Publications by authors named "Adam Steg"

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The use of hedgehog antagonists in cancer therapy: a comparison of clinical outcomes and gene expression analyses.
Burthia E Booker, Adam D Steg, Stefan Kovac, Charles N Landen, Hope M Amm

Cancer Biol Ther· October 2020

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Targeting RNA-Polymerase I in Both Chemosensitive and Chemoresistant Populations in Epithelial Ovarian Cancer.
Robert Cornelison, Zachary C Dobbin, Ashwini A Katre, Dae Hoon Jeong, Yinfeng Zhang, Adam D Steg

Clin Cancer Res· November 2017

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The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activity.
Ashley L Spann, Kun Yuan, Kayla F Goliwas, Adam D Steg, Devanshu D Kaushik

Int J Oncol· July 2015

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Simple regression for correcting ΔCt bias in RT-qPCR low-density array data normalization.
Xiangqin Cui, Shaohua Yu, Ashutosh Tamhane, Zenoria L Causey, Adam Steg

BMC Genomics· February 2015

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Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer.
Zachary C Dobbin, Ashwini A Katre, Adam D Steg, Britt K Erickson, Monjri M Shah

Oncotarget· September 2014

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Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer.
Adam D Steg, Mata R Burke, Hope M Amm, Ashwini A Katre, Zachary C Dobbin

Oncotarget· August 2014

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Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer.
Angela J Ziebarth, Somaira Nowsheen, Adam D Steg, Monjri M Shah, Ashwini A Katre

Clin Cancer Res· January 2013

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Smoothened antagonists reverse taxane resistance in ovarian cancer.
Adam D Steg, Ashwini A Katre, Kerri S Bevis, Angela Ziebarth, Zachary C Dobbin

Mol Cancer Ther· July 2012

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Differential expression of breast cancer-associated genes between stage- and age-matched tumor specimens from African- and Caucasian-American Women diagnosed with breast cancer.
Jessica M Grunda, Adam D Steg, Qinghua He, Mark R Steciuk, Suzanne Byan-Parker

BMC Res Notes· May 2012

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Stem cell pathways contribute to clinical chemoresistance in ovarian cancer.
Adam D Steg, Kerri S Bevis, Ashwini A Katre, Angela Ziebarth, Zachary C Dobbin

Clin Cancer Res· February 2012

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Targeting the notch ligand JAGGED1 in both tumor cells and stroma in ovarian cancer.
Adam D Steg, Ashwini A Katre, Blake Goodman, Hee-Dong Han, Alpa M Nick

Clin Cancer Res· September 2011

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Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell lines.
Yeon-Jin Kwon, Douglas R Hurst, Adam D Steg, Kun Yuan, Kedar S Vaidya

Clin Exp Metastasis· June 2011

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Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells.
Hope M Amm, Tong Zhou, Adam D Steg, Huichien Kuo, Yufeng Li

Mol Cancer Res· April 2011

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Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer.
Charles N Landen, Blake Goodman, Ashwini A Katre, Adam D Steg, Alpa M Nick

Mol Cancer Ther· December 2010

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Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer.
Adam Steg, Hope M Amm, Zdenek Novak, Andra R Frost, Martin R Johnson

Cancer Biol Ther· November 2010

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Primary cilia are decreased in breast cancer: analysis of a collection of human breast cancer cell lines and tissues.
Kun Yuan, Natalya Frolova, Yi Xie, Dezhi Wang, Leah Cook, Adam D Steg

J Histochem Cytochem· October 2010

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Gli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer.
Lusheng Xu, Yeon-Jin Kwon, Natalya Frolova, Adam D Steg, Kun Yuan

Breast Cancer Res Treat· August 2010

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Hedgehog pathway expression in heterogeneous pancreatic adenocarcinoma: implications for the molecular analysis of clinically available biopsies.
Adam Steg, Selwyn M Vickers, Mohamad Eloubeidi, Wenquan Wang, Isam A Eltoum

Diagn Mol Pathol· December 2007

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Long-term survival on capecitabine in two gemcitabine refractory pancreatic cancer patients. Is there a pharmacogenetic explanation?
Muhammad Wasif Saif, Soonmo Peter Kang, Leslie Ledbetter, Adam Steg, Robert Diasio

JOP· November 2007

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Phase II study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: up-regulation of thymidine phosphorylase.
Muhammad Wasif Saif, Glenda Black, Shalija Roy, Diana Bell, Suzanne Russo, Adam Steg

Cancer J· October 2007

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Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM).
Jessica M Grunda, L Burton Nabors, Cheryl A Palmer, David C Chhieng, Adam Steg

J Neurooncol· December 2006

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Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.
Shibani Mukherjee, Natalya Frolova, Andrea Sadlonova, Zdenek Novak, Adam Steg

Cancer Biol Ther· June 2006

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Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma.
Adam Steg, Wenquan Wang, Carmelo Blanquicett, Jessica M Grunda, Isam A Eltoum

J Mol Diagn· February 2006

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Phase I study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: expression analysis of genes related to outcome.
M Wasif Saif, Mohammaed A Eloubeidi, Suzanne Russo, Adam Steg, Jennifer Thornton

J Clin Oncol· December 2005

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