Publications by authors named "Adrish Sen"

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Functional Analysis of the PI3K/AKT/mTOR Pathway Inhibitor, Gedatolisib, Plus Fulvestrant with and Without Palbociclib in Breast Cancer Models.
Aaron Broege, Stefano Rossetti, Adrish Sen, Ann De La Forest, Laura Davis

Int J Mol Sci· June 2025

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Assessments of prostate cancer cell functions highlight differences between a pan-PI3K/mTOR inhibitor, gedatolisib, and single-node inhibitors of the PI3K/AKT/mTOR pathway.
Adrish Sen, Salmaan Khan, Stefano Rossetti, Aaron Broege, Ian MacNeil

Mol Oncol· January 2025

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Functional Assessments of Gynecologic Cancer Models Highlight Differences Between Single-Node Inhibitors of the PI3K/AKT/mTOR Pathway and a Pan-PI3K/mTOR Inhibitor, Gedatolisib.
Aaron Broege, Stefano Rossetti, Adrish Sen, Arul S Menon, Ian MacNeil

Cancers (Basel)· October 2024

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Gedatolisib shows superior potency and efficacy versus single-node PI3K/AKT/mTOR inhibitors in breast cancer models.
Stefano Rossetti, Aaron Broege, Adrish Sen, Salmaan Khan, Ian MacNeil

NPJ Breast Cancer· June 2024

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The Role of Vitamin C: From Prevention of Pneumonia to Treatment of Covid-19.
Komal, Jagdeep Kumar, Adrish Sen

Mater Today Proc· November 2022

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Functional signaling test identifies HER2 negative breast cancer patients who may benefit from c-Met and pan-HER combination therapy.
Ian A MacNeil, Salmaan A Khan, Adrish Sen, Sajjad M Soltani, David J Burns

Cell Commun Signal· January 2022

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Rotavirus Reprograms Multiple Interferon Receptors and Restricts Their Intestinal Antiviral and Inflammatory Functions.
Adrish Sen, Nima D Namsa, Ningguo Feng, Harry B Greenberg

J Virol· February 2020

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Rotavirus Degrades Multiple Interferon (IFN) Type Receptors To Inhibit IFN Signaling and Protects against Mortality from Endotoxin in Suckling Mice.
Adrish Sen, Ayushi Sharma, Harry B Greenberg

J Virol· January 2018

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VP4- and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans.
Nitya Nair, Ningguo Feng, Lisa K Blum, Mrinmoy Sanyal, Siyuan Ding, Adrish Sen

Sci Transl Med· June 2017

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Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex.
Siyuan Ding, Nancie Mooney, Bin Li, Marcus R Kelly, Ningguo Feng, Adrish Sen

PLoS Pathog· October 2016

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Correction: Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections.
Jian-Da Lin, Ningguo Feng, Adrish Sen, Murugabaskar Balan, Hsiang-Chi Tseng

PLoS Pathog· June 2016

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Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections.
Jian-Da Lin, Ningguo Feng, Adrish Sen, Murugabaskar Balan, Hsiang-Chi Tseng

PLoS Pathog· April 2016

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Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus.
Nandini Sen, Gourab Mukherjee, Adrish Sen, Sean C Bendall, Phillip Sung

Cell Rep· July 2014

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Rotavirus NSP1 protein inhibits interferon-mediated STAT1 activation.
Adrish Sen, Lusijah Rott, Nguyen Phan, Gourab Mukherjee, Harry B Greenberg

J Virol· January 2014

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Permissive replication of homologous murine rotavirus in the mouse intestine is primarily regulated by VP4 and NSP1.
Ningguo Feng, Linda L Yasukawa, Adrish Sen, Harry B Greenberg

J Virol· August 2013

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The battle between rotavirus and its host for control of the interferon signaling pathway.
Michelle M Arnold, Adrish Sen, Harry B Greenberg, John T Patton

PLoS Pathog· January 2013

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Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution.
Adrish Sen, Michael E Rothenberg, Gourab Mukherjee, Ningguo Feng, Tomer Kalisky

Proc Natl Acad Sci U S A· December 2012

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Human rotavirus-specific IgM Memory B cells have differential cloning efficiencies and switch capacities and play a role in antiviral immunity in vivo.
Carlos F Narváez, Ningguo Feng, Camilo Vásquez, Adrish Sen, Juana Angel

J Virol· October 2012

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The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3.
Adrish Sen, Andrea J Pruijssers, Terence S Dermody, Adolfo García-Sastre, Harry B Greenberg

J Virol· April 2011

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Roles of VP4 and NSP1 in determining the distinctive replication capacities of simian rotavirus RRV and bovine rotavirus UK in the mouse biliary tract.
Ningguo Feng, Adrish Sen, Marie Wolf, Phuoc Vo, Yasutaka Hoshino

J Virol· March 2011

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IRF3 inhibition by rotavirus NSP1 is host cell and virus strain dependent but independent of NSP1 proteasomal degradation.
Adrish Sen, Ningguo Feng, Khalil Ettayebi, Michele E Hardy, Harry B Greenberg

J Virol· October 2009

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The formation of viroplasm-like structures by the rotavirus NSP5 protein is calcium regulated and directed by a C-terminal helical domain.
Adrish Sen, Nandini Sen, Erich R Mackow

J Virol· November 2007

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Degrons at the C terminus of the pathogenic but not the nonpathogenic hantavirus G1 tail direct proteasomal degradation.
Nandini Sen, Adrish Sen, Erich R Mackow

J Virol· April 2007

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Hyperphosphorylation of the rotavirus NSP5 protein is independent of serine 67, [corrected] NSP2, or [corrected] the intrinsic insolubility of NSP5 is regulated by cellular phosphatases.
Adrish Sen, Darin Agresti, Erich R Mackow

J Virol· February 2006

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Inhibition of hepatitis C virus protein expression by RNA interference.
Adrish Sen, Robert Steele, Asish K Ghosh, Arnab Basu, Ranjit Ray

Virus Res· October 2003

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