Publications by authors named "Adam J Tanner"

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Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis.
Philip N Collier, Heather C Twin, Ronald M A Knegtel, Dean Boyall, Guy Brenchley, Adam J Tanner

ACS Med Chem Lett· August 2019

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Design and optimization of selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases.
Juan-Miguel Jimenez, Dean Boyall, Guy Brenchley, Philip N Collier, Christopher J Davis, Adam J Tanner

J Med Chem· March 2013

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Discovery and structure-activity relationship of 3-aminopyrid-2-ones as potent and selective interleukin-2 inducible T-cell kinase (Itk) inhibitors.
Jean-Damien Charrier, Andrew Miller, David P Kay, Guy Brenchley, Heather C Twin, Adam J Tanner

J Med Chem· April 2011

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Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors.
Kieron Brown, Joanna M Long, Sarah C M Vial, Neesha Dedi, Nicholas J Dunster, Adam J Tanner

J Biol Chem· April 2004

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