Publications by authors named "Adrian Biddle"

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Identification of Phenotypically Distinct Cancer Stem Cell Subpopulations in Oral Squamous Cell Carcinoma.
Tarig Al-Hadi Osman, Oddveig Rikardsen, Muy-Teck Teh, Dipak Sapkota, Kristina Xiao Liang, Adrian Biddle

Cancers (Basel)· November 2025

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A CD24CD271 melanoma cancer stem cell possesses hybrid characteristics of its single marker counterparts and promotes invasion and therapeutic resistance.
Olivia Knowles, Patricio Doldan, Isabella Hillier-Richardson, Sophia Lunetto, Stephanie Lunt, Adrian Biddle

BMC Biol· August 2025

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The nucleosome remodeling and deacetylase-SWItch/sucrose non-fermentable antagonism regulates the coordinated activation of epithelial-to-mesenchymal transition and inflammation in oral cancer.
Roberto Stabile, Francesco A Tucci, Mathijs P Verhagen, Carmen Embregts, Thierry P P van den Bosch, Adrian Biddle

J Natl Cancer Inst· July 2025

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Development of an microfluidic model to study the role of microenvironmental cells in oral cancer metastasis.
Alice Scemama, Sophia Lunetto, Artysha Tailor, Stefania Di Cio, Matthew Dibble, Adrian Biddle

F1000Res· March 2024

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Disseminating cells in human oral tumours possess an EMT cancer stem cell marker profile that is predictive of metastasis in image-based machine learning.
Gehad Youssef, Luke Gammon, Leah Ambler, Sophia Lunetto, Alice Scemama, Adrian Biddle

Elife· November 2023

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CD73 controls Myosin II-driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells.
Remi Samain, Oscar Maiques, Joanne Monger, Hoyin Lam, Juliana Candido, Adrian Biddle

Sci Adv· October 2023

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In vitro cancer models as an approach to identify targetable developmental phenotypes in cancer stem cells.
Adrian Biddle

In Vitro Model· May 2023

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Highlight: microfluidic devices for cancer metastasis studies.
Alice Scemama, Sophia Lunetto, Adrian Biddle

In Vitro Model· December 2022

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Organ-on-a-Chip Technologies Network special issue editorial.
Adrian Biddle

In Vitro Model· December 2022

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Cancer stem cell plasticity and its implications in the development of new clinical approaches for oral squamous cell carcinoma.
Henry Marles, Adrian Biddle

Biochem Pharmacol· October 2022

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Interconnected high-dimensional landscapes of epithelial-mesenchymal plasticity and stemness in cancer.
Sarthak Sahoo, Bazella Ashraf, Atchuta Srinivas Duddu, Adrian Biddle, Mohit Kumar Jolly

Clin Exp Metastasis· April 2022

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Portrait of a CAF: The story of cancer-associated fibroblasts in head and neck cancer.
Marcos Custódio, Adrian Biddle, Mahvash Tavassoli

Oral Oncol· November 2020

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Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas.
Mohit Kumar Jolly, Jason A Somarelli, Maya Sheth, Adrian Biddle, Satyendra C Tripathi

Pharmacol Ther· February 2019

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Effects of Cetuximab and Erlotinib on the behaviour of cancer stem cells in head and neck squamous cell carcinoma.
Maria Fernanda Setúbal Destro Rodrigues, Luke Gammon, Muhammad M Rahman, Adrian Biddle, Fabio Daumas Nunes

Oncotarget· March 2018

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Reprogramming to developmental plasticity in cancer stem cells.
Caitlin O'Brien-Ball, Adrian Biddle

Dev Biol· October 2017

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Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma.
Adrian Biddle, Luke Gammon, Xiao Liang, Daniela Elena Costea, Ian C Mackenzie

EBioMedicine· February 2016

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Invasive oral cancer stem cells display resistance to ionising radiation.
Emilios Gemenetzidis, Luke Gammon, Adrian Biddle, Helena Emich, Ian C Mackenzie

Oncotarget· December 2015

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Phenotypic plasticity and epithelial-to-mesenchymal transition in the behaviour and therapeutic response of oral squamous cell carcinoma.
Navin Vig, Ian C Mackenzie, Adrian Biddle

J Oral Pathol Med· October 2015

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Elevation in 5-FU-induced apoptosis in head and neck cancer stem cells by a combination of CDHP and GSK3β inhibitors.
Hideo Shigeishi, Adrian Biddle, Luke Gammon, Camila O Rodini, Miho Yamasaki

J Oral Pathol Med· March 2015

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Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism.
Luke Gammon, Adrian Biddle, Hannah K Heywood, Anne C Johannessen, Ian C Mackenzie

PLoS One· November 2013

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Expression of betapapillomavirus oncogenes increases the number of keratinocytes with stem cell-like properties.
Martin Hufbauer, Adrian Biddle, Cinzia Borgogna, Marisa Gariglio, John Doorbar

J Virol· November 2013

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Maintenance of stem cell self-renewal in head and neck cancers requires actions of GSK3β influenced by CD44 and RHAMM.
Hideo Shigeishi, Adrian Biddle, Luke Gammon, Helena Emich, Camila O Rodini

Stem Cells· October 2013

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CD44 staining of cancer stem-like cells is influenced by down-regulation of CD44 variant isoforms and up-regulation of the standard CD44 isoform in the population of cells that have undergone epithelial-to-mesenchymal transition.
Adrian Biddle, Luke Gammon, Bilal Fazil, Ian C Mackenzie

PLoS One· August 2013

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Cancer stem cells and EMT in carcinoma.
Adrian Biddle, Ian C Mackenzie

Cancer Metastasis Rev· February 2012

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Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative.
Adrian Biddle, Xiao Liang, Luke Gammon, Bilal Fazil, Lisa J Harper

Cancer Res· August 2011

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