Publications by authors named "Adrian Handforth"

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A Role for GABA Receptor β3 Subunits in Mediating Harmaline Tremor Suppression by Alcohol: Implications for Essential Tremor Therapy.
Adrian Handforth, Ram P Singh, Hovsep P Kosoyan, Pournima A Kadam

Tremor Other Hyperkinet Mov (N Y)· April 2024

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Search for Novel Therapies for Essential Tremor Based on Positive Modulation of α6-Containing GABA Receptors.
Adrian Handforth, Ram P Singh, Marco Treven, Margot Ernst

Tremor Other Hyperkinet Mov (N Y)· October 2023

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Alcohol and Ganaxolone Suppress Tremor via Extra-Synaptic GABA Receptors in the Harmaline Model of Essential Tremor.
Adrian Handforth, Hovsep P Kosoyan, Pournima A Kadam, Ram P Singh

Tremor Other Hyperkinet Mov (N Y)· May 2023

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Is the inferior olive central to essential tremor? Yes.
Eric J Lang, Adrian Handforth

Int Rev Neurobiol· June 2022

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A Phase 2 Proof-of-Concept, Randomized, Placebo-Controlled Trial of CX-8998 in Essential Tremor.
Spyros Papapetropoulos, Margaret S Lee, Stacey Versavel, Evan Newbold, Hyder A Jinnah, Adrian Handforth

Mov Disord· August 2021

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Increased Purkinje Cell Complex Spike and Deep Cerebellar Nucleus Synchrony as a Potential Basis for Syndromic Essential Tremor. A Review and Synthesis of the Literature.
Adrian Handforth, Eric J Lang

Cerebellum· April 2021

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A Pilot Double-Blind Randomized Trial of Perampanel for Essential Tremor.
Adrian Handforth, Winona Tse, Rodger J Elble

Mov Disord Clin Pract· May 2020

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Current Opinions and Consensus for Studying Tremor in Animal Models.
Sheng-Han Kuo, Elan D Louis, Phyllis L Faust, Adrian Handforth, Su-Youne Chang

Cerebellum· December 2019

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Conditions Associated with Essential Tremor in Veterans: A Potential Role for Chronic Stress.
Adrian Handforth, Gail A Parker

Tremor Other Hyperkinet Mov (N Y)· November 2018

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Suppression of Harmaline Tremor by Activation of an Extrasynaptic GABA Receptor: Implications for Essential Tremor.
Adrian Handforth, Pournima A Kadam, Hovsep P Kosoyan, Pirooz Eslami

Tremor Other Hyperkinet Mov (N Y)· November 2018

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Linking Essential Tremor to the Cerebellum-Animal Model Evidence.
Adrian Handforth

Cerebellum· June 2016

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Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy.
Vicenta Salanova, Thomas Witt, Robert Worth, Thomas R Henry, Robert E Gross, Adrian Handforth

Neurology· March 2015

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Harmaline tremor: underlying mechanisms in a potential animal model of essential tremor.
Adrian Handforth

Tremor Other Hyperkinet Mov (N Y)· July 2013

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Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor.
Fatta B Nahab, Adrian Handforth, Tyler Brown, Christopher Shin, Arnulfo Quesada

Neurotherapeutics· July 2012

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Comparison of mibefradil and derivative NNC 55-0396 effects on behavior, cytochrome P450 activity, and tremor in mouse models of essential tremor.
Arnulfo Quesada, Peter H Bui, Gregg E Homanics, Oliver Hankinson, Adrian Handforth

Eur J Pharmacol· May 2011

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C-terminal mechano-growth factor induces heme oxygenase-1-mediated neuroprotection of SH-SY5Y cells via the protein kinase Cϵ/Nrf2 pathway.
Arnulfo Quesada, Julie Ogi, James Schultz, Adrian Handforth

J Neurosci Res· March 2011

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A pilot efficacy and tolerability trial of memantine for essential tremor.
Adrian Handforth, Yvette Bordelon, Steven J Frucht, Arnulfo Quesada

Clin Neuropharmacol· January 2011

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T-type calcium channel antagonists suppress tremor in two mouse models of essential tremor.
Adrian Handforth, Gregg E Homanics, Douglas F Covey, Kathiresan Krishnan, Jae Yeol Lee

Neuropharmacology· November 2010

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Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy.
Robert Fisher, Vicenta Salanova, Thomas Witt, Robert Worth, Thomas Henry, Adrian Handforth

Epilepsia· May 2010

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C-terminal mechano growth factor protects dopamine neurons: a novel peptide that induces heme oxygenase-1.
Arnulfo Quesada, Paul Micevych, Adrian Handforth

Exp Neurol· December 2009

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Zonisamide for essential tremor: an evaluator-blinded study.
Adrian Handforth, Fredricka C Martin, Gail A Kang, Zeba Vanek

Mov Disord· February 2009

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The mibefradil derivative NNC55-0396, a specific T-type calcium channel antagonist, exhibits less CYP3A4 inhibition than mibefradil.
Peter H Bui, Arnulfo Quesada, Adrian Handforth, Oliver Hankinson

Drug Metab Dispos· July 2008

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Carbenoxolone and mefloquine suppress tremor in the harmaline mouse model of essential tremor.
Fredricka C Martin, Adrian Handforth

Mov Disord· October 2006

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Deep brain stimulation of the subthalamic nucleus as adjunct treatment for refractory epilepsy.
Adrian Handforth, Antonio A F DeSalles, Scott E Krahl

Epilepsia· July 2006

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Pharmacologic evidence for abnormal thalamocortical functioning in GABA receptor beta3 subunit-deficient mice, a model of Angelman syndrome.
Adrian Handforth, Timothy M Delorey, Gregg E Homanics, Richard W Olsen

Epilepsia· December 2005

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