Publications by authors named "Adrian J Lloyd"

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Transcriptomic and enzymological evidence for plastid peptidoglycan synthesis in the gymnosperm Picea abies.
Yayoi Sugita, Amanda J Dowson, Ichiro Kajisa, Katsuaki Takechi, Yilan E, Adrian J Lloyd

Plant J· December 2025

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Discovery and chemical optimisation of a potent, Bi-cyclic antimicrobial inhibitor of Escherichia coli PBP3.
Catherine E Rowland, Hector Newman, Tazmin T Martin, Rachel Dods, Nikolaos Bournakas, Adrian J Lloyd

Commun Biol· May 2025

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Factors that influence psychiatric trainees' choice of higher training specialty: mixed-methods study.
Nicholas Wolstenholme, Iain McKinnon, Adrian J Lloyd

BJPsych Bull· June 2023

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A quantitative analysis of the relationship between affective state and personality ratings in inpatient depression (RAPID).
Kaushadh Jayakody, Peter Gallagher, Adrian J Lloyd, David Andrew Cousins

Psychol Med· June 2023

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A conserved zinc-binding site in PBP2 required for elongasome-directed bacterial cell shape.
Carmina Micelli, Yunfei Dai, Nicole Raustad, Ralph R Isberg, Christopher G Dowson, Adrian J Lloyd

Proc Natl Acad Sci U S A· February 2023

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Plant peptidoglycan precursor biosynthesis: Conservation between moss chloroplasts and Gram-negative bacteria.
Amanda J Dowson, Adrian J Lloyd, Andrew C Cuming, David I Roper, Lorenzo Frigerio

Plant Physiol· August 2022

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Structure-based modeling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant present at the cytoplasmic membrane.
Anna York, Adrian J Lloyd, Charo I Del Genio, Jonathan Shearer, Karen J Hinxman

Structure· July 2021

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A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in .
Surya D Aggarwal, Adrian J Lloyd, Saigopalakrishna S Yerneni, Ana Rita Narciso, Jennifer Shepherd

Proc Natl Acad Sci U S A· April 2021

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Substrate and Stereochemical Control of Peptidoglycan Cross-Linking by Transpeptidation by PBP1B.
Anita C Catherwood, Adrian J Lloyd, Julie A Tod, Smita Chauhan, Susan E Slade

J Am Chem Soc· March 2020

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Structure-Guided Enhancement of Selectivity of Chemical Probe Inhibitors Targeting Bacterial Seryl-tRNA Synthetase.
Ricky Cain, Ramya Salimraj, Avinash S Punekar, Dom Bellini, Colin W G Fishwick, Lloyd Czaplewski, Adrian J Lloyd

J Med Chem· November 2019

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Structural studies suggest aggregation as one of the modes of action for teixobactin.
Carl Öster, Grzegorz P Walkowiak, Dallas E Hughes, Amy L Spoering, Aaron J Peoples, Adrian J Lloyd

Chem Sci· December 2018

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The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization.
Avinash S Punekar, Firdaus Samsudin, Adrian J Lloyd, Christopher G Dowson, David J Scott

Cell Surf· June 2018

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Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine.
Sarah Batson, Cesira de Chiara, Vita Majce, Adrian J Lloyd, Stanislav Gobec

Nat Commun· December 2017

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Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase.
Veeraraghavan Usha, Adrian J Lloyd, David I Roper, Christopher G Dowson, Guennadi Kozlov

Sci Rep· March 2016

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Antidepressant augmentation with metyrapone for treatment-resistant depression (the ADD study): a double-blind, randomised, placebo-controlled trial.
R Hamish McAllister-Williams, Ian M Anderson, Andreas Finkelmeyer, Peter Gallagher, Heinz C R Grunze, Adrian J Lloyd

Lancet Psychiatry· February 2016

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Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target.
Sudagar S Gurcha, Veeraraghavan Usha, Jonathan A G Cox, Klaus Fütterer, Katherine A Abrahams, Adrian J Lloyd

PLoS One· December 2015

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Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Johannes Zuegg, Craig Muldoon, George Adamson, Declan McKeveney, Giang Le Thanh, Adrian J Lloyd

Nat Commun· July 2015

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Corpus callosum changes in euthymic bipolar affective disorder.
Adrian J Lloyd, Heba E Ali, David Nesbitt, P Brian Moore, Allan H Young

Br J Psychiatry· February 2014

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Specificity determinants for lysine incorporation in Staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex.
Karen M Ruane, Adrian J Lloyd, Vilmos Fülöp, Christopher G Dowson, Hélène Barreteau

J Biol Chem· November 2013

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Adenosine tetraphosphoadenosine drives a continuous ATP-release assay for aminoacyl-tRNA synthetases and other adenylate-forming enzymes.
Adrian J Lloyd, Nicola J Potter, Colin W G Fishwick, David I Roper, Christopher G Dowson

ACS Chem Biol· October 2013

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Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway.
Karin Valegård, Aman Iqbal, Nadia J Kershaw, David Ivison, Catherine Généreux, Adrian J Lloyd

Acta Crystallogr D Biol Crystallogr· August 2013

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Study protocol for the randomised controlled trial: antiglucocorticoid augmentation of anti-Depressants in Depression (The ADD Study).
R Hamish McAllister-Williams, Eleanor Smith, Ian M Anderson, Jane Barnes, Peter Gallagher, Adrian J Lloyd

BMC Psychiatry· August 2013

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Periventricular white matter integrity and cortisol levels in healthy controls and in euthymic patients with bipolar disorder: an exploratory analysis.
Karine A N Macritchie, Peter Gallagher, Adrian J Lloyd, Mark E Bastin, Kamini Vasudev

J Affect Disord· June 2013

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Structure and function of Mycobacterium tuberculosis meso-diaminopimelic acid (DAP) biosynthetic enzymes.
Veeraraghavan Usha, Adrian J Lloyd, Andrew L Lovering, Gurdyal S Besra

FEMS Microbiol Lett· May 2012

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