Publications by authors named "Aaron Ruff"

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Identification of M4205─A Highly Selective Inhibitor of KIT Mutations for Treatment of Unresectable Metastatic or Recurrent Gastrointestinal Stromal Tumors.
Andreas Blum, Dieter Dorsch, Nina Linde, Susanne Brandstetter, Hans-Peter Buchstaller, Aaron Ruff

J Med Chem· February 2023

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Model-Based Analysis of Biopharmaceutic Experiments To Improve Mechanistic Oral Absorption Modeling: An Integrated in Vitro in Vivo Extrapolation Perspective Using Ketoconazole as a Model Drug.
Shriram M Pathak, Aaron Ruff, Edmund S Kostewicz, Nikunjkumar Patel, David B Turner

Mol Pharm· December 2017

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Evaluating the predictability of the in vitro transfer model and in vivo rat studies as a surrogate to investigate the supersaturation and precipitation behaviour of different Albendazole formulations for humans.
Aaron Ruff, René Holm, Edmund S Kostewicz

Eur J Pharm Sci· July 2017

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Prediction of Ketoconazole absorption using an updated in vitro transfer model coupled to physiologically based pharmacokinetic modelling.
Aaron Ruff, Tom Fiolka, Edmund S Kostewicz

Eur J Pharm Sci· March 2017

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Advances and challenges in PBPK modeling--Analysis of factors contributing to the oral absorption of atazanavir, a poorly soluble weak base.
Mark Berlin, Aaron Ruff, Filippos Kesisoglou, Wei Xu, Michael Hong Wang

Eur J Pharm Biopharm· June 2015

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A toolbox for the upscaling of ethanolic human serum albumin (HSA) desolvation.
Matthias Wacker, Anja Zensi, Jürgen Kufleitner, Aaron Ruff, Jessica Schütz

Int J Pharm· July 2011

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