Publications by authors named "Adam Cheuk"

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CAR-T cell expansion platforms yield distinct T cell differentiation states.
Hannah W Song, Michaela Prochazkova, Lipei Shao, Roshini Traynor, Sarah Underwood, Adam T Cheuk

Cytotherapy· July 2024

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CAR T-cells targeting FGFR4 and CD276 simultaneously show potent antitumor effect against childhood rhabdomyosarcoma.
Meijie Tian, Jun S Wei, Adam Tai-Chi Cheuk, David Milewski, Zhongmei Zhang

Nat Commun· July 2024

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Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma.
Meijie Tian, Jun S Wei, Nityashree Shivaprasad, Steven L Highfill, Berkley E Gryder, Adam T Cheuk

Cell Rep Med· May 2024

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Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma.
Meijie Tian, Jun S Wei, Nityashree Shivaprasad, Steven L Highfill, Berkley E Gryder, Adam T Cheuk

Cell Rep Med· October 2023

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A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia.
Katherine E Masih, Rebecca A Gardner, Hsien-Chao Chou, Abdalla Abdelmaksoud, Young K Song, Adam Tai-Chi Cheuk

Blood Adv· August 2023

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Preclinical Evaluation of the FGFR-Family Inhibitor Futibatinib for Pediatric Rhabdomyosarcoma.
Jerry T Wu, Adam Cheuk, Kristine Isanogle, Christina Robinson, Xiaohu Zhang

Cancers (Basel)· August 2023

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FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma.
Peter M Sullivan, Rajesh Kumar, Wei Li, Virginia Hoglund, Lingyan Wang, Adam Cheuk

Mol Cancer Ther· October 2022

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An optimized bicistronic chimeric antigen receptor against GPC2 or CD276 overcomes heterogeneous expression in neuroblastoma.
Meijie Tian, Adam T Cheuk, Jun S Wei, Abdalla Abdelmaksoud, Hsien-Chao Chou

J Clin Invest· August 2022

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Immunohistochemical detection of PAX-FOXO1 fusion proteins in alveolar rhabdomyosarcoma using breakpoint specific monoclonal antibodies.
David O Azorsa, Peter K Bode, Marco Wachtel, Adam Tai Chi Cheuk, Paul S Meltzer

Mod Pathol· April 2021

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Massively parallel sequencing reveals an accumulation of de novo mutations and an activating mutation of LPAR1 in a patient with metastatic neuroblastoma.
Jun S Wei, Peter Johansson, Li Chen, Young K Song, Catherine Tolman, Adam T C Cheuk

PLoS One· June 2014

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Targeting wild-type and mutationally activated FGFR4 in rhabdomyosarcoma with the inhibitor ponatinib (AP24534).
Samuel Q Li, Adam T Cheuk, Jack F Shern, Young K Song, Laura Hurd

PLoS One· May 2014

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CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells.
Jinping Jia, Allen D Bosley, Abbey Thompson, Jason W Hoskins, Adam Cheuk

Cancer Res· May 2014

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Synthetic lethal screen identifies NF-κB as a target for combination therapy with topotecan for patients with neuroblastoma.
Patricia S Tsang, Adam T Cheuk, Qing-Rong Chen, Young K Song, Thomas C Badgett

BMC Cancer· March 2012

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Systematic proteome analysis identifies transcription factor YY1 as a direct target of miR-34a.
Qing-Rong Chen, Li-Rong Yu, Patricia Tsang, Jun S Wei, Young K Song, Adam Cheuk

J Proteome Res· February 2011

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Screening a panel of drugs with diverse mechanisms of action yields potential therapeutic agents against neuroblastoma.
Jinesh S Gheeya, Qing-Rong Chen, Christopher D Benjamin, Adam T Cheuk, Patricia Tsang

Cancer Biol Ther· December 2009

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Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.
James G Taylor, Adam T Cheuk, Patricia S Tsang, Joon-Yong Chung, Young K Song

J Clin Invest· November 2009

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microRNA profiling identifies cancer-specific and prognostic signatures in pediatric malignancies.
Jun S Wei, Peter Johansson, Qing-Rong Chen, Young K Song, Steffen Durinck, Adam T C Cheuk

Clin Cancer Res· September 2009

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Anti-tumor immunity in a model of acute myeloid leukemia.
Adam T C Cheuk, James W Wells, Lucas Chan, Nigel B Westwood, Stuart A Berger

Leuk Lymphoma· March 2009

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Human neuroblastoma cells rapidly enter cell cycle arrest and apoptosis following exposure to C-28 derivatives of the synthetic triterpenoid CDDO.
Jennifer L Alabran, Adam Cheuk, Karen Liby, Michael Sporn, Javed Khan

Cancer Biol Ther· May 2008

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Immunotherapy of acute myeloid leukaemia: development of a whole cell vaccine.
Adam T C Cheuk, Barbara-ann Guinn

Front Biosci· January 2008

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Development of a whole cell vaccine for acute myeloid leukaemia.
Adam T C Cheuk, Lucas Chan, Barbara Czepulkowski, Stuart A Berger, Hideo Yagita

Cancer Immunol Immunother· January 2006

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Role of 4-1BB:4-1BB ligand in cancer immunotherapy.
Adam T C Cheuk, Ghulam J Mufti, Barbara-ann Guinn

Cancer Gene Ther· March 2004

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