-specific class II expressing metastatic microsatellite stable colorectal cancer, with a parallel assessment of the immunoscore-immune checkpoint as a predictive biomarker for single-agent anti-PD-1.
Gary Middleton, Charlotte Gaskell, Joshua Savage, John Bridgewater, Paul Ross

J Immunother Cancer· December 2025

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Targeting CTGF overcomes resistance to CSF1R inhibitors by preventing CAF activation in colorectal cancer.
Bojun Wang, Yingjue Li, Mengde Shi, Yuanyu Liao, Yuli Ruan

Cell Rep Med· December 2025

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CfDNA-based copy-number dynamics during anti-PD1 treatment in metastatic triple negative breast cancer.
Aaron Y Lin, Olga I Isaeva, Teoman Deger, Veerle C M Geurts, Daan C L Vessies

Cell Rep Med· December 2025

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Combining Radiation and anti-PD-L1 Enhances the Antitumor Activity in Colorectal Cancer via IFN-γ-Dependent Activation of STAT1.
Xiao Yang, Dan-Dan Gao, Heng Zhang, Wan-Jun Sun, Si-Wei Zhu

Technol Cancer Res Treat· December 2025

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Decoding mA readers: roles of YTHDF proteins in leukemogenesis and cancer immunity.
Chunhong Li, Xi Chen, Shanrui Pu, Kun Lian, Lihua Li

Front Immunol· December 2025

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