Publications by authors named "Adam Irwin"

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A novel, standardised approach to balancing effectiveness, efficiency and utility of surveillance AI prediction models for hospitalised patients using sepsis prediction as an exemplar.
Anton H van der Vegt, Victoria K Campbell, Robert Webb, Balasubramanian Venkatesh, Paul J Lane, Adam Irwin

J Am Med Inform Assoc· November 2025

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Australian Group on Antimicrobial Resistance (AGAR) surveillance outcome programs - bloodstream infections and antimicrobial resistance patterns in Australian children and adolescents, January 2022 - December 2023.
Anita Williams, Geoffrey Coombs, Jan Bell, Denise Daley, Shakeel Mowlaboccus, Adam Irwin

Commun Dis Intell (2018)· November 2025

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Drug-resistant gram-negative bacterial infections in children in the Oceania region: review of the epidemiology, antimicrobial availability, treatment, clinical trial and pharmacokinetic data, and key evidence gaps.
Daniel K Yeoh, Alison Boast, Sophie Ch Wen, Phoebe Cm Williams, Lesley Voss, Adam D Irwin

Lancet Reg Health West Pac· November 2025

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Identifying a therapeutic target for ganciclovir against cytomegalovirus in immunocompromised children.
Wenyu Yang, Adam Irwin, Heather Weerdenburg, Brett McWhinney, Theresa Cole

Br J Clin Pharmacol· October 2025

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Corrigendum to "The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions" [Aust Crit Care 35 (2022) 651-660].
Jessica Schults, Karina Charles, Debbie Long, Georgia Brown, Beverley Copnell, Adam Irwin

Aust Crit Care· July 2025

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Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis.
Patricia Gilholm, Paula Lister, Adam Irwin, Amanda Harley, Sainath Raman

Matern Child Health J· May 2025

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Impact of COVID-19 on Antimicrobial Stewardship Activities in Hospitalised Children: A Scoping Review.
Zabiuddin Ahad Mohammed, Gary Grant, Adam D Irwin, Laetitia Hattingh, Vandana Kalwaje Eshwara

J Paediatr Child Health· March 2025

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Identification of distinct clinical profiles of sepsis risk in paediatric emergency department patients using Bayesian profile regression.
Patricia Gilholm, Sainath Raman, Adam Irwin, Paula Lister, Amanda Harley

BMJ Paediatr Open· March 2025

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A Rapid Molecular Detection Tool for Toxigenic M1UK  Streptococcus pyogenes.
Stephan Brouwer, Swairindhree Das, Andrew J Hayes, Olivia M Bertolla, Mark R Davies, Adam D Irwin

J Infect Dis· February 2025

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Antimicrobial Resistance in Staphylococcus aureus and Enterococcus spp. Isolates From Bloodstream Infections in Australian Children, 2013-2021.
Anita Williams, Geoffrey W Coombs, Jan M Bell, Denise A Daley, Shakeel Mowlaboccus, Adam D Irwin

J Pediatric Infect Dis Soc· February 2025

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Antimicrobial Resistance in Enterobacterales, Acinetobacter spp. and Pseudomonas aeruginosa Isolates From Bloodstream Infections in Australian Children, 2013-2021.
Anita Williams, Geoffrey W Coombs, Jan M Bell, Denise A Daley, Shakeel Mowlaboccus, Adam D Irwin

J Pediatric Infect Dis Soc· December 2024

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Serum ganciclovir drug exposure in children receiving standard ganciclovir dosing.
Wenyu Yang, Adam Irwin, Heather Weerdenburg, Brett McWhinney, Theresa Cole

Antimicrob Agents Chemother· October 2024

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Trends in Enterobacterales Bloodstream Infections in Children.
Anna A M Gibbs, Kevin B Laupland, Felicity Edwards, Weiping Ling, Samuel Channon-Wells, Adam D Irwin

Pediatrics· October 2024

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Characterization of Gram-negative Bloodstream Infections in Hospitalized Australian Children and Their Clinical Outcomes.
Sophie C H Wen, Patrick N A Harris, Brian Forde, Budi Permana, Mark D Chatfield, Adam D Irwin

Clin Infect Dis· September 2024

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Getting Up to Speed: Rapid Pathogen and Antimicrobial Resistance Diagnostics in Sepsis.
Mariana P Liborio, Patrick N A Harris, Chitra Ravi, Adam D Irwin

Microorganisms· September 2024

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Australian Group on Antimicrobial Resistance surveillance outcome programs - bloodstream infections and antimicrobial resistance patterns from patients less than 18 years of age, January 2020 - December 2021.
Anita Williams, Geoffrey W Coombs, Jan Bell, Denise A Daley, Shakeel Mowlaboccus, Adam D Irwin

Commun Dis Intell (2018)· August 2024

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Preventing adverse events during paediatric cancer treatment: protocol for a multi-site hybrid randomised controlled trial of catheter lock solutions (the CLOCK trial).
Amanda Ullman, Mari Takashima, Victoria Gibson, Elouise Comber, Eloise Borello, Adam Irwin

BMJ Open· July 2024

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Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study.
Luregn J Schlapbach, Devika Ganesamoorthy, Clare Wilson, Sainath Raman, Shane George, Adam Irwin

Lancet Child Adolesc Health· May 2024

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Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis.
Ming G Chai, Quyen Tu, Menino O Cotta, Michelle J Bauer, Ross Balch, Adam D Irwin

Intensive Care Med· May 2024

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Prevalence of extra-pulmonary tuberculosis in Africa: A systematic review and meta-analysis.
Semira Hailu, Cameron Hurst, Griffin Cyphers, Stefan Thottunkal, David Harley, Adam Irwin

Trop Med Int Health· April 2024

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Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis.
Ming G Chai, Quyen Tu, Menino O Cotta, Michelle J Bauer, Ross Balch, Adam D Irwin

Intensive Care Med· April 2024

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High-risk clones that cause neonatal meningitis and association with recrudescent infection.
Nguyen Thi Khanh Nhu, Minh-Duy Phan, Steven J Hancock, Kate M Peters, Laura Alvarez-Fraga, Adam D Irwin

Elife· April 2024

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Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis.
Patrick N A Harris, Michelle J Bauer, Lukas Lüftinger, Stephan Beisken, Brian M Forde, Adam D Irwin

Microbiol Spectr· February 2024

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A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria.
Nguyen Thi Khanh Nhu, M Arifur Rahman, Kelvin G K Goh, Seung Jae Kim, Minh-Duy Phan, Adam D Irwin

Nat Commun· February 2024

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Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infections.
Jessica A Schults, Karina R Charles, Jane Harnischfeger, Robert S Ware, Ruth H Royle, Adam Irwin

Aust Crit Care· January 2024

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