Publications by authors named "Adrian Serone"

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Discovery of Edecesertib (GS-5718): A Potent, Selective Inhibitor of IRAK4.
Stephen E Ammann, Jeromy J Cottell, Nathan E Wright, Matthew R Warr, Chelsea A Snyder, Adrian P Serone

J Med Chem· June 2025

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Efficacy and Safety of Filgotinib for the Treatment of Perianal Fistulising Crohn's Disease [DIVERGENCE 2]: A Phase 2, Randomised, Placebo-controlled Trial.
Walter Reinisch, Jean-Frederic Colombel, Geert R D'Haens, Jordi Rimola, Tomasz Masior, Adrian Serone

J Crohns Colitis· June 2024

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Filgotinib for the Treatment of Small Bowel Crohn's Disease: The DIVERGENCE 1 Trial.
Geert R D'Haens, Scott Lee, Stuart A Taylor, Adrian Serone, Jordi Rimola

Gastroenterology· July 2023

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Mucosal p-STAT1/3 correlates with histologic disease activity in Crohn's disease and is responsive to filgotinib.
Walter Reinisch, Adrian Serone, Xavier Hébuterne, Tanja Kühbacher, Maria Kłopocka

Tissue Barriers· April 2023

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Effects of JAK1-Preferential Inhibitor Filgotinib on Circulating Biomarkers and Whole Blood Genes/Pathways of Patients With Moderately to Severely Active Crohn's Disease.
Xavier Roblin, Adrian Serone, Oh Kyu Yoon, Luting Zhuo, Ethan Grant

Inflamm Bowel Dis· August 2022

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Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury.
Alastair Proudfoot, Andrew Bayliffe, Cecilia M O'Kane, Tracey Wright, Adrian Serone

Thorax· August 2018

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Safety, Pharmacokinetics, and Pharmacodynamics in Healthy Volunteers Treated With GDC-0853, a Selective Reversible Bruton's Tyrosine Kinase Inhibitor.
Ann E Herman, Leslie W Chinn, Shweta G Kotwal, Elaine R Murray, Rui Zhao, Adrian P Serone

Clin Pharmacol Ther· June 2018

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Efficacy and safety of an anti-IL-13 mAb in patients with severe asthma: a randomized trial.
Erika H De Boever, Claire Ashman, Anthony P Cahn, Nicholas W Locantore, Phil Overend, Adrian P Serone

J Allergy Clin Immunol· April 2014

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A phase 1, randomized, placebo-controlled, dose-escalation study of an anti-IL-13 monoclonal antibody in healthy subjects and mild asthmatics.
Peter Hodsman, Claire Ashman, Anthony Cahn, Erika De Boever, Nicholas Locantore, Adrian Serone

Br J Clin Pharmacol· January 2013

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High-density lipoprotein (HDL) transport in the metabolic syndrome: application of a new model for HDL particle kinetics.
Juying Ji, Gerald F Watts, Anthony G Johnson, Dick C Chan, Esther M M Ooi, Adrian P Serone

J Clin Endocrinol Metab· March 2006

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Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome.
Gerald F Watts, P Hugh R Barrett, Juying Ji, Adrian P Serone, Dick C Chan

Diabetes· March 2003

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The effect of an HIV-1 viral protease inhibitor on staurosporine-induced apoptosis in immortalized mesangial cells.
Adrian Pierce Serone, Simone Mafalda Rodrigues Camargo, Nestor Schor

Sao Paulo Med J· May 2002

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