Publications by authors named "Aaron Aponick"

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Enantioselective Synthesis of Allylic Sulfones via Rhodium-Catalyzed Direct Hydrosulfonylation of Allenes and Alkynes.
Chieh-Yu Chang, Aaron Aponick

J Am Chem Soc· June 2024

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Chemoselective Diazine Dearomatization: The Catalytic Enantioselective Dearomatization of Pyrazine.
Devin R Ketelboeter, Mukesh Pappoppula, Aaron Aponick

J Am Chem Soc· May 2024

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Catalytic Enantioselective Alkyne Addition to Nitrones Enabled by Tunable Axially Chiral Imidazole-Based P,N-Ligands.
Shengkang Yin, Kendall N Weeks, Aaron Aponick

J Am Chem Soc· March 2024

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Catalytic Enantioselective Synthesis of Axially Chiral Imidazoles by Cation-Directed Desymmetrization.
Shengkang Yin, Ji Liu, Kendall N Weeks, Aaron Aponick

J Am Chem Soc· December 2023

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Enantio- and Regioselective Copper-Catalyzed 1,2-Dearomatization of Pyridines.
Mukesh Pappoppula, Kathryn L Olsen, Devin R Ketelboeter, Aaron Aponick

Angew Chem Int Ed Engl· November 2023

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PLA-Triggered Activation of Cyclosporine-Phospholipid Prodrug as a Drug Targeting Approach in Inflammatory Bowel Disease Therapy.
Milica Markovic, Shimon Ben-Shabat, Jagadeesh Nagendra Manda, Karina Abramov-Harpaz, Clil Regev, Aaron Aponick

Pharmaceutics· March 2022

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Prodrug-Based Targeting Approach for Inflammatory Bowel Diseases Therapy: Mechanistic Study of Phospholipid-Linker-Cyclosporine PLA-Mediated Activation.
Milica Markovic, Karina Abramov-Harpaz, Clil Regev, Shimon Ben-Shabat, Aaron Aponick

Int J Mol Sci· February 2022

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Enantioselective Lactonization by π-Acid-Catalyzed Allylic Substitution: A Complement to π-Allylmetal Chemistry.
Arun Raj Kizhakkayil Mangadan, Ji Liu, Aaron Aponick

Angew Chem Int Ed Engl· October 2021

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Configuration Sampling With Five-Membered Atropisomeric P,N-Ligands.
Gaurav Dahiya, Mukesh Pappoppula, Aaron Aponick

Angew Chem Int Ed Engl· September 2021

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Synthesis and Biological Evaluation of the Southern Hemisphere of Spirastrellolide A and Analogues.
Jagadeesh Nagendra Manda, Barry B Butler, Aaron Aponick

J Org Chem· November 2020

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Phospholipid Cyclosporine Prodrugs Targeted at Inflammatory Bowel Disease (IBD) Treatment: Design, Synthesis, and in Vitro Validation.
Jagadeesh Nagendra Manda, Milica Markovic, Ellen M Zimmermann, Shimon Ben-Shabat, Arik Dahan, Aaron Aponick

ChemMedChem· September 2020

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Lipids and Lipid-Processing Pathways in Drug Delivery and Therapeutics.
Milica Markovic, Shimon Ben-Shabat, Aaron Aponick, Ellen M Zimmermann, Arik Dahan

Int J Mol Sci· May 2020

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The prospects of lipidic prodrugs: an old approach with an emerging future.
Arik Dahan, Milica Markovic, Aaron Aponick, Ellen M Zimmermann, Shimon Ben-Shabat

Future Med Chem· October 2019

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Lactone Synthesis by Enantioselective Orthogonal Tandem Catalysis.
Sourabh Mishra, Aaron Aponick

Angew Chem Int Ed Engl· July 2019

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A Facile Enantioselective Alkynylation of Chromones.
Lindsey G DeRatt, Mukesh Pappoppula, Aaron Aponick

Angew Chem Int Ed Engl· June 2019

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Molecular Modeling-Guided Design of Phospholipid-Based Prodrugs.
Milica Markovic, Shimon Ben-Shabat, Shahar Keinan, Aaron Aponick, Ellen M Zimmermann

Int J Mol Sci· May 2019

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Phospholipid-Based Prodrugs for Colon-Targeted Drug Delivery: Experimental Study and In-Silico Simulations.
Milica Markovic, Arik Dahan, Shahar Keinan, Igor Kurnikov, Aaron Aponick

Pharmaceutics· April 2019

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Lipidic prodrug approach for improved oral drug delivery and therapy.
Milica Markovic, Shimon Ben-Shabat, Shahar Keinan, Aaron Aponick, Ellen M Zimmermann

Med Res Rev· March 2019

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Prospects and Challenges of Phospholipid-Based Prodrugs.
Milica Markovic, Shimon Ben-Shabat, Shahar Keinan, Aaron Aponick, Ellen M Zimmermann

Pharmaceutics· November 2018

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Enol Acetates: Versatile Substrates for the Enantioselective Intermolecular Tsuji Allylation.
Ji Liu, Sourabh Mishra, Aaron Aponick

J Am Chem Soc· November 2018

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Catalytic Dehydrative Lactonization of Allylic Alcohols.
Ji Liu, Romain J Miotto, Julien Segard, Ashley M Erb, Aaron Aponick

Org Lett· May 2018

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Computational modeling and in-vitro/in-silico correlation of phospholipid-based prodrugs for targeted drug delivery in inflammatory bowel disease.
Arik Dahan, Milica Markovic, Shahar Keinan, Igor Kurnikov, Aaron Aponick

J Comput Aided Mol Des· November 2017

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Phospholipid-drug conjugates as a novel oral drug targeting approach for the treatment of inflammatory bowel disease.
Arik Dahan, Milica Markovic, Svetlana Epstein, Noa Cohen, Ellen M Zimmermann, Aaron Aponick

Eur J Pharm Sci· October 2017

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Enantioselective Alkyne Conjugate Addition Enabled by Readily Tuned Atropisomeric P,N-Ligands.
Sourabh Mishra, Ji Liu, Aaron Aponick

J Am Chem Soc· March 2017

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Correction: Regioselectivity in the Au-catalyzed hydration and hydroalkoxylation of alkynes.
Justin A Goodwin, Aaron Aponick

Chem Commun (Camb)· May 2016

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