Publications by authors named "Adham Bear"

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Mutant KRAS peptide targeted CAR-T cells engineered for cancer therapy.
Alexander Benton, Jiageng Liu, Mathilde A Poussin, Andrea Lang Goldgewicht, Madhara Udawela, Adham S Bear

Cancer Cell· July 2025

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LOXHD1 is an oncofusion-regulated antigen of ewing sarcoma.
Tatiana Blanchard, Pouya Faridi, Chong Xu, Adham S Bear, Reyaz Ur Rasool

Sci Rep· April 2025

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Identification of Core Techniques That Enhance Genome Editing of Human T Cells Expressing Synthetic Antigen Receptors.
Ju-Fang Chang, Nils Wellhausen, Nils W Engel, Jack H Landmann, Caitlin R Hopkins, Adham S Bear

Cancer Immunol Res· September 2024

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Natural TCRs targeting KRASG12V display fine specificity and sensitivity to human solid tumors.
Adham S Bear, Rebecca B Nadler, Mark H O'Hara, Kelsey L Stanton, Chong Xu

J Clin Invest· September 2024

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Facts and Hopes in Immunotherapy Strategies Targeting Antigens Derived from KRAS Mutations.
Gerald P Linette, Adham S Bear, Beatriz M Carreno

Clin Cancer Res· May 2024

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Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.
Anže Smole, Alexander Benton, Mathilde A Poussin, Monika A Eiva, Claudia Mezzanotte, Adham S Bear

Cancer Cell· December 2022

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Concurrent Nab-paclitaxel and Radiotherapy: Novel Radiosensitization for Borderline Resectable or Unresectable Pancreatic Cancer.
William T Arscott, Kevin T Nead, Adham Bear, Sriram Venigalla, Jacob Shabason

Am J Clin Oncol· September 2021

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Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
Adham S Bear, Tatiana Blanchard, Joseph Cesare, Michael J Ford, Lee P Richman

Nat Commun· July 2021

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Tumor-Derived Myeloid Cell Chemoattractants and T Cell Exclusion in Pancreatic Cancer.
Robert H Vonderheide, Adham S Bear

Front Immunol· June 2021

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Adoptive Cellular Therapy for Solid Tumors.
Adham S Bear, Joseph A Fraietta, Vivek K Narayan, Mark O'Hara, Naomi B Haas

Am Soc Clin Oncol Educ Book· March 2021

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Challenges and Opportunities for Pancreatic Cancer Immunotherapy.
Adham S Bear, Robert H Vonderheide, Mark H O'Hara

Cancer Cell· December 2020

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Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model.
Daniel L Galvan, Richard T O'Neil, Aaron E Foster, Leslie Huye, Adham Bear

PLoS One· June 2016

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Low rate of infusional toxicity after expanded cord blood transplantation.
Adham S Bear, Patrick J Hanley, Doyle M Bosque, Conrad R Cruz, Indresh Kaur

Cytotherapy· August 2014

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Elimination of metastatic melanoma using gold nanoshell-enabled photothermal therapy and adoptive T cell transfer.
Adham S Bear, Laura C Kennedy, Joseph K Young, Serena K Perna, Joao Paulo Mattos Almeida

PLoS One· March 2014

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Gold nanoparticle delivery of modified CpG stimulates macrophages and inhibits tumor growth for enhanced immunotherapy.
Adam Yuh Lin, Joao Paulo Mattos Almeida, Adham Bear, Nathan Liu, Laureen Luo

PLoS One· January 2014

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An adaptable system for improving transposon-based gene expression in vivo via transient transgene repression.
Joseph E Doherty, Lauren E Woodard, Adham S Bear, Aaron E Foster, Matthew H Wilson

FASEB J· September 2013

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High-density sub-100-nm peptide-gold nanoparticle complexes improve vaccine presentation by dendritic cells in vitro.
Adam Yuh Lin, Jessica Lunsford, Adham Sean Bear, Joseph Keith Young, Phillip Eckels

Nanoscale Res Lett· February 2013

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T cells as vehicles for cancer vaccination.
Adham S Bear, Conrad R Cruz, Aaron E Foster

J Biomed Biotechnol· March 2012

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Replication-competent retroviruses in gene-modified T cells used in clinical trials: is it time to revise the testing requirements?
Adham S Bear, Richard A Morgan, Kenneth Cornetta, Carl H June, Gwendolyn Binder-Scholl

Mol Ther· February 2012

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T cells enhance gold nanoparticle delivery to tumors in vivo.
Laura C Kennedy, Adham S Bear, Joseph K Young, Nastassja A Lewinski, Jean Kim

Nanoscale Res Lett· April 2011

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IRAK-M removal counteracts dendritic cell vaccine deficits in migration and longevity.
Meghan E Turnis, Xiao-Tong Song, Adham Bear, Aaron E Foster, Stephen Gottschalk

J Immunol· October 2010

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Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b.
John A Craddock, An Lu, Adham Bear, Martin Pule, Malcolm K Brenner

J Immunother· October 2010

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Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes.
Anjum S Kaka, Donald R Shaffer, Ryan Hartmaier, Ann M Leen, An Lu, Adham Bear

J Immunother· September 2009

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