Publications by authors named "Adam Lopez"

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Proteomics Analysis on the Effects of Oxidative Stress and Antioxidants on Proteins Involved in Sterol Transport and Metabolism in Human Telomerase Transcriptase-Overexpressing-Retinal Pigment Epithelium Cells.
R Scott Duncan, Andrew Keightley, Adam A Lopez, Conner W Hall, Peter Koulen

Int J Mol Sci· October 2024

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Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism.
Shuai Tan, Jacobo L Santolaya, Tiffany Freeney Wright, Qi Liu, Teppei Fujikawa, Adam Lopez

Nat Metab· June 2024

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An enteroendocrine-microbial axis in the large intestine controls host metabolism.
Shuai Tan, Jacobo Santolaya, Tiffany Freeney Wright, Qi Liu, Teppei Fujikawa, Adam Lopez

Res Sq· July 2023

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Proteome changes in a human retinal pigment epithelial cell line during oxidative stress and following antioxidant treatment.
R Scott Duncan, Andrew Keightley, Adam A Lopez, Conner W Hall, Peter Koulen

Front Immunol· May 2023

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Molecular markers of brain cholesterol homeostasis are unchanged despite a smaller brain mass in a mouse model of cholesteryl ester storage disease.
Amal A Aqul, Charina M Ramirez, Adam M Lopez, Dennis K Burns, Joyce J Repa

Lipids· January 2022

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Estrogen Protects Optic Nerve Head Astrocytes Against Oxidative Stress by Preventing Caspase-3 Activation, Tau Dephosphorylation at Ser and the Formation of Tau Protein Aggregates.
John C Means, Adam A Lopez, Peter Koulen

Cell Mol Neurobiol· April 2021

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Paneth cell-derived growth factors support tumorigenesis in the small intestine.
Qing Chen, Kohei Suzuki, Luis Sifuentes-Dominguez, Naoteru Miyata, Jie Song, Adam Lopez

Life Sci Alliance· March 2021

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Regulation of murine copper homeostasis by members of the COMMD protein family.
Amika Singla, Qing Chen, Kohei Suzuki, Jie Song, Alina Fedoseienko, Adam Lopez

Dis Model Mech· January 2021

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Delineation of metabolic responses of Npc1 mice lacking the cholesterol-esterifying enzyme SOAT2 to acute treatment with 2-hydroxypropyl-β-cyclodextrin.
Charina M Ramirez, Anna M Taylor, Adam M Lopez, Joyce J Repa, Stephen D Turley

Steroids· December 2020

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Resveratrol Protects Optic Nerve Head Astrocytes from Oxidative Stress-Induced Cell Death by Preventing Caspase-3 Activation, Tau Dephosphorylation at Ser and Formation of Misfolded Protein Aggregates.
John C Means, Adam A Lopez, Peter Koulen

Cell Mol Neurobiol· August 2020

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Ontogenesis and Modulation of Intestinal Unesterified Cholesterol Sequestration in a Mouse Model of Niemann-Pick C1 Disease.
Adam M Lopez, Charina M Ramirez, Anna M Taylor, Ryan D Jones, Joyce J Repa

Dig Dis Sci· January 2020

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NK cell defects in X-linked pigmentary reticulate disorder.
Petro Starokadomskyy, Katelynn M Wilton, Konrad Krzewski, Adam Lopez, Luis Sifuentes-Dominguez

JCI Insight· November 2019

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Endosomal PI(3)P regulation by the COMMD/CCDC22/CCDC93 (CCC) complex controls membrane protein recycling.
Amika Singla, Alina Fedoseienko, Sai S P Giridharan, Brittany L Overlee, Adam Lopez

Nat Commun· September 2019

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Niemann-Pick C1-deficient mice lacking sterol O-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function.
Adam M Lopez, Ryan D Jones, Joyce J Repa, Stephen D Turley

Am J Physiol Gastrointest Liver Physiol· October 2018

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Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation.
Naoteru Miyata, Lindsey L Morris, Qing Chen, Curtis Thorne, Amika Singla, Adam Lopez

Cell Rep· August 2018

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Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/Mecp2 Mouse, a Model for Rett Syndrome.
Dieter Lütjohann, Adam M Lopez, Jen-Chieh Chuang, Anja Kerksiek, Stephen D Turley

Lipids· April 2018

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Measurement of Rates of Cholesterol and Fatty Acid Synthesis In Vivo Using Tritiated Water.
Adam M Lopez, Jen-Chieh Chuang, Stephen D Turley

Methods Mol Biol· February 2018

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Impact of loss of SOAT2 function on disease progression in the lysosomal acid lipase-deficient mouse.
Adam M Lopez, Jen-Chieh Chuang, Stephen D Turley

Steroids· February 2018

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Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase-deficient mice before and during treatment with ezetimibe.
Jen-Chieh Chuang, Adam M Lopez, Stephen D Turley

Biochem Pharmacol· July 2017

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'Corrigenda to "Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis" [Brain Res. 1654 (2017) 77-84]'.
Adam M Lopez, Jen-Chieh Chuang, Kenneth S Posey, Stephen D Turley

Brain Res· February 2017

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Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis.
Adam M Lopez, Jen-Chieh Chuang, Kenneth S Posey, Stephen D Turley

Brain Res· January 2017

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PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice.
Adam M Lopez, Jen-Chieh Chuang, Kenneth S Posey, Taichi Ohshiro, Hiroshi Tomoda

J Pharmacol Exp Ther· November 2015

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Lysosomal Acid Lipase Activity: A Tool for the Detection and Management of Fatty Liver Disease?
Charina M Ramirez, Adam M Lopez, Stephen D Turley

EBioMedicine· July 2015

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Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice.
Ryan D Jones, Adam M Lopez, Ernest Y Tong, Kenneth S Posey, Jen-Chieh Chuang

Steroids· January 2015

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Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small intestine and liver.
Adam M Lopez, Kenneth S Posey, Stephen D Turley

Biochem Biophys Res Commun· November 2014

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