Publications by authors named "Adam MacLean"

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The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brain.
Lauryn A Higginson, Xingjun Wang, Kevin He, Maggie Torstrick, Minhoo Kim, Adam MacLean

Cell Rep· December 2025

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Gene regulatory network inference with popInfer reveals the dynamic regulation of hematopoietic stem cell quiescence.
Megan K Rommelfanger, Marthe Behrends, Yulin Chen, Jonathan Martinez, Nikith Kurella, Adam L MacLean

iScience· December 2025

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Beyond RECIST: mathematical modeling and Bayesian inference reveal the importance of immune parameters in metastatic breast cancer.
Jesse Kreger, Edgar Gonzalez, Xiaojun Wu, Evanthia T Roussos Torres, Adam L MacLean

bioRxiv· August 2025

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Transition paths across the epithelial-mesenchymal transition landscape are dictated by network logic.
Anupam Dey, Adam L MacLean

Development· June 2025

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Cancer systems immunology reveals myeloid-T cell interactions and B cell activation mediate response to checkpoint inhibition in metastatic breast cancer.
Edgar Gonzalez, Jesse Kreger, Yingtong Liu, Xiaojun Wu, Arianna Barbetta, Adam L MacLean

bioRxiv· June 2025

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Longitudinal single cell RNA-sequencing reveals evolution of micro- and macro-states in chronic myeloid leukemia.
David E Frankhouser, Dandan Zhao, Yu-Hsuan Fu, Anupam Dey, Ziang Chen, Adam L MacLean

bioRxiv· May 2025

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Modeling the dynamics of EMT reveals genes associated with pan-cancer intermediate states and plasticity.
MeiLu McDermott, Riddhee Mehta, Evanthia T Roussos Torres, Adam L MacLean

NPJ Syst Biol Appl· April 2025

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Data-driven model discovery and model selection for noisy biological systems.
Xiaojun Wu, MeiLu McDermott, Adam L MacLean

PLoS Comput Biol· January 2025

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Transition paths across the EMT landscape are dictated by network logic.
Anupam Dey, Adam L MacLean

bioRxiv· December 2024

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Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life.
Jesse Kreger, Jazlyn A Mooney, Darryl Shibata, Adam L MacLean

Nat Commun· November 2024

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A new Neu-a syngeneic model of spontaneously metastatic HER2-positive breast cancer.
Aaron G Baugh, Edgar Gonzalez, Valerie H Narumi, Jesse Kreger, Yingtong Liu, Adam MacLean

Clin Exp Metastasis· October 2024

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Intratumoral CXCL12 Gradients Contextualize Tumor Cell Invasion, Migration and Immune Suppression in Breast Cancer.
Dimitra P Anastasiadou, Nicole Couturier, Sakshi Goel, Dimitrios G Argyris, Stepan Vodopyanov, Adam L MacLean

bioRxiv· October 2024

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The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brain.
Lauryn A Higginson, Xingjun Wang, Kevin He, Maggie Torstrick, Minhoo Kim, Adam MacLean

bioRxiv· October 2024

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Hematopoietic stem cell aging by the niche.
Adam L MacLean, K Lenhard Rudolph

Blood· July 2024

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Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life.
Jesse Kreger, Jazlyn A Mooney, Darryl Shibata, Adam L MacLean

bioRxiv· March 2024

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Gastrulation-stage gene expression in mouse embryos foreshadows the development of syndromic birth defects.
Stephenson Chea, Jesse Kreger, Martha E Lopez-Burks, Adam L MacLean, Arthur D Lander

Sci Adv· March 2024

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Gastrulation-stage gene expression in mouse embryos foreshadows the development of syndromic birth defects.
Stephenson Chea, Jesse Kreger, Martha E Lopez-Burks, Adam L MacLean, Arthur D Lander

bioRxiv· February 2024

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Mimicking the breast metastatic microenvironment: characterization of a novel syngeneic model of HER2 breast cancer.
Aaron G Baugh, Edgar Gonzalez, Valerie H Narumi, Jesse Kreger, Yingtong Liu, Adam MacLean

bioRxiv· January 2024

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Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney.
Lingyun Xiong, Jing Liu, Seung Yub Han, Kari Koppitch, Jin-Jin Guo, Adam L MacLean

Dev Cell· November 2023

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Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis.
Gerald Coulis, Diego Jaime, Christian Guerrero-Juarez, Jenna M Kastenschmidt, Philip K Farahat, Adam L MacLean

Sci Adv· July 2023

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Single-cell Ca parameter inference reveals how transcriptional states inform dynamic cell responses.
Xiaojun Wu, Roy Wollman, Adam L MacLean

J R Soc Interface· June 2023

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Author Correction: Julia for biologists.
Elisabeth Roesch, Joe G Greener, Adam L MacLean, Huda Nassar, Christopher Rackauckas

Nat Methods· May 2023

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Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney.
Lingyun Xiong, Jing Liu, Seung Yub Han, Kari Koppitch, Jin-Jin Guo, Adam L MacLean

bioRxiv· May 2023

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Gene regulatory network inference with popInfer reveals dynamic regulation of hematopoietic stem cell quiescence upon diet restriction and aging.
Megan K Rommelfanger, Marthe Behrends, Yulin Chen, Jonathan Martinez, Martin Bens, Adam L MacLean

bioRxiv· April 2023

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Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis.
Gerald Coulis, Diego Jaime, Christian Guerrero-Juarez, Jenna M Kastenschmidt, Philip K Farahat, Adam L MacLean

bioRxiv· April 2023

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