Publications by authors named "Adam Lightfoot"

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The effect of simvastatin induced neurotoxicity on mitochondrial function in human neuronal cells.
Lauren Millichap, Nadia Turton, Razan Alomosh, Robert A Heaton, Amy Bateman, Adam P Lightfoot

Toxicol Mech Methods· July 2025

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A combination of major histocompatibility complex (MHC) I overexpression and type I interferon induce mitochondrial dysfunction in human skeletal myoblasts.
Anastasia Thoma, Razan Alomosh, Holly L Bond, Tania Akter-Miah, Nasser Al-Shanti, Adam P Lightfoot

J Cell Physiol· January 2025

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The Role of Mitochondria in Statin-Induced Myopathy.
Gavin Bell, Anastasia Thoma, Iain P Hargreaves, Adam P Lightfoot

Drug Saf· July 2024

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Major histocompatibility complex I-induced endoplasmic reticulum stress mediates the secretion of pro-inflammatory muscle-derived cytokines.
Anastasia Thoma, Kate E Earl, Katarzyna Goljanek-Whysall, Adam P Lightfoot

J Cell Mol Med· December 2022

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Cdk1-mediated threonine phosphorylation of Sam68 modulates its RNA binding, alternative splicing activity and cellular functions.
Idir Malki, Inara Liepina, Nora Kogelnik, Hollie Watmuff, Sue Robinson, Adam Lightfoot

Nucleic Acids Res· December 2022

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Internal Mammary Arteries as a Model to Demonstrate Restoration of the Impaired Vasodilation in Hypertension, Using Liposomal Delivery of the CYP1B1 Inhibitor, 2,3',4,5'-Tetramethoxystilbene.
Azziza Zaabalawi, Lewis Renshall, Frances Beards, Adam P Lightfoot, Hans Degens

Pharmaceutics· September 2022

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Nanostructured Lipid Carriers Deliver Resveratrol, Restoring Attenuated Dilation in Small Coronary Arteries, via the AMPK Pathway.
Cai Astley, Chahinez Houacine, Azziza Zaabalawi, Fiona Wilkinson, Adam P Lightfoot

Biomedicines· December 2021

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Cross-talk between motor neurons and myotubes via endogenously secreted neural and muscular growth factors.
Jasdeep Saini, Alessandro Faroni, Adam J Reid, Vincent Mouly, Gillian Butler-Browne, Adam P Lightfoot

Physiol Rep· April 2021

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A Novel Bioengineered Functional Motor Unit Platform to Study Neuromuscular Interaction.
Jasdeep Saini, Alessandro Faroni, Adam J Reid, Kamel Mamchaoui, Vincent Mouly, Adam P Lightfoot

J Clin Med· October 2020

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Targeting reactive oxygen species (ROS) to combat the age-related loss of muscle mass and function.
Anastasia Thoma, Tania Akter-Miah, Rebecca L Reade, Adam P Lightfoot

Biogerontology· August 2020

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Eukarion-134 Attenuates Endoplasmic Reticulum Stress-Induced Mitochondrial Dysfunction in Human Skeletal Muscle Cells.
Anastasia Thoma, Max Lyon, Nasser Al-Shanti, Gareth A Nye, Robert G Cooper, Adam P Lightfoot

Antioxidants (Basel)· August 2020

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MicroRNA and mRNA profiling in the idiopathic inflammatory myopathies.
Joanna E Parkes, Anastasia Thoma, Adam P Lightfoot, Philip J Day, Hector Chinoy

BMC Rheumatol· June 2020

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Tetramethoxystilbene-Loaded Liposomes Restore Reactive-Oxygen-Species-Mediated Attenuation of Dilator Responses in Rat Aortic Vessels Ex vivo.
Azziza Zaabalawi, Cai Astley, Lewis Renshall, Frances Beards, Adam P Lightfoot

Molecules· November 2019

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NF-kB and Inflammatory Cytokine Signalling: Role in Skeletal Muscle Atrophy.
Anastasia Thoma, Adam P Lightfoot

Adv Exp Med Biol· July 2019

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Simplified in vitro engineering of neuromuscular junctions between rat embryonic motoneurons and immortalized human skeletal muscle cells.
Jasdeep Saini, Alessandro Faroni, Marwah Abd Al Samid, Adam J Reid, Adam P Lightfoot

Stem Cells Cloning· February 2019

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Redox homeostasis and age-related deficits in neuromuscular integrity and function.
Giorgos K Sakellariou, Adam P Lightfoot, Kate E Earl, Martin Stofanko, Brian McDonagh

J Cachexia Sarcopenia Muscle· December 2017

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Muscling in on mitochondrial sexual dimorphism; role of mitochondrial dimorphism in skeletal muscle health and disease.
Gareth A Nye, Giorgos K Sakellariou, Hans Degens, Adam P Lightfoot

Clin Sci (Lond)· August 2017

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Post-exercise recovery regimes: blowing hot and cold.
Jamie S McPhee, Adam P Lightfoot

J Physiol· February 2017

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The role of myokines in muscle health and disease.
Adam P Lightfoot, Robert G Cooper

Curr Opin Rheumatol· November 2016

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Long-term administration of the mitochondria-targeted antioxidant mitoquinone mesylate fails to attenuate age-related oxidative damage or rescue the loss of muscle mass and function associated with aging of skeletal muscle.
Giorgos K Sakellariou, Timothy Pearson, Adam P Lightfoot, Gareth A Nye, Nicola Wells

FASEB J· November 2016

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Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy.
Giorgos K Sakellariou, Timothy Pearson, Adam P Lightfoot, Gareth A Nye, Nicola Wells

Sci Rep· September 2016

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Editorial: Endurance Exercise: An Important Therapeutic Adjuvant in the Overall Treatment of Myositis?
Adam P Lightfoot, Robert G Cooper

Arthritis Rheumatol· July 2016

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SS-31 attenuates TNF-α induced cytokine release from C2C12 myotubes.
Adam P Lightfoot, Giorgos K Sakellariou, Gareth A Nye, Francis McArdle, Malcolm J Jackson

Redox Biol· December 2015

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Response to: 'In the idiopathic inflammatory myopathies, reactive oxygen species are at the crossroad between immune and non-immune cell mediated mechanisms' by Meyer et al.
Adam P Lightfoot, Robert G Cooper

Ann Rheum Dis· November 2015

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Understanding the origin of non-immune cell-mediated weakness in the idiopathic inflammatory myopathies - potential role of ER stress pathways.
Adam P Lightfoot, Kanneboyina Nagaraju, Anne McArdle, Robert G Cooper

Curr Opin Rheumatol· November 2015

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