Publications by authors named "Aaron A Witham"

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Enhancing Bulge Stabilization through Linear Extension of C8-Aryl-Guanine Adducts to Promote Polymerase Blockage or Strand Realignment to Produce a C:C Mismatch.
Michael Sproviero, Anne M R Verwey, Aaron A Witham, Richard A Manderville, Purshotam Sharma

Chem Res Toxicol· August 2015

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Chlorine functionalization of a model phenolic C8-guanine adduct increases conformational rigidity and blocks extension by a Y-family DNA polymerase.
Aaron A Witham, Anne M R Verwey, Michael Sproviero, Richard A Manderville, Purshotam Sharma

Chem Res Toxicol· June 2015

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Positional impact of fluorescently modified G-tetrads within polymorphic human telomeric G-quadruplex structures.
Michael Sproviero, Kaila L Fadock, Aaron A Witham, Richard A Manderville

ACS Chem Biol· May 2015

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Chlorine substitution promotes phenyl radical loss from C8-phenoxy-2'-deoxyguanosine adducts: implications for biomarker identification from chlorophenol exposure.
Aaron A Witham, Purshotam Sharma, Stacey D Wetmore, Wojciech Gabryelski, Richard A Manderville

J Mass Spectrom· January 2015

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Structural and biochemical impact of C8-aryl-guanine adducts within the NarI recognition DNA sequence: influence of aryl ring size on targeted and semi-targeted mutagenicity.
Michael Sproviero, Anne M R Verwey, Katherine M Rankin, Aaron A Witham, Dmitriy V Soldatov

Nucleic Acids Res· December 2014

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Utility of 5'-O-2,7-dimethylpixyl for solid-phase synthesis of oligonucleotides containing acid-sensitive 8-aryl-guanine adducts.
Michael Sproviero, Katherine M Rankin, Aaron A Witham, Richard A Manderville

J Org Chem· January 2014

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Structural influence of C8-phenoxy-guanine in the NarI recognition DNA sequence.
Michael S Kuska, Aaron A Witham, Michael Sproviero, Richard A Manderville, Mohadeseh Majdi Yazdi

Chem Res Toxicol· September 2013

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Influence of chlorine substitution on the hydrolytic stability of biaryl ether nucleoside adducts produced by phenolic toxins.
Michael S Kuska, Mohadeseh Majdi Yazdi, Aaron A Witham, Heidi A Dahlmann, Shana J Sturla

J Org Chem· July 2013

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Hydroxyl radical-induced oxidation of a phenolic C-linked 2'-deoxyguanosine adduct yields a reactive catechol.
Aaron A Witham, Daniel G Beach, Wojciech Gabryelski, Richard A Manderville

Chem Res Toxicol· February 2012

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