Publications by authors named "Adam Kristopeit"

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CRISPR-Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin.
Jackson K B Cahn, Henry Ludwicki, Jillian Shingler, Shannon Gulvin, Young Zhang, Adam Kristopeit

Biotechnol Bioeng· August 2025

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A High-Throughput and Robust Relative Potency Assay Measuring Human Cytomegalovirus Infection in Epithelial Cells for Vaccine Development.
Nicole M Smiddy, Nisarg Patel, Matthew C Troutman, Kristine M Kearns, Zachary P Davis, Adam Kristopeit

Vaccines (Basel)· June 2025

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Purification processes of live virus vaccine candidates expressed in adherent Vero cell lines via multimodal chromatography in flowthrough mode.
Spyridon Konstantinidis, Murphy R Poplyk, Wanli Justin Ma, Devan Reilly, Young Zhang, Adam Kristopeit

Biotechnol Bioeng· August 2024

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Continuous multi-membrane chromatography of large viral particles.
Tiago Matos, David Hoying, Adam Kristopeit, Marc Wenger, Joseph Joyce

J Chromatogr A· August 2023

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Bacterial Retention During Filtration of a Live Attenuated Virus Vaccine Through the Sartobran P Sterile Filter.
Neil Taylor, Matt Morris, Alex Wee, Wanli Justin Ma, Adam Kristopeit

J Pharm Sci· July 2022

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Evaluating Nanoparticle Hydrophobicity Using Analytical Membrane Hydrophobic Interaction Chromatography.
Neil Taylor, Wanli Ma, Adam Kristopeit, Sheng-Ching Wang, Andrew L Zydney

Anal Chem· June 2022

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Characterization of gH/gL/pUL128-131 pentameric complex, gH/gL/gO trimeric complex, gB and gM/gN glycoproteins in a human cytomegalovirus using automated capillary western blots.
Richard R Rustandi, John W Loughney, Liang Shang, Shiyi Wang, Cindy J Pauley, Adam Kristopeit

Vaccine· July 2021

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Evaluation of a sterile filtration process for viral vaccines using a model nanoparticle suspension.
Neil Taylor, Wanli Ma, Adam Kristopeit, Sheng-Ching Wang, Andrew L Zydney

Biotechnol Bioeng· January 2021

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Structure of the cell-binding component of the binary toxin reveals a di-heptamer macromolecular assembly.
Xingjian Xu, Raquel Godoy-Ruiz, Kaylin A Adipietro, Christopher Peralta, Danya Ben-Hail, Adam Kristopeit

Proc Natl Acad Sci U S A· January 2020

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Ion-Exchange Chromatography to Analyze Components of a Clostridium difficile Vaccine.
Richard R Rustandi, Feng Wang, Catherine Lancaster, Adam Kristopeit, David S Thiriot

Methods Mol Biol· January 2018

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Development of a Novel Vaccine Containing Binary Toxin for the Prevention of Clostridium difficile Disease with Enhanced Efficacy against NAP1 Strains.
Susan Secore, Su Wang, Julie Doughtry, Jinfu Xie, Matt Miezeiewski, Adam Kristopeit

PLoS One· August 2017

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Toxicity assessment of Clostridium difficile toxins in rodent models and protection of vaccination.
Su Wang, Richard R Rustandi, Catherine Lancaster, Laura G Hong, David S Thiriot, Adam Kristopeit

Vaccine· March 2016

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Detecting and preventing reversion to toxicity for a formaldehyde-treated C. difficile toxin B mutant.
Bei Wang, Su Wang, Richard R Rustandi, Feng Wang, Christopher D Mensch, Adam Kristopeit

Vaccine· January 2015

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