Publications by authors named "Aaron Cooper"

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High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery.
Conor J Howard, Nathan S Abell, Beatriz A Osuna, Eric M Jones, Leon Y Chan, Aaron R Cooper

Elife· April 2025

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The role of ATP citrate lyase in myelin formation and maintenance.
Andrew Schneider, Seongsik Won, Eric A Armstrong, Aaron J Cooper, Amulya Suresh

Glia· January 2025

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Modulation of Schwann cell homeostasis by the BAP1 deubiquitinase.
Phu Duong, Raghu Ramesh, Andrew Schneider, Seongsik Won, Aaron J Cooper

Glia· June 2023

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Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples.
Joshua S Bloom, Laila Sathe, Chetan Munugala, Eric M Jones, Molly Gasperini, Aaron R Cooper

Nat Biomed Eng· July 2021

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Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing.
Joshua S Bloom, Laila Sathe, Chetan Munugala, Eric M Jones, Molly Gasperini, Aaron R Cooper

medRxiv· March 2021

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Reliable and accurate diagnostics from highly multiplexed sequencing assays.
A Sina Booeshaghi, Nathan B Lubock, Aaron R Cooper, Scott W Simpkins, Joshua S Bloom

Sci Rep· December 2020

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Site-Specific Gene Editing of Human Hematopoietic Stem Cells for X-Linked Hyper-IgM Syndrome.
Caroline Y Kuo, Joseph D Long, Beatriz Campo-Fernandez, Satiro de Oliveira, Aaron R Cooper

Cell Rep· May 2018

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Characterization of Gene Alterations following Editing of the β-Globin Gene Locus in Hematopoietic Stem/Progenitor Cells.
Joseph Long, Megan D Hoban, Aaron R Cooper, Michael L Kaufman, Caroline Y Kuo

Mol Ther· February 2018

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Preclinical studies for a phase 1 clinical trial of autologous hematopoietic stem cell gene therapy for sickle cell disease.
Fabrizia Urbinati, Jennifer Wherley, Sabine Geiger, Beatriz Campo Fernandez, Michael L Kaufman, Aaron Cooper

Cytotherapy· September 2017

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Quantitative Trait Loci Mapping for Spike Characteristics in Hexaploid Wheat.
Yaopeng Zhou, Benjamin Conway, Daniela Miller, David Marshall, Aaron Cooper

Plant Genome· July 2017

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Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency.
Kit L Shaw, Elizabeth Garabedian, Suparna Mishra, Provaboti Barman, Alejandra Davila, Aaron R Cooper

J Clin Invest· May 2017

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Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients.
Aaron R Cooper, Georgia R Lill, Kit Shaw, Denise A Carbonaro-Sarracino, Alejandra Davila

Blood· May 2017

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S···O and S···N Sulfur Bonding Interactions in Protein-Ligand Complexes: Empirical Considerations and Scoring Function.
Mathew R Koebel, Aaron Cooper, Grant Schmadeke, Soyoung Jeon, Mahesh Narayan

J Chem Inf Model· December 2016

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CRISPR/Cas9-Mediated Correction of the Sickle Mutation in Human CD34+ cells.
Megan D Hoban, Dianne Lumaquin, Caroline Y Kuo, Zulema Romero, Joseph Long, Aaron R Cooper

Mol Ther· September 2016

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Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors.
Chee Jia Chin, Aaron R Cooper, Georgia R Lill, Denis Evseenko, Yuhua Zhu

Stem Cells· May 2016

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Reactivating Fetal Hemoglobin Expression in Human Adult Erythroblasts Through BCL11A Knockdown Using Targeted Endonucleases.
Carmen F Bjurström, Michelle Mojadidi, John Phillips, Caroline Kuo, Stephen Lai, Aaron Cooper

Mol Ther Nucleic Acids· January 2016

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The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells.
Zulema Romero, Beatriz Campo-Fernandez, Jennifer Wherley, Michael L Kaufman, Fabrizia Urbinati, Aaron R Cooper

Mol Ther Methods Clin Dev· June 2015

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Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy.
Kismet Baldwin, Fabrizia Urbinati, Zulema Romero, Beatriz Campo-Fernandez, Michael L Kaufman, Aaron R Cooper

Stem Cells· May 2015

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Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells.
Megan D Hoban, Gregory J Cost, Matthew C Mendel, Zulema Romero, Michael L Kaufman, Aaron R Cooper

Blood· April 2015

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Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter.
Aaron R Cooper, Georgia R Lill, Eric H Gschweng, Donald B Kohn

Nucleic Acids Res· January 2015

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Preclinical demonstration of lentiviral vector-mediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency.
Denise A Carbonaro, Lin Zhang, Xiangyang Jin, Claudia Montiel-Equihua, Sabine Geiger, Aaron Cooper

Mol Ther· March 2014

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Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells.
Tanya Stoyanova, Aaron R Cooper, Justin M Drake, Xian Liu, Andrew J Armstrong

Proc Natl Acad Sci U S A· December 2013

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β-globin gene transfer to human bone marrow for sickle cell disease.
Zulema Romero, Fabrizia Urbinati, Sabine Geiger, Aaron R Cooper, Jennifer Wherley

J Clin Invest· July 2013

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Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status.
Jason P Awe, Patrick C Lee, Cyril Ramathal, Agustin Vega-Crespo, Jens Durruthy-Durruthy, Aaron Cooper

Stem Cell Res Ther· July 2013

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Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene.
Melissa N McCracken, Eric H Gschweng, Evan Nair-Gill, Jami McLaughlin, Aaron R Cooper

Proc Natl Acad Sci U S A· January 2013

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