Publications by authors named "Adam Drake"

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ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells.
Laura Carretero-Iglesia, Olivia J Hall, Jérémy Berret, Daniela Pais, Carole Estoppey, Adam Drake

Nat Cancer· October 2024

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Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma.
Blandine Pouleau, Carole Estoppey, Perrine Suere, Emilie Nallet, Amélie Laurendon, Adam Drake

Blood· July 2023

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Etavopivat, a Pyruvate Kinase Activator in Red Blood Cells, for the Treatment of Sickle Cell Disease.
Patricia Schroeder, Keertik Fulzele, Sanjeev Forsyth, Maria D Ribadeneira, Sylvie Guichard, Adam Drake

J Pharmacol Exp Ther· March 2022

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FT-4202, an oral PKR activator, has potent antisickling effects and improves RBC survival and Hb levels in SCA mice.
Archana Shrestha, Mengna Chi, Kimberly Wagner, Astha Malik, Jennifer Korpik, Adam Drake

Blood Adv· May 2021

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Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA.
Nathan Wan, David Weinberg, Tzu-Yu Liu, Katherine Niehaus, Eric A Ariazi, Adam M Drake

BMC Cancer· August 2019

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Induction and Therapeutic Targeting of Human NPM1c Myeloid Leukemia in the Presence of Autologous Immune System in Mice.
Mandeep Kaur, Adam C Drake, Guangan Hu, Stephen Rudnick, Qingfeng Chen

J Immunol· March 2019

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Interleukins 7 and 15 Maintain Human T Cell Proliferative Capacity through STAT5 Signaling.
Adam Drake, Mandeep Kaur, Bettina P Iliopoulou, Ryan Phennicie, Amanda Hanson

PLoS One· June 2017

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Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory.
Philipp Mews, Greg Donahue, Adam M Drake, Vincent Luczak, Ted Abel

Nature· June 2017

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Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.
Kristen E Pauken, Morgan A Sammons, Pamela M Odorizzi, Sasikanth Manne, Jernej Godec, Adam M Drake

Science· December 2016

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MLL1 is essential for the senescence-associated secretory phenotype.
Brian C Capell, Adam M Drake, Jiajun Zhu, Parisha P Shah, Zhixun Dou

Genes Dev· February 2016

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Autophagy mediates degradation of nuclear lamina.
Zhixun Dou, Caiyue Xu, Greg Donahue, Takeshi Shimi, Ji-An Pan, Adam M Drake

Nature· November 2015

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TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity.
Morgan A Sammons, Jiajun Zhu, Adam M Drake, Shelley L Berger

Genome Res· February 2015

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Sensitizing protective tumor microenvironments to antibody-mediated therapy.
Christian P Pallasch, Ilya Leskov, Christian J Braun, Daniela Vorholt, Adam Drake

Cell· January 2014

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Koch Institute Symposium on Cancer Immunology and Immunotherapy.
Adam Drake, Nikhil S Joshi, Gregory L Szeto, Eric Zhu, Herman N Eisen

Cancer Immunol Res· October 2013

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Of mice and men: what rodent models don't tell us.
Adam C Drake

Cell Mol Immunol· July 2013

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Rapid generation of human B-cell lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies.
Ilya Leskov, Christian P Pallasch, Adam Drake, Bettina P Iliopoulou, Amanda Souza

Oncogene· February 2013

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Engineering humanized mice for improved hematopoietic reconstitution.
Adam C Drake, Qingfeng Chen, Jianzhu Chen

Cell Mol Immunol· May 2012

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Graphene multilayers as gates for multi-week sequential release of proteins from surfaces.
Jinkee Hong, Nisarg J Shah, Adam C Drake, Peter C DeMuth, Jong Bum Lee

ACS Nano· January 2012

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Persistence of tumor-infiltrating CD8 T cells is tumor-dependent but antigen-independent.
Mobolaji O Olurinde, Ching-Hung Shen, Adam Drake, Ailin Bai, Jianzhu Chen

Cell Mol Immunol· September 2011

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Mesenchymal stem cells secreting angiopoietin-like-5 support efficient expansion of human hematopoietic stem cells without compromising their repopulating potential.
Maroun Khoury, Adam Drake, Qingfeng Chen, Di Dong, Ilya Leskov

Stem Cells Dev· August 2011

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Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2rγ-/- (NSG) mice.
Adam C Drake, Maroun Khoury, Ilya Leskov, Bettina P Iliopoulou, Maria Fragoso

PLoS One· April 2011

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Densely interconnected transcriptional circuits control cell states in human hematopoiesis.
Noa Novershtern, Aravind Subramanian, Lee N Lawton, Raymond H Mak, W Nicholas Haining, Adam C B Drake

Cell· January 2011

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Virus-specific host miRNAs: antiviral defenses or promoters of persistent infection?
Vinay S Mahajan, Adam Drake, Jianzhu Chen

Trends Immunol· January 2009

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Structural analysis of DNA-PKcs: modelling of the repeat units and insights into the detailed molecular architecture.
Suzanne C Brewerton, Andrew S Doré, Adam C B Drake, Kerstin K Leuther, Tom L Blundell

J Struct Biol· March 2004

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Identification of DNA-PK in the arthropods. Evidence for the ancient ancestry of vertebrate non-homologous end-joining.
Andrew S Doré, Adam C B Drake, Suzanne C Brewerton, Tom L Blundell

DNA Repair (Amst)· January 2004

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