Publications by authors named "Agnes Brennan"

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Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1.
Agustin Casimiro-Garcia, Christophe Allais, Agnes Brennan, Chulho Choi, Gabriela Dower

J Med Chem· January 2022

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Modulation of the IL-33/IL-13 Axis in Obesity by IL-13Rα2.
Jennifer Duffen, Melvin Zhang, Katherine Masek-Hammerman, Angela Nunez, Agnes Brennan

J Immunol· February 2018

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Therapeutic activity of an interleukin-4/interleukin-13 dual antagonist on oxazolone-induced colitis in mice.
Marion T Kasaian, Karen M Page, Susan Fish, Agnes Brennan, Timothy A Cook

Immunology· November 2014

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An IL-4/IL-13 dual antagonist reduces lung inflammation, airway hyperresponsiveness, and IgE production in mice.
Marion T Kasaian, Kimberly Marquette, Susan Fish, Charlene DeClercq, Rita Agostinelli, Agnes Brennan

Am J Respir Cell Mol Biol· July 2013

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Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCtheta inhibitors.
Diane H Boschelli, Joan Subrath, Chuansheng Niu, Biqi Wu, Yan Wang, Agnes Brennan

Bioorg Med Chem Lett· March 2010

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5-Vinyl-3-pyridinecarbonitrile inhibitors of PKCtheta: optimization of enzymatic and functional activity.
L Nathan Tumey, Niala Bhagirath, Agnes Brennan, Natasja Brooijmans, Julie Lee

Bioorg Med Chem· December 2009

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C-5 substituted heteroaryl-3-pyridinecarbonitriles as PKCtheta inhibitors: part II.
Amar S Prashad, Daniel Wang, Joan Subrath, Biqi Wu, Melissa Lin, Agnes Brennan

Bioorg Med Chem Lett· October 2009

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First generation 5-vinyl-3-pyridinecarbonitrile PKCtheta inhibitors.
Chuansheng Niu, Diane H Boschelli, L Nathan Tumey, Niala Bhagirath, Joan Subrath, Agnes Brennan

Bioorg Med Chem Lett· October 2009

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C-5 Substituted heteroaryl 3-pyridinecarbonitriles as PKCtheta inhibitors: Part I.
Joan Subrath, Daniel Wang, Biqi Wu, Chuansheng Niu, Diane H Boschelli, Agnes Brennan

Bioorg Med Chem Lett· September 2009

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Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases.
Alexander Margulis, Karl H Nocka, Agnes M Brennan, Bijia Deng, Margaret Fleming

J Immunol· August 2009

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Optimization of 5-phenyl-3-pyridinecarbonitriles as PKCtheta inhibitors.
Diane H Boschelli, Daniel Wang, Amar S Prashad, Joan Subrath, Biqi Wu, Agnes Brennan

Bioorg Med Chem Lett· July 2009

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Synthesis and PKCtheta inhibitory activity of a series of 4-indolylamino-5-phenyl-3-pyridinecarbonitriles.
Russell G Dushin, Thomas Nittoli, Charles Ingalls, Diane H Boschelli, Derek C Cole, Agnes Brennan

Bioorg Med Chem Lett· May 2009

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Identification, characterization and initial hit-to-lead optimization of a series of 4-arylamino-3-pyridinecarbonitrile as protein kinase C theta (PKCtheta) inhibitors.
Derek C Cole, Magda Asselin, Agnes Brennan, Robert Czerwinski, John W Ellingboe

J Med Chem· October 2008

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