Publications by authors named "A A Denholm"

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Discovery and Optimization of 4-(8-(3-Fluorophenyl)-1,7-naphthyridin-6-yl)transcyclohexanecarboxylic Acid, an Improved PDE4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease (COPD).
Neil J Press, Roger J Taylor, Joseph D Fullerton, Pamela Tranter, Clive McCarthy, Alastair Denholm

J Med Chem· September 2015

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Solubility-driven optimization of phosphodiesterase-4 inhibitors leading to a clinical candidate.
Neil J Press, Roger J Taylor, Joseph D Fullerton, Pamela Tranter, Clive McCarthy, Alastair Denholm

J Med Chem· September 2012

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Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists.
Andrew G Cole, Axel Metzger, Marc-Raleigh Brescia, Lan-Ying Qin, Kenneth C Appell, Alastair A Denholm

Bioorg Med Chem Lett· January 2009

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The synthesis of azadirachtin: a potent insect antifeedant.
Steven V Ley, Antonio Abad-Somovilla, James C Anderson, Carles Ayats, Rolf Bänteli, Alastair A Denholm

Chemistry· December 2008

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Differential identification of a rare form of platelet-type (pseudo-) von Willebrand disease (VWD) from Type 2B VWD using a simplified ristocetin-induced-platelet-agglutination mixing assay and confirmed by genetic analysis.
Emmanuel J Favaloro, David Patterson, Anna Denholm, Scott Mead, Ann Gilbert

Br J Haematol· November 2007

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