Publications by authors named "Abraham Shim"

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Activation and regulation of cGAS-STING signaling in cancer cells.
Abraham Shim, Yanyang Chen, John Maciejowski

Mol Cell· October 2025

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Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damage.
Rhiannon R Aguilar, Laiba F Khan, Christopher K Cummins, Nina Arslanovic, Thea Grauer, Abraham Shim

Nat Commun· September 2025

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Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against and , Two Emerging Human Pathogens.
Matheus Andrade Meirelles, Vitor M Almeida, Jaryd R Sullivan, Ian de Toledo, Caio Vinicius Dos Reis, Abraham Shim

J Med Chem· November 2024

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Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling.
Abraham Shim, Xiaohan Luan, Wen Zhou, Yanick J Crow, John Maciejowski

Hum Mol Genet· September 2024

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Intratumoral TREX1 Induction Promotes Immune Evasion by Limiting Type I IFN.
Eléonore Toufektchan, Alexandra Dananberg, Josefine Striepen, James H Hickling, Abraham Shim

Cancer Immunol Res· June 2024

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Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling.
Abraham Shim, Xiaohan Luan, Wen Zhou, Yanick Crow, John Maciejowski

bioRxiv· January 2024

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Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damage.
Rhiannon Aguilar, Laiba Khan, Nina Arslanovic, Kaylah Birmingham, Kritika Kasliwal, Abraham Shim

Res Sq· July 2023

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