Publications by authors named "Addmore Shonhai"

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A promising class of antiprotozoal agents, design and synthesis of novel Pyrimidine-Cinnamoyl hybrids.
Francis Kayamba, Rajshekhar Karpoormath, Vincent A Obakachi, Mavela Mahlalela, Danny Banda, Addmore Shonhai

Eur J Med Chem· January 2025

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Auto QSAR-based active learning docking for hit identification of potential inhibitors of Plasmodium falciparum Hsp90 as antimalarial agents.
Thato Matlhodi, Lisema Patrick Makatsela, Tendamudzimu Harmfree Dongola, Mthokozisi Blessing Cedric Simelane, Addmore Shonhai

PLoS One· November 2024

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Ursolic acid acetate and iso-mukaadial acetate bind to Plasmodium falciparum Hsp90, abrogating its chaperone function in vitro.
Andani A T Nndwammbi, Tendamudzimu Harmfree Dongola, Addmore Shonhai, Fortunate Mokoena, Ofentse J Pooe

Naunyn Schmiedebergs Arch Pharmacol· July 2024

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Swapping the linkers of canonical Hsp70 and Hsp110 chaperones compromises both self-association and client selection.
Graham Chakafana, Caitlin J Middlemiss, Tawanda Zininga, Addmore Shonhai

Heliyon· May 2024

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Plasmodium falciparum heat shock proteins as antimalarial drug targets: An update.
Tanveer Ahmad, Bushra A Alhammadi, Shaikha Y Almaazmi, Sahar Arafa, Gregory L Blatch, Addmore Shonhai

Cell Stress Chaperones· April 2024

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Iso-mukaadial acetate and ursolic acid acetate bind to Plasmodium Falciparum heat shock protein 70: towards targeting parasite protein folding pathway.
Francis Opoku, Penny Govender, Addmore Shonhai, Mthokozisi Bc Simelane

BMC Chem· March 2024

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Escherichia coli-based Complementation Assay to Study the Chaperone Function of Heat Shock Protein 70.
Hloniphani Rachel Ncube, Unarine Dali, Tendamudzimu Harmfree Dongola, Addmore Shonhai

J Vis Exp· March 2024

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Insertion of GGMP repeat residues of Plasmodium falciparum Hsp70-1 in the lid of DnaK adversely impacts client recognition.
Tendamudzimu Harmfree Dongola, Graham Chakafana, Caitlin Middlemiss, Ofentse Mafethe, Fortunate Mokoena, Addmore Shonhai

Int J Biol Macromol· January 2024

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Correction: Bopape et al. The Genome of a Pigeonpea Compatible Rhizobial Strain '10ap3' Appears to Lack Common Nodulation Genes. 2023, , 1084.
Francina L Bopape, Ahmed Idris Hassen, Rogerio M Chiulele, Addmore Shonhai, Eastonce T Gwata

Genes (Basel)· January 2024

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The multi-faceted roles of R2TP complex span across regulation of gene expression, translation, and protein functional assembly.
Sifiso Duncan Luthuli, Addmore Shonhai

Biophys Rev· December 2023

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Pharmacophore Model-Based Virtual Screening Workflow for Discovery of Inhibitors Targeting Hsp90.
Ofentse Mafethe, Tlhalefo Ntseane, Tendamudzimu Harmfree Dongola, Addmore Shonhai, Njabulo Joyfull Gumede

ACS Omega· October 2023

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Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro.
Lebogang Ramatsui, Tendamudzimu Harmfree Dongola, Tawanda Zininga, Gabriele Multhoff, Addmore Shonhai

Cell Stress Chaperones· May 2023

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The Genome of a Pigeonpea Compatible Rhizobial Strain '10ap3' Appears to Lack Common Nodulation Genes.
Francina L Bopape, Ahmed Idris Hassen, Rogerio M Chiulele, Addmore Shonhai, Eastonce T Gwata

Genes (Basel)· May 2023

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2-Hydroxypropyl-β-cyclodextrin (HPβCD) as a Potential Therapeutic Agent for Breast Cancer.
Sourav Taru Saha, Naaziyah Abdulla, Tawanda Zininga, Addmore Shonhai, Reubina Wadee

Cancers (Basel)· May 2023

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Inhibition of Hsp70-Hop partnership by 2-phenylthynesulfonamide.
Tshifhiwa Muthelo, Vhahangwele Mulaudzi, Munei Netshishivhe, Tendamudzimu Harmfree Dongola, Michelle Kok, Addmore Shonhai

Front Mol Biosci· September 2022

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Host cell stress response as a predictor of COVID-19 infectivity and disease progression.
Celine Caillet, Melissa Louise Stofberg, Victor Muleya, Addmore Shonhai, Tawanda Zininga

Front Mol Biosci· August 2022

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The Role of Hsp70s in the Development and Pathogenicity of Plasmodium falciparum.
Addmore Shonhai

Adv Exp Med Biol· September 2021

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Bioprospecting for Novel Heat Shock Protein Modulators: The New Frontier for Antimalarial Drug Discovery?
Chinedu Anokwuru, Stanley Makumire, Addmore Shonhai

Adv Exp Med Biol· September 2021

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Heat Shock Proteins of Malaria: Highlights and Future Prospects.
Addmore Shonhai, Gregory L Blatch

Adv Exp Med Biol· September 2021

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Supporting data on characterisation of linker switch mutants of heat shock protein 110 and canonical Hsp70.
Graham Chakafana, Pertunia T Mudau, Tawanda Zininga, Addmore Shonhai

Data Brief· August 2021

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Characterisation of a unique linker segment of the Plasmodium falciparum cytosol localised Hsp110 chaperone.
Graham Chakafana, Pertunia T Mudau, Tawanda Zininga, Addmore Shonhai

Int J Biol Macromol· June 2021

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Characterization of an Atypical Hsp70 Demonstrates Its Cytosolic-Nuclear Localization and Modulation by Quercetin and Methylene Blue.
Adélle Burger, Paula Macucule-Tinga, Stephen John Bentley, Michael Hans Ludewig, Ndumiso Nhlakanipho Mhlongo, Addmore Shonhai

Int J Mol Sci· June 2021

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Heat Shock Proteins: Potential Modulators and Candidate Biomarkers of Peripartum Cardiomyopathy.
Graham Chakafana, Timothy F Spracklen, Stephen Kamuli, Tawanda Zininga, Addmore Shonhai

Front Cardiovasc Med· June 2021

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Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors.
Francis Kayamba, Teboho Malimabe, Idowu Kehinde Ademola, Ofentse Jacob Pooe, Narva Deshwar Kushwaha, Addmore Shonhai

Eur J Med Chem· May 2021

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'Meet the editor series'-Addmore Shonhai.
Addmore Shonhai

Biophys Rev· April 2021

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