Publications by authors named "Adrian Bird"

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Modelling transcription with explainable AI uncovers context-specific epigenetic gene regulation at promoters and gene bodies.
Kashyap Chhatbar, Adrian Bird, Guido Sanguinetti

PLoS Genet· October 2025

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Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach.
Jacky Guy, Elena Hein, Bea Alexander-Howden, Timur von Bock Und Polach, Tricia Mathieson, Adrian Bird

bioRxiv· September 2025

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Cohesin as an essential disruptor of chromosome organization.
Adrian Bird

Mol Cell· March 2025

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MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation.
Raphaël Pantier, Megan Brown, Sicheng Han, Katie Paton, Stephen Meek, Adrian Bird

Nat Commun· May 2024

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Loss of CpG island immunity to DNA methylation induced by mutation.
Bernhard Horsthemke, Adrian Bird

Epigenetics Chromatin· May 2023

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Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome.
James A Watson, Raphaël Pantier, Uma Jayachandran, Kashyap Chhatbar, Beatrice Alexander-Howden, Adrian Bird

Life Sci Alliance· March 2023

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A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay.
Beatrice Alexander-Howden, Li Zhang, Almer M van der Sloot, Sylvain Tollis, Daniel J St-Cyr, Adrian P Bird

Sci Rep· March 2023

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A critique of the hypothesis that CA repeats are primary targets of neuronal MeCP2.
Kashyap Chhatbar, John Connelly, Shaun Webb, Skirmantas Kriaucionis, Adrian Bird

Life Sci Alliance· December 2022

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High-throughput sequencing SELEX for the determination of DNA-binding protein specificities in vitro.
Raphaël Pantier, Kashyap Chhatbar, Grace Alston, Heng Yang Lee, Adrian Bird

STAR Protoc· September 2022

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Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome.
Stephanie A Zlatic, Duc Duong, Kamal K E Gadalla, Brenda Murage, Lingyan Ping, Adrian Bird

iScience· September 2022

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Comparative analysis of potential broad-spectrum neuronal Cre drivers.
Katie M Paton, Jim Selfridge, Jacky Guy, Adrian Bird

Wellcome Open Res· July 2022

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Genetic therapies for neurological disorders.
Laura FitzPatrick, Adrian Bird

Hum Genet· May 2022

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CDKL5 deficiency disorder: a pathophysiology of neural maintenance.
Peter C Kind, Adrian Bird

J Clin Invest· November 2021

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Neuronal non-CG methylation is an essential target for MeCP2 function.
Rebekah Tillotson, Justyna Cholewa-Waclaw, Kashyap Chhatbar, John C Connelly, Sophie A Kirschner, Adrian Bird

Mol Cell· March 2021

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SALL4 controls cell fate in response to DNA base composition.
Raphaël Pantier, Kashyap Chhatbar, Timo Quante, Konstantina Skourti-Stathaki, Justyna Cholewa-Waclaw, Adrian Bird

Mol Cell· February 2021

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Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing.
Kashyap Chhatbar, Justyna Cholewa-Waclaw, Ruth Shah, Adrian Bird, Guido Sanguinetti

PLoS Genet· October 2020

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Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo.
John C Connelly, Justyna Cholewa-Waclaw, Shaun Webb, Verdiana Steccanella, Bartlomiej Waclaw, Adrian Bird

Nucleic Acids Res· April 2020

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DNA Methylation: Mega-Year Inheritance with the Help of Darwin.
Adrian Bird

Curr Biol· April 2020

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The Molecular Basis of MeCP2 Function in the Brain.
Rebekah Tillotson, Adrian Bird

J Mol Biol· March 2020

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The Selfishness of Law-Abiding Genes.
Adrian Bird

Trends Genet· January 2020

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Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic.
Justyna Cholewa-Waclaw, Ruth Shah, Shaun Webb, Kashyap Chhatbar, Bernard Ramsahoye, Adrian P Bird

Proc Natl Acad Sci U S A· July 2019

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R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes.
Konstantina Skourti-Stathaki, Elena Torlai Triglia, Marie Warburton, Philipp Voigt, Adrian Bird

Mol Cell· March 2019

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An Orphan CpG Island Drives Expression of a miRNA Precursor with an Important Role in Mouse Development.
Martha V Koerner, Kashyap Chhatbar, Shaun Webb, Justyna Cholewa-Waclaw, Jim Selfridge, Adrian Bird

Epigenomes· March 2019

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Toxicity of overexpressed MeCP2 is independent of HDAC3 activity.
Martha V Koerner, Laura FitzPatrick, Jim Selfridge, Jacky Guy, Dina De Sousa, Adrian Bird

Genes Dev· December 2018

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Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2.
Matthew J Lyst, Robert Ekiert, Jacky Guy, Jim Selfridge, Martha V Koerner, Adrian Bird

Cell Rep· August 2018

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