Publications by authors named "Adrian Gottschlich"

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FLT3-directed BiTE Molecules versus CAR T Cells in AML: Co-stimulatory Signals Mitigate T-Cell Exhaustion.
Lisa Rohrbacher, Daniel Nixdorf, Helena Stadler, Bettina Brauchle, Florian Märkl, Adrian Gottschlich

Blood Adv· December 2025

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Gut Microbiota Modulation through Akkermansia spp. Supplementation Increases CAR T-cell Potency.
Laura Marcos-Kovandzic, Michele Avagliano, Myriam Ben Khelil, Janesa Srikanthan, Rim Abdallah, Adrian Gottschlich

Cancer Discov· September 2025

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Novel approaches to CAR T cell target identification in acute myeloid leukemia.
Gordon Victor Hoffmann, Adrian Gottschlich, Marion Subklewe, Sebastian Kobold

Curr Opin Pharmacol· June 2025

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The role of single cell transcriptomics for efficacy and toxicity profiling of chimeric antigen receptor (CAR) T cell therapies.
Moritz Thomas, Ruben Brabenec, Lisa Gregor, David Andreu-Sanz, Emanuele Carlini, Adrian Gottschlich

Comput Biol Med· June 2025

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Dissection of single-cell landscapes for the development of chimeric antigen receptor T cells in Hodgkin lymphoma.
Adrian Gottschlich, Ruth Grünmeier, Gordon Victor Hoffmann, Sayantan Nandi, Vladyslav Kavaka

Blood· April 2025

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Sex-dependent modulation of T and NK cells and gut microbiome by low sodium diet in patients with primary aldosteronism.
Hanna F Nowotny, Tingting Zheng, Thomas Marchant Seiter, Jing Ju, Holger Schneider, Adrian Gottschlich

Front Immunol· January 2025

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Beyond CAR T cells: exploring alternative cell sources for CAR-like cellular therapies.
Christina Angeliki Tsiverioti, Adrian Gottschlich, Marcel Trefny, Sebastian Theurich, Hans-Joachim Anders

Biol Chem· July 2024

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Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes.
Kami Pekayvaz, Corinna Losert, Viktoria Knottenberg, Christoph Gold, Irene V van Blokland, Adrian Gottschlich

Nat Med· June 2024

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Efficient Chimeric Antigen Receptor T-Cell Generation Starting with Leukoreduction System Chambers of Thrombocyte Apheresis Sets.
Stefani Xhaxho, Linping Chen-Wichmann, Sophie Kreissig, Roland Windisch, Adrian Gottschlich

Transfus Med Hemother· April 2024

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Comparative performance of scFv-based anti-BCMA CAR formats for improved T cell therapy in multiple myeloma.
Sophia Stock, Luisa Fertig, Adrian Gottschlich, Janina Dörr, Florian Märkl

Cancer Immunol Immunother· April 2024

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Major immunophenotypic abnormalities in patients with primary adrenal insufficiency of different etiology.
Hanna F Nowotny, Thomas Marchant Seiter, Jing Ju, Adrian Gottschlich, Holger Schneider

Front Immunol· December 2023

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Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
Adrian Gottschlich, Moritz Thomas, Ruth Grünmeier, Stefanie Lesch, Lisa Rohrbacher

Nat Biotechnol· November 2023

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Programmable multispecific DNA-origami-based T-cell engagers.
Klaus F Wagenbauer, Nhi Pham, Adrian Gottschlich, Benjamin Kick, Viktorija Kozina

Nat Nanotechnol· November 2023

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Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma.
Florian Märkl, Mohamed-Reda Benmebarek, Julius Keyl, Bruno L Cadilha, Martina Geiger, Adrian Gottschlich

J Immunother Cancer· May 2023

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T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.
Daria Briukhovetska, Javier Suarez-Gosalvez, Cornelia Voigt, Anamarija Markota, Anastasios D Giannou, Adrian Gottschlich

Immunity· January 2023

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Impact of the selective A2R and A2R dual antagonist AB928/etrumadenant on CAR T cell function.
Matthias Seifert, Mohamed-Reda Benmebarek, Daria Briukhovetska, Florian Märkl, Janina Dörr, Adrian Gottschlich

Br J Cancer· December 2022

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Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
Uta M Demel, Marlitt Böger, Schayan Yousefian, Corinna Grunert, Le Zhang, Adrian Gottschlich

J Clin Invest· May 2022

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The Neurokinin-1 Receptor Is a Target in Pediatric Rhabdoid Tumors.
Julian Kolorz, Salih Demir, Adrian Gottschlich, Iris Beirith, Matthias Ilmer

Curr Oncol· December 2021

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T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
Stefanie Lesch, Viktoria Blumenberg, Stefan Stoiber, Adrian Gottschlich, Justyna Ogonek

Nat Biomed Eng· November 2021

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A modular and controllable T cell therapy platform for acute myeloid leukemia.
Mohamed-Reda Benmebarek, Bruno L Cadilha, Monika Herrmann, Stefanie Lesch, Saskia Schmitt, Adrian Gottschlich

Leukemia· August 2021

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Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors.
Bruno L Cadilha, Mohamed-Reda Benmebarek, Klara Dorman, Arman Oner, Theo Lorenzini, Adrian Gottschlich

Sci Adv· June 2021

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CAR T cell therapy in solid tumors: a short review.
Öykü Umut, Adrian Gottschlich, Stefan Endres, Sebastian Kobold

Memo· April 2021

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Therapeutic Strategies for Targeting IL-1 in Cancer.
Adrian Gottschlich, Stefan Endres, Sebastian Kobold

Cancers (Basel)· January 2021

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Interleukin-37 monomer is the active form for reducing innate immunity.
Elan Z Eisenmesser, Adrian Gottschlich, Jasmina S Redzic, Natasia Paukovich, Jay C Nix

Proc Natl Acad Sci U S A· March 2019

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Can we use interleukin-1β blockade for lung cancer treatment?
Adrian Gottschlich, Stefan Endres, Sebastian Kobold

Transl Lung Cancer Res· April 2018

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