Publications by authors named "Adrian G Todd"

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Neonatal systemic gene therapy restores cardiorespiratory function in a rat model of Pompe disease.
David D Fuller, Sabhya Rana, Prajwal P Thakre, Ethan S Benevides, Megan K Pope, Adrian G Todd

Mol Ther· September 2025

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Neonatal systemic gene therapy restores cardiorespiratory function in a rat model of Pompe disease.
David D Fuller, Sabhya Rana, Prajwal Thakre, Ethan Benevides, Megan Pope, Adrian G Todd

bioRxiv· December 2024

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HSP90 Inhibitor, NVP-AUY922, Improves Myelination in Vitro and Supports the Maintenance of Myelinated Axons in Neuropathic Mice.
Vinita G Chittoor-Vinod, Hannah Bazick, Adrian G Todd, Darin Falk, Kathryn H Morelli

ACS Chem Neurosci· June 2019

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Locomotor and skeletal muscle abnormalities in trembler J neuropathic mice.
Darin J Falk, Tori Galatas, Adrian G Todd, Elliott P Soto, Andrew B Harris

Muscle Nerve· April 2018

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C/P MRS Metabolic Biomarkers of Disease Progression and Response to AAV Delivery of hGAA in a Mouse Model of Pompe Disease.
Celine Baligand, Adrian G Todd, Brittany Lee-McMullen, Ravneet S Vohra, Barry J Byrne

Mol Ther Methods Clin Dev· December 2017

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Copackaged AAV9 Vectors Promote Simultaneous Immune Tolerance and Phenotypic Correction of Pompe Disease.
Phillip A Doerfler, Adrian G Todd, Nathalie Clément, Darin J Falk, Sushrusha Nayak

Hum Gene Ther· January 2016

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Correcting Neuromuscular Deficits With Gene Therapy in Pompe Disease.
Adrian G Todd, Jessica A McElroy, Robert W Grange, David D Fuller, Glenn A Walter

Ann Neurol· August 2015

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Comparative impact of AAV and enzyme replacement therapy on respiratory and cardiac function in adult Pompe mice.
Darin J Falk, Meghan S Soustek, Adrian Gary Todd, Cathryn S Mah, Denise A Cloutier

Mol Ther Methods Clin Dev· June 2015

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Peripheral nerve and neuromuscular junction pathology in Pompe disease.
Darin J Falk, Adrian Gary Todd, Sooyeon Lee, Meghan S Soustek, Mai K ElMallah

Hum Mol Genet· February 2015

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Rapamycin improves peripheral nerve myelination while it fails to benefit neuromuscular performance in neuropathic mice.
Jessica Nicks, Sooyeon Lee, Andrew Harris, Darin J Falk, Adrian G Todd

Neurobiol Dis· October 2014

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Dilysine motifs in exon 2b of SMN protein mediate binding to the COPI vesicle protein α-COP and neurite outgrowth in a cell culture model of spinal muscular atrophy.
Sara K Custer, Adrian G Todd, Natalia N Singh, Elliot J Androphy

Hum Mol Genet· October 2013

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COPI transport complexes bind to specific RNAs in neuronal cells.
Adrian G Todd, Hai Lin, Allison D Ebert, Yunlong Liu, Elliot J Androphy

Hum Mol Genet· February 2013

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Using mini-genes to identify factors that modulate alternative splicing.
Robert Morse, Adrian G Todd, Philip J Young

Methods Mol Biol· July 2012

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Mutations in the survival motor neuron (SMN) protein alter the dynamic nature of nuclear bodies.
Robert Morse, Adrian G Todd, Debra J Shaw, Alison L McConville, Iain M Robinson

Neuromolecular Med· March 2011

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SMN, Gemin2 and Gemin3 associate with beta-actin mRNA in the cytoplasm of neuronal cells in vitro.
Adrian G Todd, Robert Morse, Debra J Shaw, Samuel McGinley, Howard Stebbings

J Mol Biol· September 2010

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Analysis of SMN-neurite granules: Core Cajal body components are absent from SMN-cytoplasmic complexes.
Adrian G Todd, Robert Morse, Debra J Shaw, Howard Stebbings, Philip J Young

Biochem Biophys Res Commun· July 2010

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Identification of a self-association domain in the Ewing's sarcoma protein: a novel function for arginine-glycine-glycine rich motifs?
Debra J Shaw, Robert Morse, Adrian G Todd, Paul Eggleton, Christian L Lorson

J Biochem· June 2010

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SMN and the Gemin proteins form sub-complexes that localise to both stationary and dynamic neurite granules.
Adrian G Todd, Debra J Shaw, Robert Morse, Howard Stebbings, Philip J Young

Biochem Biophys Res Commun· March 2010

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Identification of a tripartite import signal in the Ewing Sarcoma protein (EWS).
Debra J Shaw, Robert Morse, Adrian G Todd, Paul Eggleton, Christian L Lorson

Biochem Biophys Res Commun· December 2009

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Identification and characterisation of a nuclear localisation signal in the SMN associated protein, Gemin4.
Monique A Lorson, Alexa M Dickson, Debra J Shaw, Adrian G Todd, Elizabeth C Young

Biochem Biophys Res Commun· October 2008

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Targeting of SMN to Cajal bodies is mediated by self-association.
Robert Morse, Debra J Shaw, Adrian G Todd, Philip J Young

Hum Mol Genet· October 2007

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3rd UK Spinal Muscular Atrophy (SMA) Researchers Network Meeting.
Debra J Shaw, Adrian G Todd, Robert Morse, Philip J Young

Neuromuscul Disord· June 2007

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