Publications by authors named "Adam Mead"

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Investigation and management of thrombocytosis without JAK2, CALR or MPL mutations: A British Society for Haematology Guideline.
Anna L Godfrey, Alesia A Khan, Andrew McGregor, Andrew J Innes, Mohammed Altohami, Adam J Mead

Br J Haematol· December 2025

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Causal relevance of clonal haematopoiesis with cardiac disease and adverse remodelling: a Mendelian randomisation study.
Alec Peter Morley, Maddalena Ardissino, Paul Carter, Betty Raman, Adam J Mead

Open Heart· October 2025

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SFX-01 is therapeutic against myeloproliferative disorders caused by activating mutations in Shp2.
Hyun-Ju Cho, Joy Smith, Christopher H Switzer, Eleni Louka, Rebecca L Charles, Adam J Mead

EMBO Mol Med· August 2025

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Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA.
Lauren Murphy, Jeanne Inchauspé, Giampiero Valenzano, Pamela Holland, Nikolaos Sousos, Adam J Mead

Science· August 2025

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Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML.
Zhe Wang, Anna Skwarska, Gowri Poigaialwar, Sovira Chaudhry, Alba Rodriguez-Meira, Adam J Mead

Blood· July 2025

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Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A.
Charlotte K Brierley, Bon Ham Yip, Giulia Orlando, Jeremy Wen, Sean Wen, Adam J Mead

Nat Genet· June 2025

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Tumor-Infiltrating Clonal Hematopoiesis.
Oriol Pich, Elsa Bernard, Maria Zagorulya, Andrew Rowan, Constandina Pospori, Adam J Mead

N Engl J Med· April 2025

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Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial.
Graham McIlroy, Charlotte Gaskell, Aimee Jackson, Emily Yafai, Rachel Tasker, Adam J Mead

BMC Cancer· January 2025

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Treatment of the blood cancer polycythemia vera with ruxolitinib in the MAJIC-PV study: a plain language summary.
Claire N Harrison, Sonia Fox, Rebecca Boucher, Mary Frances McMullin, Adam J Mead

Future Oncol· December 2024

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Molecular profiling in MPN: who should have it and why?
Ashlyn Chee, Adam J Mead

Hematology Am Soc Hematol Educ Program· December 2024

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Clinical utility of investigations in triple-negative thrombocytosis: A real-world, multicentre evaluation of UK practice.
Anna L Godfrey, Nikolaos Sousos, Rebecca Frewin, Mahesh Prahladan, Anna C Green, Adam J Mead

Br J Haematol· October 2024

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A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis.
Rong Li, Michela Colombo, Guanlin Wang, Antonio Rodriguez-Romera, Camelia Benlabiod, Adam J Mead

Sci Transl Med· October 2024

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Safety and efficacy of luspatercept for the treatment of anemia in patients with myelofibrosis.
Aaron T Gerds, Claire Harrison, Jean-Jacques Kiladjian, Ruben Mesa, Alessandro M Vannucchi, Adam J Mead

Blood Adv· September 2024

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Predictive Performance of Cardiovascular Risk Scores in Cancer Survivors From the UK Biobank.
Celeste McCracken, Dorina-Gabriela Condurache, Liliana Szabo, Hussein Elghazaly, Fiona M Walter, Adam J Mead

JACC CardioOncol· August 2024

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Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells.
Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen, Christoph Ziegenhain, Adam J Mead

Nat Immunol· June 2024

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Meaningful Symptomatic Change in Patients With Myelofibrosis From the SIMPLIFY Studies.
Stacie Hudgens, Srdan Verstovsek, Lysbeth Floden, Claire N Harrison, Jeanne Palmer, Adam J Mead

Value Health· May 2024

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Backtracking to the future: unraveling the origins of childhood leukemia.
Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy

Leukemia· February 2024

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Changes in bone marrow fibrosis during momelotinib or ruxolitinib therapy do not correlate with efficacy outcomes in patients with myelofibrosis.
Stephen T Oh, Srdan Verstovsek, Vikas Gupta, Uwe Platzbecker, Timothy Devos, Adam J Mead

EJHaem· February 2024

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Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts.
Pedro L Moura, Teresa Mortera-Blanco, Isabel J Hofman, Gabriele Todisco, Warren W Kretzschmar, Adam J Mead

Cancer Res· January 2024

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Diagnosis and evaluation of prognosis of myelofibrosis: A British Society for Haematology Guideline.
Donal P McLornan, Anna L Godfrey, Anna Green, Rebecca Frewin, Siamak Arami, Adam Mead

Br J Haematol· January 2024

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Outcomes and characteristics of nonmelanoma skin cancers in patients with myeloproliferative neoplasms on ruxolitinib.
Alex Rampotas, Luke Carter-Brzezinski, Tim C P Somervaille, James Forryan, Fotios Panitsas, Adam J Mead

Blood· January 2024

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The management of myelofibrosis: A British Society for Haematology Guideline.
Donal P McLornan, Bethan Psaila, Joanne Ewing, Andrew Innes, Siamak Arami, Adam Mead

Br J Haematol· January 2024

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Patient-reported Outcomes and Quality of Life in Anemic and Symptomatic Patients With Myelofibrosis: Results From the MOMENTUM Study.
Ruben A Mesa, Claire Harrison, Jeanne M Palmer, Vikas Gupta, Donal P McLornan, Adam J Mead

Hemasphere· November 2023

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Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis.
Zijian Fang, Giuditta Corbizi Fattori, Thomas McKerrell, Rebecca H Boucher, Aimee Jackson, Adam J Mead

Nat Commun· November 2023

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Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Tiago C Luis, Nikolaos Barkas, Joana Carrelha, Alice Giustacchini, Stefania Mazzi, Adam J Mead

Nat Commun· September 2023

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