Publications by authors named "Adel A Marzouk"

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A new approach for the development of etodolac emulgels for rheumatic arthritis cure: and assessments.
Shaaban K Osman, Ahmed M Mohammed, Khaled I Saleh, Taher M Yassin, Ahmed M Abdelsalam, Adel A Marzouk

Drug Dev Ind Pharm· November 2025

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Design, Synthesis, and Mechanistic Study of Novel Ciprofloxacin/Thiazole Chalcone Hybrids as Potential Anticancer Agents.
Hamada Hashem, Ali M Elshamsy, Safwat M Rabea, Adel A Marzouk, Stefan Bräse

Pharmaceuticals (Basel)· November 2025

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Development and Validation of an HPLC-UV/PDA Method for the Determination of Cannflavins in Different Chemovars.
Mostafa A Elhendawy, Mohamed M Radwan, Elsayed A Ibrahim, Amira S Wanas, Adel A Marzouk

Methods Protoc· September 2025

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Synthesis, antiproliferative evaluation and studies of new quinazoline derivatives as VEGFR-2 inhibitors.
Abdelsalam Mohamed Abdelsalam Ouf, Adel A Marzouk, Montaser Sh A Shaykoon, Ismail Celik, Dina A Bakhotmah

Future Med Chem· June 2025

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Isolation and investigation of cannflavins from leaves as potential anti-SARS-CoV-2 agents targeting the Papain-Like Protease.
Amira S Wanas, Mohamed M Radwan, Adel A Marzouk, Eslam B Elkaeed, Bshra A Alsfouk

Nat Prod Res· March 2025

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Novel guanidine derivatives targeting leukemia as selective Src/Abl dual inhibitors: Design, synthesis and anti-proliferative activity.
Amr H Moustafa, Asmaa M AboulMagd, Ali M Ali, Ahmed Khodairy, Adel A Marzouk

Bioorg Chem· June 2024

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Tailored Tetrasubstituted Imidazole Carrying the Benzenesulfonamide Fragments as Selective Human Carbonic Anhydrase IX/XII Inhibitors.
Ehab S Taher, Adel A Marzouk, Walaa Hamada Abd-Allah, Simone Giovannuzzi, Tarek S Ibrahim

ChemMedChem· May 2024

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Development and Assessment of 1,5-Diarylpyrazole/Oxime Hybrids Targeting EGFR and JNK-2 as Antiproliferative Agents: A Comprehensive Study through Synthesis, Molecular Docking, and Evaluation.
Kamal S Abdelrahman, Heba A Hassan, Salah A Abdel-Aziz, Adel A Marzouk, Raef Shams

Molecules· September 2023

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Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition.
Mohammed M Amin, Gamal El-Din A Abuo-Rahma, Montaser Sh A Shaykoon, Adel A Marzouk, Mohammed A S Abourehab

Bioorg Chem· May 2023

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Anticancer Activities of Tetrasubstituted Imidazole-Pyrimidine-Sulfonamide Hybrids as Inhibitors of EGFR Mutants.
Eman M Alghamdi, Zahra M Alamshany, Mohamed A El Hamd, Ehab S Taher, Mohammed Farrag El-Behairy, Adel A Marzouk

ChemMedChem· April 2023

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A Polymer-based Monolithic Capillary Column with Polymyxin-B Chiral Selector for the Enantioselective Nano-High Performance Liquid Chromatographic Pharmaceutical Analysis.
Ashraf Ghanem, Adel A Marzouk, Sobhy M El-Adl, Ali Fouad

J Chromatogr A· January 2022

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Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Fluorinated Candidates as PI3K Inhibitors: Targeting Fluorophilic Binding Sites.
Ahmed H Tantawy, Mohammed Farrag El-Behairy, Walaa Hamada Abd-Allah, Hong Jiang, Man-Qun Wang, Adel A Marzouk

J Med Chem· December 2021

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Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Tri-Aryl Imidazole-Benzene Sulfonamide Hybrids as Promising Selective Carbonic Anhydrase IX and XII Inhibitors.
Lamya H Al-Wahaibi, Bahaa G M Youssif, Ehab S Taher, Ahmed H Abdelazeem, Antar A Abdelhamid, Adel A Marzouk

Molecules· August 2021

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Synthesis, DFT Calculations, Antiproliferative, Bactericidal Activity and Molecular Docking of Novel Mixed-Ligand Salen/8-Hydroxyquinoline Metal Complexes.
Badriah Saad Al-Farhan, Maram T Basha, Laila H Abdel Rahman, Ahmed M M El-Saghier, Doaa Abou El-Ezz, Adel A Marzouk

Molecules· August 2021

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Structure-based design, synthesis, and biological evaluation of novel piperine-resveratrol hybrids as antiproliferative agents targeting SIRT-2.
Ahmed H Tantawy, Xiang-Gao Meng, Adel A Marzouk, Ali Fouad, Ahmed H Abdelazeem

RSC Adv· July 2021

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Design, synthesis, biological evaluation, and computational studies of novel thiazolo-pyrazole hybrids as promising selective COX-2 inhibitors: Implementation of apoptotic genes expression for ulcerogenic liability assessment.
Adel A Marzouk, Ehab S Taher, Montaser Sh A Shaykoon, Ping Lan, Walaa Hamada Abd-Allah

Bioorg Chem· June 2021

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Daptomycin: A Novel Macrocyclic Antibiotic as a Chiral Selector in an Organic Polymer Monolithic Capillary for the Enantioselective Analysis of a Set of Pharmaceuticals.
Ali Fouad, Adel A Marzouk, Montaser Sh A Shaykoon, Samy M Ibrahim, Sobhy M El-Adl

Molecules· June 2021

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JNK signaling as a target for anticancer therapy.
Kamal S Abdelrahman, Heba A Hassan, Salah A Abdel-Aziz, Adel A Marzouk, Atsushi Narumi

Pharmacol Rep· April 2021

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Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors.
Lamya H Al-Wahaibi, Amer A Amer, Adel A Marzouk, Hesham A M Gomaa, Bahaa G M Youssif

Pharmaceuticals (Basel)· April 2021

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Design and synthesis of pyrimidine-5-carbonitrile hybrids as COX-2 inhibitors: Anti-inflammatory activity, ulcerogenic liability, histopathological and docking studies.
Abdallah M Alfayomy, Salah A Abdel-Aziz, Adel A Marzouk, Montaser Sh A Shaykoon, Atsushi Narumi

Bioorg Chem· March 2021

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Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors.
Mamdouh F A Mohamed, Adel A Marzouk, Ayman Nafady, Dalia A El-Gamal, Rasha M Allam

Bioorg Chem· December 2020

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Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity.
Mohamed T M Nemr, Amr Sonousi, Adel A Marzouk

Bioorg Chem· December 2020

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Design and synthesis of new 1,6-dihydropyrimidin-2-thio derivatives targeting VEGFR-2: Molecular docking and antiproliferative evaluation.
Adel A Marzouk, Salah A Abdel-Aziz, Kamal S Abdelrahman, Amira S Wanas, Ahmed M Gouda

Bioorg Chem· September 2020

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Design, synthesis and anticonvulsant activity of new imidazolidindione and imidazole derivatives.
Adel A Marzouk, Amr K A Bass, Montaser Sh Ahmed, Antar A Abdelhamid, Yaseen A M M Elshaier

Bioorg Chem· August 2020

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Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives.
Montaser Sh Shaykoon, Adel A Marzouk, Osama M Soltan, Amira S Wanas, Mohamed M Radwan

Bioorg Chem· July 2020

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