Publications by authors named "Adam N Goldfarb"

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Arterial iron regulates vasodilation during anemia via endothelial holo-alpha globin.
Luke S Dunaway, Shruthi Nyshadham, Wyatt J Schug, Skylar Loeb, Brooke O'Donnel, Adam N Goldfarb

bioRxiv· December 2025

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Chromatin structure and 3D architecture define the differential functions of PU.1 regulatory elements in blood cell lineages.
Kevin Qiu, Duc C Vu, Leran Wang, Nicholas N Nguyen, Anna K Bookstaver, Adam N Goldfarb

Epigenetics Chromatin· November 2024

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Transcriptional Regulation of the Lineage-Determining Gene in Normal and Malignant Hematopoiesis: Current Understanding and Therapeutic Perspective.
Emilia A Korczmar, Anna K Bookstaver, Ellison Ober, Adam N Goldfarb, Daniel G Tenen

Front Biosci (Schol Ed)· May 2024

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Chromatin structure and 3D architecture define differential functions of cis regulatory elements in human blood cell lineages.
Kevin Qiu, Duc Vu, Leran Wang, Anna Bookstaver, Thang N Dinh, Adam N Goldfarb

bioRxiv· January 2024

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Liver kinase B1 (LKB1) in murine erythroid progenitors modulates erythropoietin setpoint in association with maturation control.
Zollie White, Kamaleldin E Elagib, Alejandro A Gru, Adam N Goldfarb

Blood Cells Mol Dis· November 2022

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Relieving DYRK1A repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes.
Kamaleldin E Elagib, Ashton Brock, Cara M Clementelli, Goar Mosoyan, Lorrie L Delehanty, Adam N Goldfarb

J Clin Invest· October 2022

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Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia.
Adam N Goldfarb, Katie C Freeman, Ranjit K Sahu, Kamaleldin E Elagib, Maja Holy

Nat Commun· March 2021

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levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance.
Peter Balogh, Emmalee R Adelman, John V Pluvinage, Brian J Capaldo, Katie C Freeman, Adam N Goldfarb

Haematologica· April 2020

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Megakaryocyte ontogeny: Clinical and molecular significance.
Kamaleldin E Elagib, Ashton T Brock, Adam N Goldfarb

Exp Hematol· May 2018

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Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.
Kamaleldin E Elagib, Chih-Huan Lu, Goar Mosoyan, Shadi Khalil, Ewelina Zasadzińska, Adam N Goldfarb

J Clin Invest· June 2017

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Erratum for Elagib et al., Jun Blockade of Erythropoiesis: Role for Repression of GATA-1 by HERP2.
Kamaleldin E Elagib, Mang Xiao, Isa M Hussaini, Lorrie L Delehanty, Lisa A Palmer, Adam N Goldfarb

Mol Cell Biol· June 2015

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Megakaryocytic irreversible P-TEFb activation.
Kamaleldin E Elagib, Adam N Goldfarb

Cell Cycle· January 2015

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Calpain 2 activation of P-TEFb drives megakaryocyte morphogenesis and is disrupted by leukemogenic GATA1 mutation.
Kamaleldin E Elagib, Jeremy D Rubinstein, Lorrie L Delehanty, Valerie S Ngoh, Peter A Greer, Adam N Goldfarb

Dev Cell· December 2013

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Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response.
Chanté L Richardson, Lorrie L Delehanty, Grant C Bullock, Claudia M Rival, Kenneth S Tung, Adam N Goldfarb

J Clin Invest· August 2013

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Protein kinase D-HDAC5 signaling regulates erythropoiesis and contributes to erythropoietin cross-talk with GATA1.
Lorrie L Delehanty, Grant C Bullock, Adam N Goldfarb

Blood· November 2012

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Cyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis.
Jeremy D Rubinstein, Kamaleldin E Elagib, Adam N Goldfarb

J Biol Chem· June 2012

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Aconitase regulation of erythropoiesis correlates with a novel licensing function in erythropoietin-induced ERK signaling.
Anne-Laure Talbot, Grant C Bullock, Lorrie L Delehanty, Martin Sattler, Zhizhuang Joe Zhao, Adam N Goldfarb

PLoS One· February 2012

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Iron control of erythroid development by a novel aconitase-associated regulatory pathway.
Grant C Bullock, Lorrie L Delehanty, Anne-Laure Talbot, Sara L Gonias, Wing-Hang Tong, Adam N Goldfarb

Blood· July 2010

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Coordinating red cell differentiation with cell cycle arrest: GATA-1 activation of p21.
Adam N Goldfarb

Cell Cycle· June 2010

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Megakaryocytic programming by a transcriptional regulatory loop: A circle connecting RUNX1, GATA-1, and P-TEFb.
Adam N Goldfarb

J Cell Biochem· June 2009

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Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation.
Jing-Ruey J Yeh, Kathleen M Munson, Kamaleldin E Elagib, Adam N Goldfarb, David A Sweetser

Nat Chem Biol· April 2009

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Cross-talk of GATA-1 and P-TEFb in megakaryocyte differentiation.
Kamaleldin E Elagib, Ivailo S Mihaylov, Lorrie L Delehanty, Grant C Bullock, Kevin D Ouma, Adam N Goldfarb

Blood· December 2008

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Regulation of RUNX1 transcriptional function by GATA-1.
Kamaleldin E Elagib, Adam N Goldfarb

Crit Rev Eukaryot Gene Expr· October 2007

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Oncogenic pathways of AML1-ETO in acute myeloid leukemia: multifaceted manipulation of marrow maturation.
Kamaleldin E Elagib, Adam N Goldfarb

Cancer Lett· June 2007

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Erythroid inhibition by the leukemic fusion AML1-ETO is associated with impaired acetylation of the major erythroid transcription factor GATA-1.
Youngjin Choi, Kamaleldin E Elagib, Lorrie L Delehanty, Adam N Goldfarb

Cancer Res· March 2006

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