Publications by authors named "Adrian Timmers"

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AAV Gene Augmentation of Truncated Complement Factor H Differentially Rescues Ocular Complement Dysregulation in a Mouse Model.
Daniel Grigsby, Mikael Klingeborn, Una Kelly, Lindsey A Chew, Aravind Asokan, Adrian Timmers

Invest Ophthalmol Vis Sci· July 2023

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Dose Range Finding Studies with Two Transgenes in a Canine Model of X-Linked Retinitis Pigmentosa Treated with Subretinal Gene Therapy.
Chunjuan Song, Valérie L Dufour, Artur V Cideciyan, Guo-Jie Ye, Malgorzata Swider, Adrian M Timmers

Hum Gene Ther· July 2020

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Toxicity and Efficacy Evaluation of an Adeno-Associated Virus Vector Expressing Codon-Optimized Delivered by Subretinal Injection in a Canine Model of X-linked Retinitis Pigmentosa.
Valérie L Dufour, Artur V Cideciyan, Guo-Jie Ye, Chunjuan Song, Adrian Timmers

Hum Gene Ther· February 2020

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Ocular Inflammatory Response to Intravitreal Injection of Adeno-Associated Virus Vector: Relative Contribution of Genome and Capsid.
Adrian M Timmers, Judith A Newmark, Heikki T Turunen, Tanaz Farivar, Jilin Liu

Hum Gene Ther· January 2020

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Toxicology and Pharmacology of an AAV Vector Expressing Codon-Optimized RPGR in RPGR-Deficient Rd9 Mice.
Chunjuan Song, Thomas J Conlon, Wen-Tao Deng, Kirsten E Coleman, Ping Zhu, Adrian Timmers

Hum Gene Ther Clin Dev· December 2018

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Characterization of intraocular immunopathology following intracameral inoculation with alloantigen.
Daniel R Saban, Ian A Elder, Cuong Q Nguyen, W Clay Smith, Adrian M Timmers

Mol Vis· March 2008

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Cone-specific expression using a human red opsin promoter in recombinant AAV.
Qiuhong Li, Adrian M Timmers, John Guy, Jijing Pang, William W Hauswirth

Vision Res· February 2008

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Restoration of cone vision in a mouse model of achromatopsia.
John J Alexander, Yumiko Umino, Drew Everhart, Bo Chang, Seok H Min, Adrian M Timmers

Nat Med· June 2007

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Disease mechanisms and gene therapy in a mouse model for X-linked retinoschisis.
Laurie L Molday, Seok-Hong Min, Mathias W Seeliger, Winco W H Wu, Astra Dinculescu, Adrian M Timmers

Adv Exp Med Biol· April 2007

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Development of a microarray chip for gene expression in rabbit ocular research.
Michael P Popp, Li Liu, Adrian Timmers, Douglas W Esson, Lineu Shiroma

Mol Vis· February 2007

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Human blue-opsin promoter preferentially targets reporter gene expression to rat s-cone photoreceptors.
Lyudmyla G Glushakova, Adrian M Timmers, Jijing Pang, Jacqueline T Teusner, William W Hauswirth

Invest Ophthalmol Vis Sci· August 2006

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Does recombinant adeno-associated virus-vectored proximal region of mouse rhodopsin promoter support only rod-type specific expression in vivo?
Lyudmyla G Glushakova, Adrian M Timmers, Tawfik M Issa, Nenita G Cortez, Jijing Pang

Mol Vis· April 2006

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Prolonged recovery of retinal structure/function after gene therapy in an Rs1h-deficient mouse model of x-linked juvenile retinoschisis.
Seok H Min, Laurie L Molday, Mathias W Seeliger, Astra Dinculescu, Adrian M Timmers

Mol Ther· October 2005

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Ribozyme knockdown of the gamma-subunit of rod cGMP phosphodiesterase alters the ERG and retinal morphology in wild-type mice.
Jianwen Liu, Adrian M Timmers, Alfred S Lewin, William W Hauswirth

Invest Ophthalmol Vis Sci· October 2005

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Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors.
Nilanjana Sengupta, Sergio Caballero, Robert N Mames, Adrian M Timmers, Daniel Saban

Invest Ophthalmol Vis Sci· January 2005

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AAV-mediated intravitreal gene therapy reduces lysosomal storage in the retinal pigmented epithelium and improves retinal function in adult MPS VII mice.
Anne K Hennig, Judith Mosinger Ogilvie, Kevin K Ohlemiller, Adrian M Timmers, William W Hauswirth

Mol Ther· July 2004

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Range of retinal diseases potentially treatable by AAV-vectored gene therapy.
William W Hauswirth, Quihong Li, Brian Raisler, Adrian M Timmers, Kenneth I Berns

Novartis Found Symp· March 2004

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A muscleblind knockout model for myotonic dystrophy.
Rahul N Kanadia, Karen A Johnstone, Ami Mankodi, Codrin Lungu, Charles A Thornton, Adrian M Timmers

Science· December 2003

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Anti-apoptotic effects of CNTF gene transfer on photoreceptor degeneration in experimental antibody-induced retinopathy.
Grazyna Adamus, Brad Sugden, Sharon Shiraga, Adrian M Timmers, William W Hauswirth

J Autoimmun· September 2003

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Decreased expression of the insulin-like growth factor 1 receptor by ribozyme cleavage.
Lynn C Shaw, Aqeela Afzal, Alfred S Lewin, Adrian M Timmers, Polyxenie E Spoerri

Invest Ophthalmol Vis Sci· September 2003

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Structural and functional protection of photoreceptors from MNU-induced retinal degeneration by the X-linked inhibitor of apoptosis.
Dino Petrin, Adam Baker, Stuart G Coupland, Peter Liston, Monica Narang, Adrian Timmers

Invest Ophthalmol Vis Sci· June 2003

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Inactivation of the Basigin gene impairs normal retinal development and maturation.
Judith D Ochrietor, Tatiana P Moroz, Michael F Clamp, Adrian M Timmers, Takashi Muramatsu

Vision Res· February 2002

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