Publications by authors named "Adrian J Lapthorn"

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Human mitochondrial glutathione transferases: Kinetic parameters and accommodation of a mitochondria-targeting group in substrates.
Patrick A Cardwell, Carlo Del Moro, Michael P Murphy, Adrian J Lapthorn, Richard C Hartley

Bioorg Med Chem· April 2024

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Multiplexed Biosensing of Proteins and Virions with Disposable Plasmonic Assays.
Stephanie Wallace, Martin Kartau, Tarun Kakkar, Chris Davis, Agnieszka Szemiel, Adrian J Lapthorn

ACS Sens· September 2023

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Superchiral near fields detect virus structure.
Tarun Kakkar, Chantal Keijzer, Marion Rodier, Tatyana Bukharova, Michael Taliansky, Adrian J Lapthorn

Light Sci Appl· December 2020

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Probing Specificity of Protein-Protein Interactions with Chiral Plasmonic Nanostructures.
Marion Rodier, Chantal Keijzer, Joel Milner, Affar S Karimullah, Laurence D Barron, Adrian J Lapthorn

J Phys Chem Lett· October 2019

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Chiral Plasmonic Fields Probe Structural Order of Biointerfaces.
Christopher Kelly, Ryan Tullius, Adrian J Lapthorn, Nikolaj Gadegaard, Graeme Cooke

J Am Chem Soc· July 2018

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Superchiral Plasmonic Phase Sensitivity for Fingerprinting of Protein Interface Structure.
Ryan Tullius, Geoffrey W Platt, Larousse Khosravi Khorashad, Nikolaj Gadegaard, Adrian J Lapthorn

ACS Nano· December 2017

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Pharmacophore searching: A potential solution for correcting unknown ligands (UNK) labelling errors in Protein Data Bank (PDB'S).
Musadiq Ibrahim, Adrian Jonathan Lapthorn, Mohammad Ibrahim

J Mol Graph Model· August 2017

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Spectrum of Slow and Super-Slow (Picosecond to Nanosecond) Water Dynamics around Organic and Biological Solutes.
Gopakumar Ramakrishnan, Mario González-Jiménez, Adrian J Lapthorn, Klaas Wynne

J Phys Chem Lett· July 2017

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Standardization of Epitopes for Human Chorionic Gonadotropin (hCG) Immunoassays.
Peter Berger, Adrian J Lapthorn

Curr Med Chem· February 2017

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The molecular relationship between antigenic domains and epitopes on hCG.
Peter Berger, Adrian J Lapthorn

Mol Immunol· August 2016

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Observation of coherent delocalized phonon-like modes in DNA under physiological conditions.
Mario González-Jiménez, Gopakumar Ramakrishnan, Thomas Harwood, Adrian J Lapthorn, Sharon M Kelly

Nat Commun· June 2016

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Spatial control of chemical processes on nanostructures through nano-localized water heating.
Calum Jack, Affar S Karimullah, Ryan Tullius, Larousse Khosravi Khorashad, Marion Rodier, Adrian J Lapthorn

Nat Commun· March 2016

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Terahertz underdamped vibrational motion governs protein-ligand binding in solution.
David A Turton, Hans Martin Senn, Thomas Harwood, Adrian J Lapthorn, Elizabeth M Ellis

Nat Commun· June 2014

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The diversity of microbial aldo/keto reductases from Escherichia coli K12.
Adrian J Lapthorn, Xiaofeng Zhu, Elizabeth M Ellis

Chem Biol Interact· February 2013

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Synthesis and evaluation of potent ene-yne inhibitors of type II dehydroquinases as tuberculosis drug leads.
Anh Thu Tran, Katie M Cergol, Nicholas P West, Elizabeth J Randall, Warwick J Britton, Adrian J Lapthorn

ChemMedChem· February 2011

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Tetrahydrobenzothiophene derivatives: conformationally restricted inhibitors of type II dehydroquinase.
Sonia Paz, Lorena Tizón, José M Otero, Antonio L Llamas-Saiz, Gavin C Fox, Adrian J Lapthorn

ChemMedChem· February 2011

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Type II dehydroquinase: molecular replacement with many copies.
Kirsty Anne Stewart, David Alexander Robinson, Adrian Jonathan Lapthorn

Acta Crystallogr D Biol Crystallogr· January 2008

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Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinases.
Richard J Payne, Alan Riboldi-Tunnicliffe, Olivier Kerbarh, Andrew D Abell, Adrian J Lapthorn

ChemMedChem· July 2007

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Nanomolar competitive inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor type II dehydroquinase.
Verónica F V Prazeres, Cristina Sánchez-Sixto, Luis Castedo, Heather Lamb, Alastair R Hawkins, Adrian J Lapthorn

ChemMedChem· February 2007

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Application of a new vector system for efficient protein purification in the crystallization of PA5104/ORF from Pseudomonas aeruginosa.
Bernhard Lohkamp, Neil G Paterson, Adrian J Lapthorn

J Struct Biol· July 2006

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Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity.
Xiaofeng Zhu, Adrian J Lapthorn, Elizabeth M Ellis

Biochemistry· February 2006

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Crystal structures of Helicobacter pylori type II dehydroquinase inhibitor complexes: new directions for inhibitor design.
David A Robinson, Kirsty A Stewart, Nicholas C Price, Peter A Chalk, John R Coggins, Adrian J Lapthorn

J Med Chem· February 2006

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Rational design of new bifunctional inhibitors of type II dehydroquinase.
Miguel D Toscano, Kirsty A Stewart, John R Coggins, Adrian J Lapthorn, Chris Abell

Org Biomol Chem· September 2005

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(1R,4S,5R)-3-Fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid: the fluoro analogue of the enolate intermediate in the reaction catalyzed by type II dehydroquinases.
Martyn Frederickson, Aleksander W Roszak, John R Coggins, Adrian J Lapthorn, Chris Abell

Org Biomol Chem· June 2004

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The structure of Escherichia coli ATP-phosphoribosyltransferase: identification of substrate binding sites and mode of AMP inhibition.
Bernhard Lohkamp, Gerry McDermott, Samantha A Campbell, John R Coggins, Adrian J Lapthorn

J Mol Biol· February 2004

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