Publications by authors named "Adrian Jubb"

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Comparative outcomes of nab-paclitaxel and paclitaxel in platinum-resistant ovarian cancer (COMPASS).
Mark S Shahin, Raina Mathur, Anju Parthan, Prakirthi Yerram, Amanda Kesner-Hays, Adrian M Jubb

Gynecol Oncol· December 2025

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Relacorilant and nab-paclitaxel in patients with platinum-resistant ovarian cancer (ROSELLA): an open-label, randomised, controlled, phase 3 trial.
Alexander B Olawaiye, Laurence Gladieff, David M O'Malley, Jae-Weon Kim, Gabriel Garbaos, Adrian M Jubb

Lancet· June 2025

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Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers.
Daehwan Kim, Heekyung Chung, Wen Liu, Kangjin Jeong, Tugba Y Ozmen, Adrian Jubb

NPJ Precis Oncol· January 2025

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Advancing drug discovery using the power of the human genome.
Karl Heilbron, Sahar V Mozaffari, Vladimir Vacic, Peng Yue, Wei Wang, Adrian M Jubb

J Pathol· July 2021

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Potent LpxC Inhibitors with Activity against Multidrug-Resistant Pseudomonas aeruginosa.
Kevin M Krause, Cat M Haglund, Christy Hebner, Alisa W Serio, Grace Lee, Adrian Jubb

Antimicrob Agents Chemother· November 2019

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Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.
Frederick Cohen, James B Aggen, Logan D Andrews, Zahra Assar, Jen Boggs, Adrian Jubb

ChemMedChem· August 2019

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Plazomicin for Infections Caused by Carbapenem-Resistant Enterobacteriaceae.
James A McKinnell, Jamie P Dwyer, George H Talbot, Lynn E Connolly, Ian Friedland, Adrian M Jubb

N Engl J Med· February 2019

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Hypoxia-related biological markers as predictors of epirubicin-based treatment responsiveness and resistance in locally advanced breast cancer.
Manuela Milani, Sergio Venturini, Simone Bonardi, Giovanni Allevi, Carla Strina, Adrian Jubb

Oncotarget· October 2017

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Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth.
Chern Ein Oon, Esther Bridges, Helen Sheldon, Richard C A Sainson, Adrian Jubb

Oncotarget· June 2017

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Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment.
Shaveta Mehta, Nick P Hughes, Sonia Li, Adrian Jubb, Rosie Adams

EBioMedicine· August 2016

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MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation.
Tom T Chen, Ellen Filvaroff, Jing Peng, Scot Marsters, Adrian Jubb

EBioMedicine· May 2015

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Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.
Christy C Ong, Sarah Gierke, Cameron Pitt, Meredith Sagolla, Christine K Cheng, Adrian M Jubb

Breast Cancer Res· April 2015

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Effect of selective LRRK2 kinase inhibition on nonhuman primate lung.
Reina N Fuji, Michael Flagella, Miriam Baca, Marco A S Baptista, Jens Brodbeck, Adrian M Jubb

Sci Transl Med· February 2015

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PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition.
Wei Zhou, Adrian M Jubb, Karen Lyle, Qian Xiao, Christy C Ong

J Pathol· December 2014

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A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models.
Dara Y Kallop, William J Meilandt, Alvin Gogineni, Courtney Easley-Neal, Tiffany Wu, Adrian M Jubb

J Neurosci· May 2014

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DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.
Tammie S MacFie, Richard Poulsom, Alexandra Parker, Gary Warnes, Tatjana Boitsova, Adrian M Jubb

Inflamm Bowel Dis· March 2014

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Lymph node-independent liver metastasis in a model of metastatic colorectal cancer.
Ida B Enquist, Zinaida Good, Adrian M Jubb, Germaine Fuh, Xi Wang

Nat Commun· March 2014

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Pathology in drug discovery and development.
Adrian M Jubb, Hartmut Koeppen, Jorge S Reis-Filho

J Pathol· January 2014

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Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
Christine D Pozniak, Arundhati Sengupta Ghosh, Alvin Gogineni, Jesse E Hanson, Seung-Hye Lee, Adrian M Jubb

J Exp Med· November 2013

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Impact of MET expression on outcome in BRAF(V600E/K) advanced melanoma.
Adrian M Jubb, Antoni Ribas, Jeffrey A Sosman, Grant A McArthur, Yibing Yan

Histopathology· September 2013

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Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy.
Leisa Johnson, Mahrukh Huseni, Tanya Smyczek, Anthony Lima, Stacey Yeung, Adrian M Jubb

J Clin Invest· September 2013

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High heregulin expression is associated with activated HER3 and may define an actionable biomarker in patients with squamous cell carcinomas of the head and neck.
David S Shames, Juliet Carbon, Kim Walter, Adrian M Jubb, Cleopatra Kozlowski

PLoS One· August 2013

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Identification and analysis of in vivo VEGF downstream markers link VEGF pathway activity with efficacy of anti-VEGF therapies.
Matthew J Brauer, Guanglei Zhuang, Maike Schmidt, Jenny Yao, Xiumin Wu, Adrian Jubb

Clin Cancer Res· July 2013

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P21-activated kinase 1 (PAK1) as a therapeutic target in BRAF wild-type melanoma.
Christy C Ong, Adrian M Jubb, Diana Jakubiak, Wei Zhou, Joachim Rudolph

J Natl Cancer Inst· May 2013

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Predictive impact of circulating vascular endothelial growth factor in four phase III trials evaluating bevacizumab.
Priti S Hegde, Adrian M Jubb, Dafeng Chen, Nicole F Li, Y Gloria Meng

Clin Cancer Res· February 2013

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