Publications by authors named "Aditya Murthy"

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From lab-to-clinic with model informed formulation development: a case study of hydroxyzine SR tablets.
Aditya Murthy, Shubham Jamdade, Manoj Gundeti, Maddukuri Harika, Rahul Chiliveri

Xenobiotica· May 2025

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Advancements in Ocular Modelling and Simulations: Key Considerations and Case Studies.
Mohammed Shareef Khan, Aditya Murthy, Tausif Ahmed

AAPS PharmSciTech· December 2024

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Systematic perturbation screens identify regulators of inflammatory macrophage states and a role for TNF mRNA m6A modification.
Simone M Haag, Shiqi Xie, Celine Eidenschenk, Jean-Philippe Fortin, Marinella Callow, Aditya Murthy

Nat Genet· November 2024

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Modeling kinematic variability reveals displacement and velocity based dual control of saccadic eye movements.
Varsha Vasudevan, Aditya Murthy, Radhakant Padhi

Exp Brain Res· September 2024

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Evaluating gender effect in the generic bioequivalence studies by physiologically based pharmacokinetic modeling - A case study of dextromethorphan modified release tablets.
Manoj Gundeti, Aditya Murthy, Shubham Jamdade, Tausif Ahmed

Biopharm Drug Dispos· June 2024

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Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer.
Lucia Taraborrelli, Yasin Şenbabaoğlu, Lifen Wang, Junghyun Lim, Kerrigan Blake, Aditya Murthy

Nat Commun· September 2023

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Velocity tracking control best explains the modulation of saccade kinematics during eye-hand coordination.
Varsha Vasudevan, Atul Gopal, Sumitash Jana, Radhakant Padhi, Aditya Murthy

Eur J Neurosci· July 2023

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Modelling Based Approaches to Support Generic Drug Regulatory Submissions-Practical Considerations and Case Studies.
Prajwala Karnati, Aditya Murthy, Manoj Gundeti, Tausif Ahmed

AAPS J· June 2023

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Context-specific early recruitment of small motor units in the shoulder muscle reflects a reach movement plan.
Satya Rungta, Aditya Murthy

J Neurophysiol· May 2023

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Optimized Nonviral Gene Disruption in Primary Murine and Human Myeloid Cells.
Emily C Freund, Simone M Haag, Benjamin Haley, Aditya Murthy

Methods Mol Biol· March 2023

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Albumin-hitchhiking: Fostering the pharmacokinetics and anticancer therapeutics.
Paras Famta, Saurabh Shah, Naitik Jain, Dadi A Srinivasarao, Aditya Murthy

J Control Release· January 2023

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Neck muscle activity reflects neural patterns of sequential saccade planning in head-restrained primates.
Debaleena Basu, Naveen Sendhilnathan, Aditya Murthy

J Neurophysiol· October 2022

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Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.
Dennis X Hu, Snahel Patel, Huifen Chen, Shumei Wang, Steven T Staben, Aditya Murthy

J Med Chem· September 2022

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A Novel Approach to Justify Dissolution Differences in an Extended Release Drug Product using Physiologically Based Biopharmaceutics Modeling and Simulation.
R Aishwarya, Aditya Murthy, Tausif Ahmed, Siddharth Chachad

J Pharm Sci· June 2022

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Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation.
Ofer Guttman, Adrien Le Thomas, Scot Marsters, David A Lawrence, Lauren Gutgesell, Aditya Murthy

J Cell Biol· June 2022

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Neural mechanisms underlying the temporal control of sequential saccade planning in the frontal eye field.
Debaleena Basu, Naveen Sendhilnathan, Aditya Murthy

Proc Natl Acad Sci U S A· October 2021

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Preparatory activity links the frontal eye field response with small amplitude motor unit recruitment of neck muscles during gaze planning.
Satya Rungta, Debaleena Basu, Naveen Sendhilnathan, Aditya Murthy

J Neurophysiol· August 2021

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Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response.
Timurs Maculins, Erik Verschueren, Trent Hinkle, Meena Choi, Patrick Chang, Aditya Murthy

Elife· June 2021

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Computational Mechanisms Mediating Inhibitory Control of Coordinated Eye-Hand Movements.
Sumitash Jana, Atul Gopal, Aditya Murthy

Brain Sci· May 2021

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Murine Monocyte and Macrophage Culture.
Simone M Haag, Aditya Murthy

Bio Protoc· March 2021

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Neural correlates of goal-directed and non-goal-directed movements.
Naveen Sendhilnathan, Debaleena Basu, Michael E Goldberg, Jeffrey D Schall, Aditya Murthy

Proc Natl Acad Sci U S A· February 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Aditya Murthy

Autophagy· January 2021

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Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage.
Andrew P AhYoung, Sterling C Eckard, Alvin Gogineni, Hongkang Xi, S Jack Lin, Aditya Murthy

Commun Biol· November 2020

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Perceptual Priming Can Increase or Decrease With Aging.
Kalathupiriyan A Zhivago, Sneha Shashidhara, Ranjini Garani, Simran Purokayastha, Naren P Rao, Aditya Murthy

Front Aging Neurosci· November 2020

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Targeting Autophagy to Treat Cancer: Challenges and Opportunities.
Junghyun Lim, Aditya Murthy

Front Pharmacol· November 2020

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